Compare Dilaudid vs. Opana

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dilaudid
(Hydromorphone)

Opana
(Oxymorphone)

Treats moderate to severe pain. Dilaudid (Hydromorphone) is a fast-acting, potent medication that treats problems needing strong pain relief.Coming soon.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.65625Dilaudid
Reviews for Dilaudid (Hydromorphone)
75%
of people say Dilaudid (Hydromorphone) is worth it
72%
say it works well
9%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
DilaudidOpana
  • Joint pain 4%
  • Weight decreased 1%
More Dilaudid side effects »

We haven’t found good data for Opana side effects.

FDA side effect reports for Opana »
How it works
DilaudidOpana
Dilaudid (Hydromorphone) is an opioid medicine (similar to morphine) that works in the brain to lower pain perception.Coming soon.
Type of medication
DilaudidOpana
Pain reliever
Opioid
Prescription only
Coming soon.
Available as
DilaudidOpana
  • Pill
  • Extended release
  • Oral solution
  • Suppository
  • Pill
Used for (click to learn more)
DilaudidOpana
  • Anesthesia; Adjunct Anxiety
Risk factors for serious side effects
DilaudidOpana
  • Current use of medicine that affects liver enzyme CYP 3A4
  • Age 65 or greater
  • Higher dose
  • People with not enough thyroid hormones
  • History of lung problems
  • Children age 18 and younger
  • Long-term use during pregnancy
  • Taking more than the prescribed dose
  • Long-term use
  • History of drug abuse
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 or greater
  • Age 65 years or older
Detailed Dilaudid (Hydromorphone) risks & warnings »
Coming soon.
Pregnancy category
DilaudidOpana
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
  • Never use alcohol when taking Dilaudid (Hydromorphone).
No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
  • Dizziness and drowsiness are common when taking Dilaudid (Hydromorphone), but your body may adjust over time.
  • Dilaudid (Hydromorphone) will cause drowsiness, so be really careful if you're taking other meds that also cause drowsiness, such as antidepressives, antianxiety meds, or muscle relaxants.
No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
DilaudidOpana
  • Works well to relieve moderate to severe pain.
  • Dilaudid (Hydromorphone) is stronger than morphine and works quicker than other pain medications.
  • It doesn't cause as many side effects, like nausea and rashes, as morphine does.
  • It's available as fast-acting tablets, extended-release tablets, and as a liquid.
Coming soon.
Downsides and risks
DilaudidOpana
  • People with breathing problems like asthma and COPD need to be monitored very closely if taking Dilaudid (Hydromorphone).
  • Dilaudid (Hydromorphone) isn't usually used for elderly or frail patients.
  • Dizziness and drowsiness are common when taking Dilaudid (Hydromorphone), but your body may adjust over time.
  • Everyone tends to get constipation while on this, so you'll need to stay hydrated and may need to take a stool softener medication.
  • Long-term use will likely cause physical dependence.
  • Must be weaned slowly off the medicine after using it longer than 2 weeks.
Coming soon.
Tips from our pharmacists for people taking the medication
DilaudidOpana
  • Dilaudid (Hydromorphone) is usually taken for a short time. If you take it longer than 2 weeks, you'll need to lower your dose slowly to get off it since stopping suddenly can cause withdrawal symptoms.
  • Usually works within 30 minutes.
  • Dilaudid (Hydromorphone) will cause drowsiness, so be really careful if you're taking other meds that also cause drowsiness, such as antidepressives, antianxiety meds, or muscle relaxants.
  • Never use alcohol when taking Dilaudid (Hydromorphone).
  • It's very important to keep Dilaudid (Hydromorphone) away from children, since it can stop them from breathing.
Coming soon.
Learn more
More about DilaudidSide effectsReviews & ratingsAlternativesFDA package insert
More about OpanaSide effectsReviews & ratingsFDA package insert