Compare Dexamethasone vs. Fludrocortisone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Decadron
(dexamethasone)

fludrocortisone

Lowers inflammation and suppresses your immune system. Decadron (Dexamethasone) is identical to an essential hormone that humans produce and has been proven to work safely.Coming soon.
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Prices and coupon for 60 (4mg) tablets of dexamethasone
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Prices and coupon for 30 (0.1mg) tablets of fludrocortisone
Reviews & ratings
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Have you used Decadron (dexamethasone)?
Worth itNot sureNot worth it

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Have you used Fludrocortisone?
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Side effects
DexamethasoneFludrocortisone

The Dexamethasone FDA package insert doesn’t have numbers about how common side effects are.

More about Dexamethasone side effects »

We haven’t found good data for Fludrocortisone side effects.

FDA side effect reports for Fludrocortisone »
How it works
DexamethasoneFludrocortisone
Decadron (Dexamethasone) is a short-acting corticosteroid. It lowers inflammation by preventing your capillaries (small blood vessels) from leaking out excess fluid and chemicals that cause swelling.Coming soon.
Type of medication
DexamethasoneFludrocortisone
Prescription only
Available as
DexamethasoneFludrocortisone
  • Pill
  • Liquid
  • Pill
Used for
DexamethasoneFludrocortisone
  • Addisons Disease Adrenal Insufficiency Adrenogenital Disorder
Risk factors for serious side effects
DexamethasoneFludrocortisone
  • Lowering dose or stopping too quickly especially after long-term treatment
  • Stress such as trauma, surgery or infection
  • Long-term treatment
  • Not vaccinated against viral diseases
  • Contact with people who have viral illness
  • History of bacterial or viral conditions
  • Duration of treatment
  • History of psychiatric conditions
  • Dose of Decadron (Dexamethasone)
  • Duration of treatment
  • Women of childbearing age
Detailed Decadron (dexamethasone) risks & warnings »
Coming soon.
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
DexamethasoneFludrocortisone
  • Adrenal suppression leading to adrenal crisis can occur if you lower your dose or stop taking Decadron (Dexamethasone) too quickly. Symptoms include joint or muscle pain, extreme low energy and depression. Changes in your Decadron (Dexamethasone) dose need to be done slowly over time. Talk to your doctor before you make any changes or stop the medication.
No kidneys and liver related info.
Weight
DexamethasoneFludrocortisone
  • Some people gain weight while taking Decadron (Dexamethasone) or can experience other side effects like mood changes.
No weight related info.
Upsides and benefits
DexamethasoneFludrocortisone
  • Treats a large variety of inflammatory disorders including asthma, dermatitis, drug reactions, rashes, and endocrine disorders.
  • Can help prevent nausea, especially when it's caused by chemotherapy.
  • You can get it orally or as an injection.
Coming soon
Downsides and risks
DexamethasoneFludrocortisone
  • Can't be used on its own to treat low cortisol levels.
  • Since it suppresses your immune system, you're more likely to get infections.
  • You can't take Decadron (Dexamethasone) if you have a systemic fungal infection.
  • Shouldn't be used if you have a stomach ulcer.
  • Can decrease bone formation and lead to an increased risk of osteoporosis.
Coming soon
Tips from our pharmacists for people taking the medication
DexamethasoneFludrocortisone
  • The lowest possible dose of corticosteroids should be used to control your symptoms.
  • When reducing or stopping the dose, do it very slowly and follow your doctor's instructions exactly to prevent major health emergencies.
  • If you used Decadron (Dexamethasone) for a long time, you could get withdrawal symptoms like muscle pain, joint pain, and malaise.
  • Some people gain weight while taking Decadron (Dexamethasone) or can experience other side effects like mood changes.
  • Don't get live or live/attenuated vaccines while on this. Killed or inactivated vaccines are fine.
Coming soon
Learn more
More about DexamethasoneSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Decadron (dexamethasone)?
Worth itNot sureNot worth it
More about FludrocortisoneSide effectsFDA package insert
Have you used Fludrocortisone?
Worth itNot sureNot worth it