Compare Digoxin vs. Imdur

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lanoxin
(digoxin)

Imdur
(isosorbide mononitrate)

Improves heart pumping. Digoxin is a good backup for treating heart failure symptoms, but it doesn't, by itself, lower your risk of death.Relieves chest pain. Isosorbide mononitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.
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Coupons for Digoxin
Best available price for 30 (125mcg) tablets of digoxin
Coupons for Imdur
Best available price for 60 (20mg) tablets of isosorbide-mononitrate
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.41Digoxin
Reviews for Digoxin
64%
of people (All ages) say Digoxin is worth it
43%
say it works well
31%
say it's a big hassle
Have you used Lanoxin (digoxin)?
Worth itNot sureNot worth it
Reviews for Imdur
47%
+17% better vs. Digoxin
29%
+14% better vs. Digoxin
32%
+1% better vs. Digoxin
Have you used Imdur (isosorbide mononitrate)?
Worth itNot sureNot worth it
Side effects
DigoxinImdur
  • Any side effect 20%
  • Dizziness 1%
  • Mental disturbances 4%
  • Nausea 1%
  • Diarrhea 3%
  • Death 1%
  • Side effects requiring hospitalization 1%
  • Abnormally fast heart beat 2%
  • Vomiting 2%
More Digoxin side effects »
  • Dizziness 4%
More Imdur side effects »
How it works
DigoxinImdur
Digoxin helps your heart work more efficiently. It makes your heart pump slower and stronger, which helps it get more blood and oxygen out to your body and organs.Isosorbide mononitrate is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.
Type of medication
DigoxinImdur
Prescription onlyPrescription only
Available as
DigoxinImdur
  • Pill
  • Liquid
  • Pill
  • Extended release
Used for
DigoxinImdur
Risk factors for serious side effects
DigoxinImdur
  • History of heart problems
  • Drug interactions
  • Wolff-Parkinson-White syndrome
  • Low body weight, advanced age, impaired renal function, electrolyte imbalances
  • Overactive or underactive thyroid
Detailed Lanoxin (digoxin) risks & warnings »
  • Concurrent use of erectile dysfunction medicine
  • Age 65 years or older
  • Alcohol use
  • Long term use
Detailed Imdur (isosorbide mononitrate) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
DigoxinImdur
  • Tell your doctor about other medicines you're taking to avoid drug interactions.
No interactions related info.
Alcohol
DigoxinImdur
No alcohol related info.
  • Don't drink alcohol while taking this medicine. It can make you really dizzy.
Upsides and benefits
DigoxinImdur
  • Used for some abnormal heart rhythms, and for heart failure that can't be controlled by other medications.
  • Relieves shortness of breath, and makes it easier to be active without having symptoms.
  • In studies, Digoxin lowered the risk of having to be admitted to the hospital for worsening heart failure.
  • Prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
Downsides and risks
DigoxinImdur
  • For heart failure, relieves symptoms, but does not lower the risk of death. That's why it's usually used together with other heart failure medicines that do lower the risk of death.
  • Requires blood tests, especially during the first few weeks of treatment.
  • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
  • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
Tips from our pharmacists for people taking the medication
DigoxinImdur
  • Take it at the same time every day.
  • Drink plenty of water while taking this medicine.
  • Requires routine blood tests to make sure you have the right amount of Digoxin in your body.
  • Tell your doctor about other medicines you're taking to avoid drug interactions.
  • Can cause headaches, dizziness, lightheadedness, or fainting. Headache can be a sign that the medicine is working.
  • Don't drink alcohol while taking this medicine. It can make you really dizzy.
  • Tell your doctor if you're taking any medicine for erectile dysfunction.
  • Don't stop taking this medicine suddenly.
Learn more
More about DigoxinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lanoxin (digoxin)?
Worth itNot sureNot worth it
More about ImdurSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Imdur (isosorbide mononitrate)?
Worth itNot sureNot worth it