Compare Delsym vs. Advil Congestion Relief

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Delsym
(Dextromethorphan)

Advil Congestion Relief
(Ibuprofen / Phenylephrine)

Relieves coughing. Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.Relieves pain and congestion. Advil Congestion Relief (Ibuprofen / Phenylephrine) is a good combination medicine to relieve pain and congestion, but it's more medicine than you need if you only have one symptom.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.487394957983193Delsym
Reviews for Delsym (Dextromethorphan)
64%
of people say Delsym (Dextromethorphan) is worth it
31%
say it works well
12%
say it's a big hassle
Reviews for Advil Congestion Relief (Ibuprofen / Phenylephrine)
73%
+9% vs. Delsym (Dextromethorphan)
32%
+1% vs. Delsym (Dextromethorphan)
7%
+5% vs. Delsym (Dextromethorphan)
Side effects
DelsymAdvil Congestion Relief

We haven’t found good data for Delsym side effects.

FDA side effect reports for Delsym »

We haven’t found good data for Advil Congestion Relief side effects.

FDA side effect reports for Advil Congestion Relief »
How it works
DelsymAdvil Congestion Relief
Delsym (Dextromethorphan) is a cough suppressant.Advil Congestion Relief (Ibuprofen / Phenylephrine) is a combination medicine that treats cold and allergy symptoms. Ibuprofen is an NSAID that relieves swelling, pain, and fever. Phenylephrine is a decongestant that clears your sinuses.
Type of medication
DelsymAdvil Congestion Relief
Cough suppressantOver-the-counter
Pain reliever
NSAID
DecongestantOver-the-counter
Available as
DelsymAdvil Congestion Relief
  • Pill
  • Liquid extended release
  • Pill
Used for (click to learn more)
DelsymAdvil Congestion Relief
Risk factors for serious side effects
DelsymAdvil Congestion Relief
  • Using other medications that affect serotonin
Detailed Delsym (Dextromethorphan) risks & warnings »
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Women of childbearing age
  • History of high blood pressure
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking high blood pressure medications
  • Age 65 years or older
  • History of heart problems
  • Age 65 years or older
  • Taking with aspirin
Detailed Advil Congestion Relief (Ibuprofen / Phenylephrine) risks & warnings »
Pregnancy category
DelsymAdvil Congestion Relief
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
NFDA pregnancy category (Unknown)

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.
  • Advil Congestion Relief (Ibuprofen / Phenylephrine) contains ibuprofen, an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil Congestion Relief (Ibuprofen / Phenylephrine) for any amount of time.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
DelsymAdvil Congestion Relief
  • Good for treating dry cough.
  • Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
  • Available as a liquid and a tablet.
  • Some products relieve cough for up to 12 hours.
  • Advil Congestion Relief (Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
Downsides and risks
DelsymAdvil Congestion Relief
  • Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
  • If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
  • If you don't really need both of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
Tips from our pharmacists for people taking the medication
DelsymAdvil Congestion Relief
  • Cough suppressant starts working in 15 to 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • If your cough lasts more than 7 days, call your doctor.
  • Starts working in 30 minutes.
  • Don't take it if you have an allergy to aspirin since ibuprofen can cause a similar reaction.
  • Phenylephrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
  • Follow age-specific dosing instructions on how much to take. Don't take more than what's recommended on the package.
  • Let your doctor know if your symptoms don't improve in a few days.
Learn more
More about DelsymSide effectsReviews & ratingsAlternativesFDA package insert
More about Advil Congestion ReliefSide effectsReviews & ratingsAlternativesFDA package insert