Compare Diclofenac vs. Coumadin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zorvolex (Diclofenac)

Prescription only

Coumadin (warfarin)

Prescription only
Treats arthritis pain and swelling.

Zorvolex (Diclofenac) is an okay medication used to treat pain and swelling caused by arthritis. However, because of the risk of heart attack, you should limit the amount you take.

Prevents blood clots.

Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.

5.2/ 7 average rating with 513 reviewsforCoumadin
Upsides
  • Clinical studies show that Zorvolex (Diclofenac) is better at relieving arthritis pain than acetaminophen (Tylenol).
  • Can be used as needed to treat pain and swelling.
  • Available as a generic.
  • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
  • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
  • Coumadin (warfarin) comes in numerous strengths.
  • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
Downsides
  • You should avoid alcohol while on Zorvolex (Diclofenac) since it can increase your risk of stomach issues.
  • If you're taking it on a regular basis, you'll need to get labs done to make sure your liver and kidneys aren't being affected.
  • Raises your risk of bleeding and bruising.
  • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
  • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
Used for
  • Osteoarthritis pain
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$334.28
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$4
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Reviews
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513 
61%
think this treatment is worth it
54%
think this treatment works well
21%
think this treatment is a hassle

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Side effects
9possible side effects
  • Upper respiratory tract infection
    8%
  • Headache
    8%
  • Nausea
    7%
  • Urinary tract infection
    7%
  • Diarrhea
    6%
  • Nasopharyngitis
    6%
  • Constipation
    5%
  • Sinusitis
    5%
  • Osteoarthritis
    5%
See more detailed side effects
The Coumadin (warfarin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Heart attack or stroke

    History of heart problems

    ...and 5 more risk factors

  • Stomach bleeding

    History of stomach bleeding or ulcers

    ...and 1 more risk factors

  • Bruising or bleeding

    Bleeding disorder

    ...and 1 more risk factors

  • Serious allergic reactions

    Asthma

    ...and 4 more risk factors

  • Lowers kidney function

    Kidney problems

    ...and 5 more risk factors

  • Increased blood pressure

    History of high blood pressure

    ...and 1 more risk factors

See more detailed risks and warnings
  • Life threatening bleeding

    Coumadin (warfarin) dose too high

    ...and 8 more risk factors

  • Harm to fetus

    Women of childbearing age

See more detailed risks and warnings