Compare Differen vs. Benzoyl Peroxide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

No information currently available
Topical treatment for acne and skin wounds.

Benzac (Benzoyl Peroxide) is a very popular topical acne treatment you can get over-the-counter or by prescription that may be better for people who don't want to take pill medication. Just be careful because it can bleach your hair, clothing and other fabrics.

3.4/ 5 average rating with 394 reviewsforBenzoyl Peroxide
Upsides
No information currently available
  • Benzoyl peroxide is used to reduce bacteria on the skin, which "calms" the skin down (lowers the inflammatory response) in acne.
  • Helps stop blemishes from forming when oil and skin cells become trapped in pores.
  • Although Benzoyl peroxide can irritate the skin, a true skin allergy is rare.
  • Can be used in combination with acne pill medicine if your doctor thinks you need it.
  • It's available in non-prescription strengths, easy to buy at any drugstore and pretty cheap compared to prescription pills to treat your acne.
Downsides
No information currently available
  • Higher strengths (concentrations) can cause skin irritation and may appear as redness, peeling, abnormal dryness or stinging, tightening, or burning sensations.
  • It's rare, that a serious allergic reaction would occur, but it's a good idea to test a small area of skin before using on any larger or sensitive areas.
  • Not the best choice if you're pregnant. Benzoyl peroxide is categorized as pregnancy Category C (weigh risks vs benefits) as compared to similar topical medicines that are in Category B (likely safe).
  • Can cause bleaching of hair and clothing.
  • May not work as well when used by itself over long period of time.
  • You'll need to stay out of the sun or apply a sunscreen if you have to be outdoors.
Used for
  • Acne vulgaris
Dosage forms
  • Cream, gel, or ointment
  • Cream, gel, or ointment
  • Lotion
  • Liquid
  • Topical solution
Price
No pricing information available
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Reviews
Not enough review data.Leave a review
394 reviews so far
60%
saidit'sworth it
29%
saiditworked well
9%
saidit'sa big hassle

Have you used Benzac (Benzoyl Peroxide)?

Leave a review
Side effects
The Differen (Adapalene) FDA package insert doesn’t have numbers about how common side effects are.
The Benzac (Benzoyl Peroxide) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
No information currently available
  • Bleaching effects
  • Skin irritation
    • Using other medicines or products that irritate the skin
    • Eczema
    • Extreme temperatures (hot or cold)
  • Allergic reaction
See more detailed risks and warnings