Compare Diltiazem vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cardizem
(diltiazem)

Coreg
(carvedilol)

Lowers blood pressure and controls heart rate. Diltiazem works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.71Diltiazem
Reviews for Diltiazem
52%
of people (All ages) say Diltiazem is worth it
49%
say it works well
16%
say it's a big hassle
105 reviews
Have you used Cardizem (diltiazem)?
Worth itNot sureNot worth it
Reviews for Coreg
53%
-1% worse vs. Diltiazem
46%
+3% better vs. Diltiazem
18%
+2% better vs. Diltiazem
406 reviews
Have you used Coreg (carvedilol)?
Worth itNot sureNot worth it
Side effects
DiltiazemCoreg
  • Edema 5%
  • Headache 5%
  • Dizziness 4%
  • Asthenia 3%
  • First degree AV block 2%
  • Bradycardia 2%
More Diltiazem side effects »
  • Dizziness 13%
  • Fatigue 2%
  • Hyperglycemia 4%
  • Diarrhea 6%
  • Weight increase 3%
  • Nausea 4%
  • Bradycardia 8%
  • Hypotension 6%
  • Headache 1%
More Coreg side effects »
How it works
DiltiazemCoreg
Diltiazem is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
DiltiazemCoreg
Prescription onlyPrescription only
Available as
DiltiazemCoreg
  • Pill
  • Extended release
  • Extended release capsule
  • Pill
  • Extended release
Used for
DiltiazemCoreg
Risk factors for serious side effects
DiltiazemCoreg
  • Taking digoxin or beta-blockers at the same time
  • History of liver disease
Detailed Cardizem (diltiazem) risks & warnings »
  • Abrupt discontinuation of Coreg (Carvedilol)
  • Congestive heart failure
  • Increasing the dose of Coreg (Carvedilol)
  • Diabetes
  • Major surgery requiring anesthesia
Detailed Coreg (carvedilol) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
DiltiazemCoreg
  • Interacts with the cholesterol medicine Simvastatin.
No interactions related info.
Alcohol
DiltiazemCoreg
  • Not a good medication for you if you drink alcohol.
No alcohol related info.
Food
DiltiazemCoreg
No food related info.
  • Take it with food.
  • You have to take Carvedilol with food.
Kidneys and liver
DiltiazemCoreg
  • There have been reports of liver damage within the first eight weeks of Cardizem (Diltiazem), particularly if you have a history of liver disease. Your doctor may monitor your liver.
No kidneys and liver related info.
Upsides and benefits
DiltiazemCoreg
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
Downsides and risks
DiltiazemCoreg
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Diltiazem than men.
  • You can't miss doses. Stopping Diltiazem suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Some brands of Diltiazem have to be taken with food, so listen carefully for instructions from your doctor or pharmacist.
  • Not a good medication for you if you drink alcohol.
  • You have to take Carvedilol with food.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
DiltiazemCoreg
  • Can cause dizziness or fatigue in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Interacts with the cholesterol medicine Simvastatin.
  • Can cause ankle or foot swelling.
  • Can cause gum overgrowth. Ask your dentist to check for this side effect.
  • Take it with food.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause fatigue and erectile dysfunction.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
Learn more
More about DiltiazemSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Cardizem (diltiazem)?
Worth itNot sureNot worth it
More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Coreg (carvedilol)?
Worth itNot sureNot worth it