Compare Diflucan vs. Vfend

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Diflucan (fluconazole)

Prescription only

Vfend (voriconazole)

Prescription only
Treats yeast and other fungal infections.

Diflucan (fluconazole) is a cheap and effective treatment for fungal infections.

3.9/ 5 average rating with 30 reviewsforDiflucan
Treats fungal infections.

Vfend (voriconazole) is effective at treating many different fungal infections, but it can cause blurry vision and make your eyes more sensitive to light.

Upsides
  • Available in a cheap generic version.
  • Single dose treatment for vaginal infections.
  • Available as a pill, liquid, or injection.
  • Vfend (voriconazole) is good for treating infections caused by many different types of fungi.
  • Available as a generic, and in both tablet and liquid form.
  • Vfend (voriconazole) is the antifungal drug of choice to treat Aspergillosis infection.
Downsides
  • Excessive use of alcohol while on this medicine can harm your liver.
  • Can interfere with how other medicines work, especially birth control pills.
  • Vfend (voriconazole) can cause blurry vision and sensitity to bright lights.
  • Vfend (voriconazole) cannot be taken with food.
  • Your skin may become more sensitive to the sun while taking Vfend (voriconazole). Make sure to use sunscreen or wear protective layers.
  • Vfend (voriconazole) has a lot of drug interactions.
  • Vfend (voriconazole) isn't absorbed in the same way by everyone, so you'll probably need to get regular blood tests while taking it.
Used for
  • Aspergillosis
  • Candidemia
  • Candidiasis of the esophagus
  • Disseminated candidiasis
  • Mycosis
Dosage forms
  • Pill
  • Liquid
  • Injection
  • Pill
  • Liquid
Price
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Reviews
30 reviews so far
73%
saidit'sworth it
60%
saiditworked well
20%
saidit'sa big hassle

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Side effects
5possible side effects
  • Headache
    2%
  • Skin Rash
    2%
  • Vomiting
    2%
  • Abdominal pain
    2%
  • Diarrhea
    2%
See more detailed side effects
11possible side effects
  • Abnormal vision
    19%
  • Fever
    6%
  • Nausea
    5%
  • Rash
    5%
  • Chills
    4%
  • Vomiting
    4%
  • Headache
    3%
  • Abnormal liver tests
    3%
  • Sensitivity to light
    2%
  • Fast heart rate
    2%
  • Hallucinations
    2%
See more detailed side effects
Risks and risk factors
  • Liver disease
  • Serious immediate allergic reaction
  • Skin rash
  • Use in pregnancy
See more detailed risks and warnings
  • Liver problems
    • Blood disorder
    • Liver disease
  • Abnormal vision or eye sensitivity
  • Abnormal heartbeat
    • QT prolongation
    • Arrhythmia
    • Drugs that cause prolonged QT interval
    • Abnormal electrolytes
  • Gallbladder problems
    • History of gallblader disease
    • People with severe kidney problems
  • Pancreas problems (pancreatitis)
  • Skin reaction to light
    • Children
See more detailed risks and warnings