Compare Differen vs. Cleocin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Differen
(adapalene)

Cleocin T
(clindamycin phosphate)

Coming soon.Topical treatment for acne. Cleocin T (Clindamycin Phosphate) is good for treating many bacterial infections and is available as a generic. If you're taking the vaginal form, you have to avoid sex and tampons for the period your doctor tells you to. The topical form can cause skin sensitivity and irritation.
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Reviews & ratings
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Have you used Differen (adapalene)?
Worth itNot sureNot worth it
Reviews for Cleocin T (clindamycin phosphate)
57%
+24% better vs. Differen (adapalene)
43%
+10% better vs. Differen (adapalene)
19%
+14% better vs. Differen (adapalene)
115 reviews
Have you used Cleocin T (clindamycin phosphate)?
Worth itNot sureNot worth it
Side effects
DifferenCleocin

We haven’t found good data for Differen side effects.

FDA side effect reports for Differen »
  • Any side effect 21%
  • Vaginal moniliasis 8%
  • Vulvovaginitis 6%
  • Vulvovaginal disorder 3%
  • Moniliasis (body) 2%
  • Fungal infection 2%
More Cleocin side effects »
How it works
DifferenCleocin
Coming soon.Cleocin T (Clindamycin Phosphate) is an antibiotic and acne medicine. It kills bacteria by preventing them from reproducing and repairing themselves.
Type of medication
DifferenCleocin
Prescription only
Available as
DifferenCleocin
  • Cream, gel, or ointment
  • Topical
  • Cream, gel, or ointment
  • Foam
  • Vaginal cream
  • Vaginal suppository
  • Injection
Used for
DifferenCleocin
  • Acne Vulgaris
Risk factors for serious side effects
DifferenCleocin
Coming soon.
    • History of liver disease
      Detailed Cleocin T (clindamycin phosphate) risks & warnings »
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

      Food
      DifferenCleocin
      No food related info.
      • Can be taken with or without food.
      Kidneys and liver
      DifferenCleocin
      No kidneys and liver related info.
      • There have been reports of liver damage that can require hospitalization or can cause death. These have been rare. Talk to your doctor if you notice pain in your abdomen, loss of appetite, yellowing of your skin or eyes, or dark colored urine.
      Pain
      DifferenCleocin
      No pain related info.
      • The forms taken by mouth can cause diarrhea, vomiting, and abdominal pain.
      Upsides and benefits
      DifferenCleocin
      Coming soon
      • Available in generic.
      • Topical form treats acne.
      • Available in different oral forms: tablet, capsule, and suspension.
      • Available in forms to treat skin infections and vaginal infections.
      • Used to treat many types of bacterial infections.
      • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
      • Can be taken with or without food.
      Downsides and risks
      DifferenCleocin
      Coming soon
      • Have to take the oral forms with a full glass of liquid or with food since it can cause irritation in your stomach and esophagus.
      • If you're taking the vaginal form, you have to avoid sex and not use tampons for the period your doctor tells you to.
      • If you're allergic to aspirin, your doctor may have to prescribe an alternate.
      • If you have to take live vaccines, talk to your doctor when to take them since Clindamycin can make it less effective.
      • If you're taking the topical form, it can cause sensitivity and irritation.
      Tips from our pharmacists for people taking the medication
      DifferenCleocin
      Coming soon
      • The forms taken by mouth can cause diarrhea, vomiting, and abdominal pain.
      • Take this medication exactly how your doctor tells you to.
      • Store the suspension at room temperature.
      • If you're using the topical form, it can take a few weeks to see the full effect.
      • Keep the topical form out of your eyes, nose and mouth.
      • If you're using the topical form, Don't put makeup or bandages over it.
      • If you're using the vaginal form, don't have sex before the doctor tells you it's ok.
      Learn more
      More about DifferenSide effectsReviews & ratingsFDA package insert
      Have you used Differen (adapalene)?
      Worth itNot sureNot worth it
      More about CleocinSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Cleocin T (clindamycin phosphate)?
      Worth itNot sureNot worth it