Compare Dexilant vs. Tagamet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tagamet (cimetidine)

Prescription or OTC
Treats heartburn and ulcers.

Dexilant (Dexlansoprazole) is an effective medicine to treat heartburn and ulcers, but can be expensive.

4.7/ 5 average rating with 73 reviewsforDexilant
Treats heartburn.

Tagamet (cimetidine) works well for heartburn, but may have more side effects than other medicines like it.

3.4/ 5 average rating with 632 reviewsforTagamet
Upsides
  • Relieves heartburn symptoms and heals ulcers better than other stomach medicines, such as Pepcid, Tagamet, and Zantac.
  • Lasts longer than other similar stomach medicines. Most people take it once a day.
  • Your body won't develop a tolerance to Dexilant (Dexlansoprazole), so it'll work the same way as long as you need to keep taking it.
  • Once heartburn symptoms are treated, a low dose of Dexilant (Dexlansoprazole) can be taken daily.
  • Lasts longer than other medicines like it so you may not need to take it as frequently.
  • Affordable as an over-the-counter or generic medicine.
Downsides
  • Taking Dexilant (Dexlansoprazole) in high doses or for longer than 1 year can increase the risk for bone fractures, especially if you already have osteoporosis (weak bones).
  • Many drugs can interact with Dexilant (Dexlansoprazole), so talk to your doctor or pharmacist before starting any new medicines.
  • There's no generic version available, so it can be expensive.
  • Does not work as fast as antacids like Maalox, Tums, or Rolaids.
  • May not work as well if you have an inflammed esophagus. Your doctor will assess which medicine is best for you.
  • May not be the best option if you are elderly or have kidney or liver problems.
  • Can interfere with how other medicines work.
Used for
Dosage forms
  • Extended release
  • Pill
  • Liquid
Price
No pricing information available
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Reviews
73 reviews so far
93%
saidit'sworth it
92%
saiditworked well
14%
saidit'sa big hassle

Have you used Dexilant (Dexlansoprazole)?

Leave a review
632 reviews so far
63%
saidit'sworth it
36%
saiditworked well
12%
saidit'sa big hassle

Have you used Tagamet (cimetidine)?

Leave a review
Side effects
6possible side effects
  • Diarrhea
    5%
  • Abdominal Pain
    4%
  • Nausea
    3%
  • Upper Respiratory Tract Infection
    2%
  • Vomiting
    2%
  • Flatulence
    2%
See more detailed side effects
The Tagamet (cimetidine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Hiding possible cancer
  • Severe stomach inflammation (atrophic gastritis)
    • Helicobacter pylori infection
    • Autoimmune disease
  • Severe diarrhea
    • Being hospitalized
    • Antibiotic use
  • Broken bones
    • Osteoporosis
    • Age 50 or older
    • Using high medication doses
    • Long-term therapy (1 year or more)
    • Smoking
    • Use of other medications that weaken bones
  • Low vitamin or mineral levels
See more detailed risks and warnings
  • Confusion
    • Elderly
    • Kidney problems
    • Liver problems
    • Dementia
  • Drug interactions
  • Chronic lung problems
    • Asthma
    • COPD
    • Lung problems
  • Clostridium difficile associated diarrhea
    • Taking antibiotics
  • Englarged breasts in men (gynecomastia)
See more detailed risks and warnings