Compare Delsym vs. Sudafed PE Pressure Pain And Cough

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Delsym
(Dextromethorphan)

Sudafed Pe Pressure Pain And Cough
(Acetaminophen / Dextromethorphan / Phenylephrine)

Relieves coughing. Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.Relieves coughing and cold symptoms. Sudafed Pe Pressure Pain And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) is good for multiple cold symptoms, but it's more medicine than you need if you only have one symptom.
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Reviews & ratings
Filter group. All currently selected
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4.5Delsym
Reviews for Delsym (Dextromethorphan)
63%
of people (All ages) say Delsym (Dextromethorphan) is worth it
32%
say it works well
12%
say it's a big hassle
127 reviews
Have you used Delsym (Dextromethorphan)?
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Have you used Sudafed Pe Pressure Pain And Cough (Acetaminophen / Dextromethorphan / Phenylephrine)?
Worth itNot sureNot worth it
Side effects
DelsymSudafed PE Pressure Pain And Cough

We haven’t found good data for Delsym side effects.

FDA side effect reports for Delsym »

We haven’t found good data for Sudafed PE Pressure Pain And Cough side effects.

FDA side effect reports for Sudafed PE Pressure Pain And Cough »
How it works
DelsymSudafed PE Pressure Pain And Cough
Delsym (Dextromethorphan) is a cough suppressant.Sudafed Pe Pressure Pain And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) is a combination medicine that treats cold symptoms. Acetaminophen relieves pain and reduces fever. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses.
Type of medication
DelsymSudafed PE Pressure Pain And Cough
Over-the-counter
Over-the-counter
Available as
DelsymSudafed PE Pressure Pain And Cough
  • Pill
  • Liquid extended release
  • Pill
Used for
DelsymSudafed PE Pressure Pain And Cough
Risk factors for serious side effects
DelsymSudafed PE Pressure Pain And Cough
  • Using other medications that affect serotonin
Detailed Delsym (Dextromethorphan) risks & warnings »
  • Taking with alcohol
  • Taking with other Tylenol-containing medicines
  • History of liver disease
  • History of high blood pressure
  • Taking MAO inhibitors
  • History of chronic obstructive pulmonary disease (COPD)
  • History of smoking
  • Using other medications that affect serotonin
  • Women of childbearing age
Detailed Sudafed Pe Pressure Pain And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Kidneys and liver
DelsymSudafed PE Pressure Pain And Cough
No kidneys and liver related info.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
Pain
DelsymSudafed PE Pressure Pain And Cough
No pain related info.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
Upsides and benefits
DelsymSudafed PE Pressure Pain And Cough
  • Good for treating dry cough.
  • Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
  • Available as a liquid and a tablet.
  • Some products relieve cough for up to 12 hours.
  • Sudafed Pe Pressure Pain And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
Downsides and risks
DelsymSudafed PE Pressure Pain And Cough
  • Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
  • If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
Tips from our pharmacists for people taking the medication
DelsymSudafed PE Pressure Pain And Cough
  • Cough suppressant starts working in 15 to 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • If your cough lasts more than 7 days, call your doctor.
  • Starts working in about 30 minutes.
  • Phenylephrine, the decongestant, can make you restless, so don't take it too close to bedtime.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Let your doctor know if your symptoms don't improve in a few days, or if you have a really bad sore throat with a fever, headache, nausea, or vomiting.
Learn more
More about DelsymSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Delsym (Dextromethorphan)?
Worth itNot sureNot worth it
More about Sudafed PE Pressure Pain And CoughSide effectsAlternativesFDA package insert
Have you used Sudafed Pe Pressure Pain And Cough (Acetaminophen / Dextromethorphan / Phenylephrine)?
Worth itNot sureNot worth it