Compare Depo-Testosterone vs. Aveed

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Depo-Testosterone
(Testosterone Cypionate Injection)

Aveed
(Testosterone Undecanoate Injection)

Treats low testosterone. This testosterone injection only has to be given once or twice a month and you can do it at home, but someone has to help you inject.Treats low testosterone. This testosterone injection is a first-choice treatment, but you have to get it in your doctor's office each time.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.010204081632653Depo-Testosterone
Reviews for Depo-Testosterone (Testosterone Cypionate Injection)
48%
of people say Depo-Testosterone (Testosterone Cypionate Injection) is worth it
31%
say it works well
17%
say it's a big hassle
Reviews for Aveed (Testosterone Undecanoate Injection)
42%
6% vs. Depo-Testosterone (Testosterone Cypionate Injection)
22%
9% vs. Depo-Testosterone (Testosterone Cypionate Injection)
18%
1% vs. Depo-Testosterone (Testosterone Cypionate Injection)
Side effects
Depo-TestosteroneAveed

The Depo-Testosterone FDA package insert doesn’t have numbers about how common side effects are.

More about Depo-Testosterone side effects »

The Aveed FDA package insert doesn’t have numbers about how common side effects are.

More about Aveed side effects »
How it works
Depo-TestosteroneAveed
The testosterone injection works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.The testosterone injection works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.
Type of medication
Depo-TestosteroneAveed
Hormone replacement
Testosterone
Prescription only
Hormone replacement
Testosterone
Prescription only
Available as
Depo-TestosteroneAveed
  • Injection
  • Injection
Used for (click to learn more)
Depo-TestosteroneAveed
  • Low testosterone
  • Low testosterone
Risk factors for serious side effects
Depo-TestosteroneAveed
  • Male
  • Male
  • Enlarged prostate (benign prostatic hypertrophy)
  • Taking high doses of Depo-Testosterone (Testosterone Cypionate Injection)
  • Heart, liver or kidney disease
  • Inability to move
  • Cancer
      • Diabetes
      • On blood thinners
        Detailed Depo-Testosterone (Testosterone Cypionate Injection) risks & warnings »
        • Male
        • Male
        • Enlarged prostate (benign prostatic hypertrophy)
        • Taking high doses of Aveed (Testosterone Undecanoate Injection)
        • Heart, liver or kidney disease
        • Inability to move
        • Cancer
            • Diabetes
            • On blood thinners
              • Taking medications to lower cholesterol
                Detailed Aveed (Testosterone Undecanoate Injection) risks & warnings »
                Pregnancy category
                Depo-TestosteroneAveed
                Alcohol
                No specific alcohol-related info.No specific alcohol-related info.
                Food
                No specific food-related info.No specific food-related info.
                Kidneys and liver
                • There have been reports of people on Depo-Testosterone (Testosterone Cypionate Injection) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This can happen if you are unable to move around or have cancer. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
                • There have been reports of people on Aveed (Testosterone Undecanoate Injection) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This can happen if you are unable to move around or if you have cancer. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
                Sex
                • Can cause increased acne and changes in sex drive.
                • If you're a man taking Depo-Testosterone (Testosterone Cypionate Injection), you can see changes in your sex drive, including overstimulation and prolonged frequent erections. Talk to your doctor if this happens, since they might have to change the dose.
                • Can cause increased acne and changes in sex drive.
                • If you're a man taking Aveed (Testosterone Undecanoate Injection), you can see changes in your sex drive, including overstimulation and prolonged frequent erections. Talk to your doctor if this happens, since they might have to change the dose.
                Sleep
                No specific sleep-related info.No specific sleep-related info.
                Weight
                • If you're taking Depo-Testosterone (Testosterone Cypionate Injection), and you notice swelling in your legs, or a sudden increase in your weight, talk to your doctor. This can be a serious side effect involving your heart.
                • If you're taking Aveed (Testosterone Undecanoate Injection), and you notice swelling in your legs, or a sudden increase in your weight, talk to your doctor. This can be a serious side effect involving your heart.
                Upsides and benefits
                Depo-TestosteroneAveed
                • A first-choice treatment for low testosterone in men and delayed puberty in boys.
                • Available in generic.
                • Only has to be given once every 2 to 4 weeks.
                • The shot can be done at home.
                • A first-choice treatment for low testosterone in men.
                • The first two shots are spaced out by a month, then each shot after that is given every 10 weeks.
                • Your doctor will give you the shot.
                Downsides and risks
                Depo-TestosteroneAveed
                • Only available as a shot.
                • Has to be given by someone else since it has to be injected into your buttocks.
                • Your doctor has to give you this shot. You can't do it at home.
                • Your doctor has to watch you for 30 minutes after your shot to make sure you don't have problems breathing or get a severe allergic reaction.
                • Your doctor has to file paperwork each time you get the shot because of the risks involved.
                • Not available as a generic, so it can be expensive.
                Tips from our pharmacists for people taking the medication
                Depo-TestosteroneAveed
                • Your doctor will show you how to inject this correctly.
                • Keep this medication locked up and away from children since it's a controlled substance.
                • Can cause nausea, vomiting and headache.
                • Can cause increased acne and changes in sex drive.
                • This medication is only available through a special screening program because of the side effects.
                • Your doctor will watch you for 30 minutes after each injection to make sure you don't have problems breathing or get an allergic reaction.
                • Can cause nausea, vomiting and headache.
                • Can cause increased acne and changes in sex drive.
                Learn more
                More about Depo-TestosteroneSide effectsReviews & ratingsAlternativesFDA package insert
                More about AveedSide effectsReviews & ratingsAlternativesFDA package insert