Compare Delsym vs. Mucinex DM

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Delsym
(dextromethorphan)

Mucinex Dm
(dextromethorphan / guaifenesin)

Relieves coughing. Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.Breaks up mucus and relieves cough. Mucinex Dm (Dextromethorphan / Guaifenesin) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. It comes as an extended-release tablet and a short-acting liquid.
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Best available price for 120 (30mg/5ml) bottle of oral suspensions of dextromethorphan
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Reviews & ratings
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4.5Delsym
Reviews for Delsym (dextromethorphan)
63%
of people (All ages) say Delsym (dextromethorphan) is worth it
32%
say it works well
12%
say it's a big hassle
127 reviews
Have you used Delsym (dextromethorphan)?
Worth itNot sureNot worth it
Reviews for Mucinex Dm (dextromethorphan / guaifenesin)
73%
+10% better vs. Delsym (dextromethorphan)
73%
+41% better vs. Delsym (dextromethorphan)
13%
-1% worse vs. Delsym (dextromethorphan)
Have you used Mucinex Dm (dextromethorphan / guaifenesin)?
Worth itNot sureNot worth it
Side effects
DelsymMucinex DM

We haven’t found good data for Delsym side effects.

FDA side effect reports for Delsym »

We haven’t found good data for Mucinex DM side effects.

FDA side effect reports for Mucinex DM »
How it works
DelsymMucinex DM
Delsym (Dextromethorphan) is a cough suppressant.Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.
Type of medication
DelsymMucinex DM
Over-the-counter
Over-the-counter
Available as
DelsymMucinex DM
  • Pill
  • Liquid extended release
  • Pill
  • Extended release
  • Liquid
Used for
DelsymMucinex DM
Risk factors for serious side effects
DelsymMucinex DM
  • Using other medications that affect serotonin
Detailed Delsym (dextromethorphan) risks & warnings »
  • Using other medications that affect serotonin
Detailed Mucinex Dm (dextromethorphan / guaifenesin) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Upsides and benefits
DelsymMucinex DM
  • Good for treating dry cough.
  • Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
  • Available as a liquid and a tablet.
  • Some products relieve cough for up to 12 hours.
  • Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
  • The extended release version of Mucinex DM lasts up to 12 hours.
Downsides and risks
DelsymMucinex DM
  • Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
  • If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
  • Mucinex Dm (Dextromethorphan / Guaifenesin) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Mucinex Dm (Dextromethorphan / Guaifenesin)) stops you from coughing.
  • Can cause sleepiness, dizziness, and an upset stomach.
Tips from our pharmacists for people taking the medication
DelsymMucinex DM
  • Cough suppressant starts working in 15 to 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • If your cough lasts more than 7 days, call your doctor.
  • Cough suppressant starts working in 15 to 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • Drink plenty of fluids while taking Mucinex Dm (Dextromethorphan / Guaifenesin) because liquid helps break down mucus.
  • If your cough lasts more than 7 days, call your doctor.
Learn more
More about DelsymSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Delsym (dextromethorphan)?
Worth itNot sureNot worth it
More about Mucinex DMSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Mucinex Dm (dextromethorphan / guaifenesin)?
Worth itNot sureNot worth it