Compare Dexilant vs. Prevacid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dexilant
(Dexlansoprazole)

Prevacid
(lansoprazole)

Treats heartburn and ulcers. Dexilant (Dexlansoprazole) is an effective medicine to treat heartburn and ulcers, but can be expensive.Treats heartburn and stomach ulcers. Prevacid (lansoprazole) is an effective and inexpensive acid reducer commonly used to provide heartburn relief and help heal ulcers.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
6.6Dexilant
Reviews for Dexilant
93%
of people (All ages) say Dexilant is worth it
92%
say it works well
14%
say it's a big hassle
Have you used Dexilant (Dexlansoprazole)?
Worth itNot sureNot worth it
Reviews for Prevacid
71%
+22% better vs. Dexilant
71%
+21% better vs. Dexilant
19%
+5% better vs. Dexilant
Have you used Prevacid (lansoprazole)?
Worth itNot sureNot worth it
Side effects
DexilantPrevacid
  • Upper Respiratory Tract Infection 1%
  • Vomiting 1%
  • Flatulence 1%
  • Diarrhea 2%
More Dexilant side effects »
  • Abdominal pain 1%
  • Diarrhea 2%
More Prevacid side effects »
How it works
DexilantPrevacid
Dexilant (Dexlansoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.Prevacid (lansoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach by blocking the final step of stomach acid production.
Type of medication
DexilantPrevacid
Prescription onlyNo lower cost generic availablePrescription or OTCLower-cost generic available
Available as
DexilantPrevacid
  • Extended release
  • Extended release
  • Dissolving tablet extended release
  • Liquid
Used for
DexilantPrevacid
Risk factors for serious side effects
DexilantPrevacid
  • Helicobacter pylori infection
  • Autoimmune disease
  • Being hospitalized
  • Antibiotic use
  • Osteoporosis
Detailed Dexilant (Dexlansoprazole) risks & warnings »
  • High dose Prevacid (lansoprazole)
  • Long-term treatment with Prevacid (lansoprazole)
  • Low bone mineral density
  • Older age
Detailed Prevacid (lansoprazole) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Price
DexilantPrevacid
No price related info.
  • Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
Interactions
DexilantPrevacid
  • Many drugs can interact with Dexilant (Dexlansoprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • Some prescription drugs can interact with Prevacid (lansoprazole), so talk to your doctor or pharmacist about the medicines you are taking.
Food
DexilantPrevacid
  • Take Dexilant (Dexlansoprazole) with or without food. It can work better for some people if it's taken 30 minutes before a meal.
No food related info.
Kidneys and liver
DexilantPrevacid
No kidneys and liver related info.
  • Prevacid (lansoprazole) can cause acute kidney damage that can occur at any time during treatment. Stop taking Prevacid (lansoprazole) and speak to your doctor immediately if you notice blood in the urine, changes in urine output, swelling of the body, weight gain, fever, or confusion.
Pain
DexilantPrevacid
  • Call your doctor if you have watery stools, stomach pain, or a fever because it could be a sign of a serious infection.
No pain related info.
Upsides and benefits
DexilantPrevacid
  • Relieves heartburn symptoms and heals ulcers better than other stomach medicines, such as Pepcid, Tagamet, and Zantac.
  • Lasts longer than other similar stomach medicines. Most people take it once a day.
  • Your body won't develop a tolerance to Dexilant (Dexlansoprazole), so it'll work the same way as long as you need to keep taking it.
  • Once heartburn symptoms are treated, a low dose of Dexilant (Dexlansoprazole) can be taken daily.
  • Most people can take Prevacid (lansoprazole) without any noticeable day-to-day side effects.
  • Comes in a dissolving tablet to be placed on the tongue if you cannot or do not like to swallow pills.
  • Prevacid (lansoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
Downsides and risks
DexilantPrevacid
  • Taking Dexilant (Dexlansoprazole) in high doses or for longer than 1 year can increase the risk for bone fractures, especially if you already have osteoporosis (weak bones).
  • Many drugs can interact with Dexilant (Dexlansoprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • There's no generic version available, so it can be expensive.
  • Doesn't start working right away like some other acid reducers (Tums, Rolaids, or Maalox).
  • May not be the best choice for patients 65 years of age and older due to risk of bone fractures and C. diff infection (bacterial).
  • Is used if you have frequent heartburns that occur more than 2 days per week. Speak to your doctor or pharmacist if you only have occasional heartburn.
Tips from our pharmacists for people taking the medication
DexilantPrevacid
  • Can take a few days to start working.
  • Take Dexilant (Dexlansoprazole) with or without food. It can work better for some people if it's taken 30 minutes before a meal.
  • Call your doctor if you have watery stools, stomach pain, or a fever because it could be a sign of a serious infection.
  • Dexilant (Dexlansoprazole) can lower the amount of magnesium in your body. Initial and follow-up blood tests may be needed before starting Dexilant (Dexlansoprazole).
  • Take Prevacid (lansoprazole) with a full glass of water before eating.
  • Starts working in 1 to 3 hours. It can take 1 to 4 days to take full effect.
  • Some prescription drugs can interact with Prevacid (lansoprazole), so talk to your doctor or pharmacist about the medicines you are taking.
  • Do not take for more than 14 days, unless directed by your doctor. Speak to your doctor if your symptoms don't go away after 2 weeks.
  • Prevacid (lansoprazole) capsules can be opened and sprinkled on 1 tablespoon of applesauce, cottage cheese, or yogurt. Swallow immediately after. The dissolving tablets shouldn't be swallowed, broken, or chewed.
Learn more
More about DexilantSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Dexilant (Dexlansoprazole)?
Worth itNot sureNot worth it
More about PrevacidSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Prevacid (lansoprazole)?
Worth itNot sureNot worth it