Compare Dilaudid vs. Opana

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dilaudid
(hydromorphone)

Opana
(oxymorphone)

Treats moderate to severe pain. Dilaudid (Hydromorphone) is a fast-acting, potent medication that treats problems needing strong pain relief.Coming soon.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.59Dilaudid
Reviews for Dilaudid
78%
of people (All ages) say Dilaudid is worth it
65%
say it works well
10%
say it's a big hassle
Have you used Dilaudid (hydromorphone)?
Worth itNot sureNot worth it

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Have you used Opana (oxymorphone)?
Worth itNot sureNot worth it
Side effects
DilaudidOpana
  • Constipation 15%
  • Nausea 12%
  • Somnolence 9%
  • Headache 8%
  • Vomiting 2%
  • Arthralgia 4%
  • Pruritus 5%
  • Insomnia 1%
  • Asthenia/fatigue 12%
  • Dizziness 11%
More Dilaudid side effects »

We haven’t found good data for Opana side effects.

FDA side effect reports for Opana »
How it works
DilaudidOpana
Dilaudid (Hydromorphone) is an opioid medicine (similar to morphine) that works in the brain to lower pain perception.Coming soon.
Type of medication
DilaudidOpana
Prescription only
Available as
DilaudidOpana
  • Pill
  • Extended release
  • Oral solution
  • Suppository
  • Pill
Used for
DilaudidOpana
  • Anesthesia Adjunct Anxiety
Risk factors for serious side effects
DilaudidOpana
  • Current use of medicine that affects liver enzyme CYP 3A4
  • Age 65 or greater
  • Higher dose
  • People with not enough thyroid hormones
  • History of lung problems
Detailed Dilaudid (hydromorphone) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    DilaudidOpana
    • Never use alcohol when taking Dilaudid (Hydromorphone).
    No alcohol related info.
    Pain
    DilaudidOpana
    • Works well to relieve moderate to severe pain.
    No pain related info.
    Sleep
    DilaudidOpana
    • Dilaudid (Hydromorphone) will cause drowsiness, so be really careful if you're taking other meds that also cause drowsiness, such as antidepressives, antianxiety meds, or muscle relaxants.
    • Dizziness and drowsiness are common when taking Dilaudid (Hydromorphone), but your body may adjust over time.
    No sleep related info.
    Upsides and benefits
    DilaudidOpana
    • Works well to relieve moderate to severe pain.
    • Dilaudid (Hydromorphone) is stronger than morphine and works quicker than other pain medications.
    • It doesn't cause as many side effects, like nausea and rashes, as morphine does.
    • It's available as fast-acting tablets, extended-release tablets, and as a liquid.
    Coming soon
    Downsides and risks
    DilaudidOpana
    • People with breathing problems like asthma and COPD need to be monitored very closely if taking Dilaudid (Hydromorphone).
    • Dilaudid (Hydromorphone) isn't usually used for elderly or frail patients.
    • Dizziness and drowsiness are common when taking Dilaudid (Hydromorphone), but your body may adjust over time.
    • Everyone tends to get constipation while on this, so you'll need to stay hydrated and may need to take a stool softener medication.
    • Long-term use will likely cause physical dependence.
    • Must be weaned slowly off the medicine after using it longer than 2 weeks.
    Coming soon
    Tips from our pharmacists for people taking the medication
    DilaudidOpana
    • Dilaudid (Hydromorphone) is usually taken for a short time. If you take it longer than 2 weeks, you'll need to lower your dose slowly to get off it since stopping suddenly can cause withdrawal symptoms.
    • Usually works within 30 minutes.
    • Dilaudid (Hydromorphone) will cause drowsiness, so be really careful if you're taking other meds that also cause drowsiness, such as antidepressives, antianxiety meds, or muscle relaxants.
    • Never use alcohol when taking Dilaudid (Hydromorphone).
    • It's very important to keep Dilaudid (Hydromorphone) away from children, since it can stop them from breathing.
    Coming soon
    Learn more
    More about DilaudidSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Dilaudid (hydromorphone)?
    Worth itNot sureNot worth it
    More about OpanaSide effectsReviews & ratingsFDA package insert
    Have you used Opana (oxymorphone)?
    Worth itNot sureNot worth it