Compare Differen vs. Minocycline

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Differen (Adapalene)

Solodyn (Minocycline)

Prescription only
No information currently available
Treats bacterial infections.

Solodyn (Minocycline) is an effective way to treat certain skin infections, acne, and rosacea, but you'll need to use barrier methods of birth control since it can make birth control pills less effective and cause birth defects.

5.5/ 7 average rating with 17 reviewsforMinocycline
Upsides
No information currently available
  • Clinical studies show it's effective against MRSA, a common skin infection, and it's commonly used to treat acne and rosacea.
  • Available as a generic, so it should be reasonably priced.
  • Solodyn (Minocycline) is less likely to cause sunburn than other tetracycline antibiotics.
  • Bacteria are less likely to become resistant to Solodyn (Minocycline) than other tetracycline antibiotics.
Downsides
No information currently available
  • It can make birth control pills less effective, so people should use barrier methods of birth control like condoms or diaphragms while on Solodyn (Minocycline).
  • Can stain your teeth, mouth, and gums if you're using the tablets, or your skin if you're using the topical version, but this is temporary.
Used for
Dosage forms
  • Cream, gel, or ointment
  • Pill
  • Extended release
  • Extended release capsule
Price
Lowest price near you
$57.15
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Lowest price near you
$98.31
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Reviews
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17 
53%
think this treatment is worth it
59%
think this treatment works well
18%
think this treatment is a hassle

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Side effects
The Differen (Adapalene) FDA package insert doesn’t have numbers about how common side effects are.
The Solodyn (Minocycline) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
No information currently available
  • Changes in teeth

    Age 8 years or younger

  • Decreased effectiveness of birth control pills

    Using oral birth control pills

  • Diarrhea from a superinfection (an infection that happens after, or in addition to, an earlier infection)

    Long antibiotic treatment period

  • Harm to fetus

    Women of childbearing age

See more detailed risks and warnings