Compare Diltiazem vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cardizem
(Diltiazem)

Coreg
(Carvedilol)

Lowers blood pressure and controls heart rate. Diltiazem works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.757575757575758Diltiazem
Reviews for Cardizem (Diltiazem)
53%
of people say Cardizem (Diltiazem) is worth it
48%
say it works well
16%
say it's a big hassle
Reviews for Coreg (Carvedilol)
54%
+1% vs. Cardizem (Diltiazem)
46%
2% vs. Cardizem (Diltiazem)
18%
2% vs. Cardizem (Diltiazem)
Side effects
DiltiazemCoreg
  • Abnormally slow heartbeat 2%
More Diltiazem side effects »
  • Dizziness 13%
  • Abnormally slow heartbeat 7%
  • Low blood pressure 6%
  • Diarrhea 6%
  • High blood sugar 4%
  • Nausea 4%
  • Vision abnormal 3%
  • Fainting 3%
  • Muscle weakness 2%
  • Edema dependent 2%
More Coreg side effects »
How it works
DiltiazemCoreg
Diltiazem is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
DiltiazemCoreg
Antihypertensive
Calcium channel blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Available as
DiltiazemCoreg
  • Pill
  • Extended release
  • Extended release capsule
  • Pill
  • Extended release
Used for (click to learn more)
DiltiazemCoreg
Risk factors for serious side effects
DiltiazemCoreg
    • Taking digoxin or beta-blockers at the same time
    • History of liver disease
    Detailed Cardizem (Diltiazem) risks & warnings »
    • Abrupt discontinuation of Coreg (Carvedilol)
        • Congestive heart failure
        • Increasing the dose of Coreg (Carvedilol)
        • Diabetes
        • Major surgery requiring anesthesia
          Detailed Coreg (Carvedilol) risks & warnings »
          Pregnancy category
          DiltiazemCoreg
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          • Not a good medication for you if you drink alcohol.
          No specific alcohol-related info.
          Food
          • Some brands of Diltiazem have to be taken with food, so listen carefully for instructions from your doctor or pharmacist.
          • You have to take Carvedilol with food.
          • Take it with food.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          No specific sleep-related info.No specific sleep-related info.
          Weight
          No specific weight-related info.
          • You may notice worsening symptoms of heart failure if your prescriber decides to increase your dosage of Coreg (Carvedilol). Tell your doctor if you noticed increased swelling around your legs or ankles, sudden weight gain or sudden shortness of breath as they may make changes to your medications for heart failure.
          Upsides and benefits
          DiltiazemCoreg
          • A first-choice blood pressure treatment for many people.
          • Calcium channel blockers work especially well for African Americans to lower blood pressure.
          • You can take it alone or with other medicines to help lower blood pressure.
          • Lowers the risk of heart attack and stroke.
          • Prevents heart-related chest pain (angina) if you take it regularly.
          • Treats certain abnormal heart rhythms.
          • A first-choice treatment to prevent chest pain (angina).
          • A first-choice treatment for heart failure and heart attack.
          • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
          Downsides and risks
          DiltiazemCoreg
          • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
          • Women are more likely to have side effects (especially swelling) from Diltiazem than men.
          • You can't miss doses. Stopping Diltiazem suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          • Some brands of Diltiazem have to be taken with food, so listen carefully for instructions from your doctor or pharmacist.
          • Not a good medication for you if you drink alcohol.
          • You have to take Carvedilol with food.
          • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
          • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
          • Can hide symptoms of low blood sugar if you're diabetic.
          • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
          Tips from our pharmacists for people taking the medication
          DiltiazemCoreg
          • Can cause dizziness or fatigue in the first few days.
          • Interacts with the cholesterol medicine Simvastatin.
          • Can cause ankle or foot swelling.
          • Can cause gum overgrowth. Ask your dentist to check for this side effect.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          • Take it with food.
          • Can cause dizziness in the first few days.
          • Can cause fatigue and erectile dysfunction.
          • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
          • Don't stop taking this medicine suddenly.
          • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
          Learn more
          More about DiltiazemSide effectsReviews & ratingsAlternativesFDA package insert
          More about CoregSide effectsReviews & ratingsAlternativesFDA package insert