Compare Depakote vs. Latuda

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Depacon (Valproate, Valproic Acid, Or Divalproex)

Prescription only

Latuda (Lurasidone)

Prescription only
Prevents seizures and stabilizes mood.

Depacon (Valproate, Valproic Acid, Or Divalproex) is good long-term prevention for epilepsy, bipolar disorder, and migraines, but can cause weight gain.

4.4/ 7 average rating with 97 reviewsforDepakote
Helps control your thoughts and mood.

Latuda (Lurasidone) is good for treating schizophrenia and depression related to bipolar disorder. It's less likely to cause weight gain, cholesterol, blood sugar, and heart rhythm problems.

5.2/ 7 average rating with 61 reviewsforLatuda
Upsides
  • Lowers the frequency of seizures, especially for people with absence, tonic-clonic, and complex partial seizures.
  • One of the first-line options to stabilize mood for people with bipolar disorder.
  • Helpful in preventing frequent migraine headaches.
  • Has been shown in clinical studies to help people felt better and experience improvements with their thoughts and mood.
  • It’s a newer type of medication and works differently than traditional antidepressants.
  • Can be taken alone or with other medications that manage your mood.
  • Compared to other antipsychotics, it has a lower risk of causing weight gain and changes to cholesterol, blood sugar, and heart rhythm.
Downsides
  • Can cause upset stomach, hair loss, weight gain, sleepiness, and tremor.
  • Can cause liver damage, so it's probably not safe if you already have liver problems.
  • Not safe to use if you're pregnant.
  • Requires routine blood tests to see how the medicine is affecting your body.
  • Certain antifungal and heart medicines can increase the amount of Latuda (Lurasidone) in your body and put you at risk for more side effects. Ask your doctor or pharmacist about any drug interactions between medicines you’re taking.
  • Can cause you to be more sensitive to heat and make it harder for your body to cool off.
  • Need to avoid drinking alcohol while taking Latuda (Lurasidone).
  • Elderly people who have dementia shouldn't take Latuda (Lurasidone).
Used for
Dosage forms
  • Pill
  • Extended release
  • Extended release capsule
  • Sprinkle
  • Liquid
  • Pill
Price
Lowest price near you
$293.48
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Lowest price near you
$1055
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Reviews
97 
46%
think this treatment is worth it
40%
think this treatment works well
27%
think this treatment is a hassle

Have you used Depacon (Valproate, Valproic Acid, Or Divalproex)?

Leave a review
61 
61%
think this treatment is worth it
61%
think this treatment works well
25%
think this treatment is a hassle

Have you used Latuda (Lurasidone)?

Leave a review
Side effects
10possible side effects
  • Nausea
    48%
  • Headache
    31%
  • Asthenia
    27%
  • Vomiting
    27%
  • Somnolence
    27%
  • Tremor
    25%
  • Dizziness
    25%
  • Abdominal Pain
    23%
  • Diplopia
    16%
  • Diarrhea
    13%
See more detailed side effects
10possible side effects
  • Somnolence
    22%
  • Akathisia
    15%
  • Nausea
    12%
  • Parkinsonism
    11%
  • Any side effect
    9%
  • Vomiting
    8%
  • Dyspepsia
    8%
  • Insomnia
    8%
  • Agitation
    6%
  • Anxiety
    6%
See more detailed side effects
Risks and warnings
  • Liver damage

    Children under age 2

    ...and 1 more risk factors

  • Suicidal thoughts or behavior

    History of depression

  • Mental changes due to high ammonia

    History of metabolic disorders

    ...and 1 more risk factors

  • Low body temperature

    People also taking Topamax

  • Withdrawal seizures

    Stopping Depacon (Valproate, Valproic Acid, Or Divalproex) suddenly

See more detailed risks and warnings
  • Increased risk of death

    Elderly patients with dementia

  • Suicidal thoughts or behavior

    Age 18 years or younger

  • Abnormal and involuntary muscle movements

    Duration of treatment

  • Sedation and driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Higher blood sugar and cholesterol

    History of diabetes

    ...and 1 more risk factors

See more detailed risks and warnings