Compare Dexilant vs. Prevacid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dexilant
(dexlansoprazole)

Prevacid
(lansoprazole)

Treats heartburn and ulcers. Dexilant (Dexlansoprazole) is an effective medicine to treat heartburn and ulcers, but can be expensive.Treats heartburn and stomach ulcers. Prevacid (Lansoprazole) gives you long-lasting heartburn relief and helps heal ulcers.
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Coupons for Dexilant
Best available price for 30 (60mg) capsules of dexlansoprazole
Coupons for Prevacid
Best available price for 30 (30mg) capsules of lansoprazole
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
6.6Dexilant
Reviews for Dexilant (dexlansoprazole)
93%
of people (All ages) say Dexilant (dexlansoprazole) is worth it
92%
say it works well
14%
say it's a big hassle
Have you used Dexilant (dexlansoprazole)?
Worth itNot sureNot worth it
Reviews for Prevacid (lansoprazole)
71%
-22% worse vs. Dexilant (dexlansoprazole)
71%
-21% worse vs. Dexilant (dexlansoprazole)
19%
-5% worse vs. Dexilant (dexlansoprazole)
Have you used Prevacid (lansoprazole)?
Worth itNot sureNot worth it
Side effects
DexilantPrevacid
  • Diarrhea 2%
  • Ear, nose, or throat infection 1%
  • Vomiting 1%
  • Passing gas 1%
More Dexilant side effects »
  • Diarrhea 2%
  • Abdominal pain 1%
More Prevacid side effects »
How it works
DexilantPrevacid
Dexilant (Dexlansoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.Prevacid (Lansoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers.
Type of medication
DexilantPrevacid
Prescription only
Prescription or OTC
Available as
DexilantPrevacid
  • Extended release
  • Extended release
  • Dissolving tablet extended release
Used for
DexilantPrevacid
Risk factors for serious side effects
DexilantPrevacid
  • Helicobacter pylori infection
  • Autoimmune disease
  • Being hospitalized
  • Antibiotic use
  • Osteoporosis
Detailed Dexilant (dexlansoprazole) risks & warnings »
  • Helicobacter pylori infection
  • Autoimmune disease
  • Being hospitalized
  • Antibiotic use
  • Osteoporosis
Detailed Prevacid (lansoprazole) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Interactions
DexilantPrevacid
  • Many drugs can interact with Dexilant (Dexlansoprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • Can interact with other drugs, so be sure your doctor knows all the medicine you're taking before starting Prevacid (Lansoprazole).
  • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Prevacid (Lansoprazole).
Food
DexilantPrevacid
  • Take Dexilant (Dexlansoprazole) with or without food. It can work better for some people if it's taken 30 minutes before a meal.
  • Take Prevacid (Lansoprazole) about 1 hour before a meal.
Pain
DexilantPrevacid
  • Call your doctor if you have watery stools, stomach pain, or a fever because it could be a sign of a serious infection.
No pain related info.
Upsides and benefits
DexilantPrevacid
  • Relieves heartburn symptoms and heals ulcers better than other stomach medicines, such as Pepcid, Tagamet, and Zantac.
  • Lasts longer than other similar stomach medicines. Most people take it once a day.
  • Your body won't develop a tolerance to Dexilant (Dexlansoprazole), so it'll work the same way as long as you need to keep taking it.
  • Once heartburn symptoms are treated, a low dose of Dexilant (Dexlansoprazole) can be taken daily.
  • Most people can take Prevacid (Lansoprazole) without any noticeable day-to-day side effects.
  • Prevacid (Lansoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Available as both a generic and over-the-counter option, so it's pretty affordable.
  • Sometimes if one PPI doesn't work, another medication in the same class will work for you.
Downsides and risks
DexilantPrevacid
  • Taking Dexilant (Dexlansoprazole) in high doses or for longer than 1 year can increase the risk for bone fractures, especially if you already have osteoporosis (weak bones).
  • Many drugs can interact with Dexilant (Dexlansoprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • There's no generic version available, so it can be expensive.
  • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
  • Depending on the condition you are treating, it can take one to two weeks to get the full effect.
  • If you are taking Prevacid (Lansoprazole) for a long time you should take a calcium supplement to prevent fragile bones.
  • Can interact with other drugs, so be sure your doctor knows all the medicine you're taking before starting Prevacid (Lansoprazole).
Tips from our pharmacists for people taking the medication
DexilantPrevacid
  • Can take a few days to start working.
  • Take Dexilant (Dexlansoprazole) with or without food. It can work better for some people if it's taken 30 minutes before a meal.
  • Call your doctor if you have watery stools, stomach pain, or a fever because it could be a sign of a serious infection.
  • Dexilant (Dexlansoprazole) can lower the amount of magnesium in your body. Initial and follow-up blood tests may be needed before starting Dexilant (Dexlansoprazole).
  • Take Prevacid (Lansoprazole) about 1 hour before a meal.
  • Don't chew or crush capsules, but swallow them whole.
  • If you have trouble swallowing, there's a tablet available that dissolves in your mouth.
  • Give Prevacid (Lansoprazole) a chance to work. You'll see some benefits right away, but the full effects can take a week or so to kick in.
  • Avoid drug interactions by telling your doctor all of the other medications or herbal supplements you take before starting Prevacid (Lansoprazole).
Learn more
More about DexilantSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Dexilant (dexlansoprazole)?
Worth itNot sureNot worth it
More about PrevacidSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Prevacid (lansoprazole)?
Worth itNot sureNot worth it