Compare Dilaudid vs. Morphine Sulfate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dilaudid (Hydromorphone)

Prescription only
Treats moderate to severe pain.

Dilaudid (Hydromorphone) is a fast-acting, potent medication that treats problems needing strong pain relief.

5.6/ 7 average rating with 51 reviewsforDilaudid
Treats severe pain.

Ms Contin (Morphine Sulfate) provides good long-term pain control without the need to take medicine frequently, but watch out for constipation.

4.8/ 7 average rating with 541 reviewsforMorphine Sulfate
Upsides
  • Works well to relieve moderate to severe pain.
  • Dilaudid (Hydromorphone) is stronger than morphine and works quicker than other pain medications.
  • It doesn't cause as many side effects, like nausea and rashes, as morphine does.
  • It's available as fast-acting tablets, extended-release tablets, and as a liquid.
  • Provides longer relieve for moderate to severe pain to improve quality of life.
  • Good for chronic pain that requires around-the-clock relief.
  • Might have fewer side effects than other opioid pain relievers.
Downsides
  • People with breathing problems like asthma and COPD need to be monitored very closely if taking Dilaudid (Hydromorphone).
  • Dilaudid (Hydromorphone) isn't usually used for elderly or frail patients.
  • Dizziness and drowsiness are common when taking Dilaudid (Hydromorphone), but your body may adjust over time.
  • Everyone tends to get constipation while on this, so you'll need to stay hydrated and may need to take a stool softener medication.
  • Long-term use will likely cause physical dependence.
  • Must be weaned slowly off the medicine after using it longer than 2 weeks.
  • Doesn't work for as-needed or quick pain relief.
  • Dizziness and drowsiness is common, but your body may adjust.
  • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Ms Contin (Morphine Sulfate) if you need.
  • Long term use will likely cause physical dependence.
  • Must be weaned slowly off the medicine after use longer than 2 weeks.
Used for
Dosage forms
  • Pill
  • Extended release
  • Oral solution
  • Suppository
  • Pill
  • Extended release
  • Oral solution
  • Liquid
  • Suppository
Price
Lowest price near you
$7.72
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$201.89
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Reviews
51 
78%
think this treatment is worth it
65%
think this treatment works well
10%
think this treatment is a hassle

Have you used Dilaudid (Hydromorphone)?

Leave a review
541 
55%
think this treatment is worth it
43%
think this treatment works well
20%
think this treatment is a hassle

Have you used Ms Contin (Morphine Sulfate)?

Leave a review
Side effects
10possible side effects
  • Constipation
    31%
  • Nausea
    28%
  • Headache
    15%
  • Somnolence
    14%
  • Asthenia/fatigue
    12%
  • Dizziness
    11%
  • Diarrhea
    11%
  • Pruritus
    8%
  • Insomnia
    8%
  • Hyperhydrosis
    7%
See more detailed side effects
The Ms Contin (Morphine Sulfate) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Death from lack of oxygen to the body (respiratory depression)

    Current use of medicine that affects liver enzyme CYP 3A4

    ...and 4 more risk factors

  • Death from overdose

    Children age 18 and younger

  • Death in newborn babies from opioid withdrawal (Neonatal opioid withdrawal syndrome)

    Long-term use during pregnancy

  • Tolerance, dependence, and addiction

    Taking more than the prescribed dose

    ...and 2 more risk factors

  • Driving impairment

    Taking with alcohol

    ...and 2 more risk factors

  • Low blood pressure

    Age 65 years or older

See more detailed risks and warnings
  • Death from lack of oxygen to the body (respiratory depression)

    Current use of medicine that affects liver enzyme CYP 3A4

    ...and 4 more risk factors

  • Death from overdose

    Children age 18 and younger

  • Death in newborn babies from opioid withdrawal (Neonatal opioid withdrawal syndrome)

    Long-term use during pregnancy

  • Tolerance, dependence, and addiction

    Taking more than the prescribed dose

    ...and 2 more risk factors

  • Driving impairment

    Taking with alcohol

    ...and 2 more risk factors

  • Low blood pressure

    Age 65 years or older

See more detailed risks and warnings