Compare Delsym vs. Advil Congestion Relief

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Relieves coughing.

Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.

3.3/ 5 average rating with 127 reviewsforDelsym
Relieves pain and congestion.

Advil Congestion Relief (Ibuprofen / Phenylephrine) is a good combination medicine to relieve pain and congestion, but it's more medicine than you need if you only have one symptom.

3.6/ 5 average rating with 1125 reviewsforAdvil Congestion Relief
Upsides
  • Good for treating dry cough.
  • Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
  • Available as a liquid and a tablet.
  • Some products relieve cough for up to 12 hours.
  • Advil Congestion Relief (Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
Downsides
  • Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
  • If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
  • If you don't really need both of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
Used for
Dosage forms
  • Pill
  • Liquid extended release
  • Pill
No pricing information available
No pricing information available
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Reviews
127 reviews so far
63%
saidit'sworth it
32%
saiditworked well
12%
saidit'sa big hassle

Have you used Delsym (Dextromethorphan)?

Leave a review
1125 reviews so far
73%
saidit'sworth it
32%
saiditworked well
7%
saidit'sa big hassle

Have you used Advil Congestion Relief (Ibuprofen / Phenylephrine)?

Leave a review
Side effects
The Delsym (Dextromethorphan) FDA package insert doesn’t have numbers about how common side effects are.
The Advil Congestion Relief (Ibuprofen / Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Serotonin syndrome
    • Using other medications that affect serotonin
See more detailed risks and warnings
  • Stomach bleeding
    • History of stomach bleeding or ulcers
    • Age 60 years or older
    • Taking aspirin, NSAIDs, or blood thinners
    • Drinking more than 3 alcoholic beverages a day
  • Harm to fetus
    • Women of childbearing age
  • High blood pressure
    • History of high blood pressure
  • Lower kidney function
    • Kidney disease
    • Heart failure
    • Liver disease
    • Taking high blood pressure medications
    • Age 65 years or older
  • Heart attack or stroke
    • History of heart problems
    • Age 65 years or older
    • Taking with aspirin
See more detailed risks and warnings