Compare Diltiazem vs. Nifedipine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cardizem (Diltiazem)

Prescription only

Procardia (Nifedipine)

Prescription only
Lowers blood pressure and controls heart rate.

Diltiazem works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.

4.7/ 7 average rating with 105 reviewsforDiltiazem
Lowers blood pressure and controls heart rate.

Nifedipine works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding grapefruit. You can't miss doses, and you might get persistent swelling.

3.7/ 7 average rating with 26 reviewsforNifedipine
Upsides
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
Downsides
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Diltiazem than men.
  • You can't miss doses. Stopping Diltiazem suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Some brands of Diltiazem have to be taken with food, so listen carefully for instructions from your doctor or pharmacist.
  • Not a good medication for you if you drink alcohol.
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Nifedipine than men.
  • You can't miss doses. Stopping Nifedipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not a good medication for you if you love grapefruit. It can make Nifedipine have a stronger effect on your blood pressure.
Used for
Dosage forms
  • Pill
  • Extended release
  • Extended release capsule
  • Pill
  • Extended release
Price
No pricing information available
Lowest price near you
$32.05
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Reviews
105 
52%
think this treatment is worth it
49%
think this treatment works well
16%
think this treatment is a hassle

Have you used Cardizem (Diltiazem)?

Leave a review
26 
42%
think this treatment is worth it
31%
think this treatment works well
46%
think this treatment is a hassle

Have you used Procardia (Nifedipine)?

Leave a review
Side effects
6possible side effects
  • Edema
    5%
  • Headache
    5%
  • Dizziness
    4%
  • Asthenia
    3%
  • First degree AV block
    2%
  • Bradycardia
    2%
See more detailed side effects
10possible side effects
  • Dizziness, lightheadedness, giddiness
    27%
  • Flushing
    25%
  • Headache
    23%
  • Weakness
    12%
  • Nausea, heartburn
    11%
  • Muscle cramps, tremor
    8%
  • Peripheral edema
    7%
  • Nervousness, mood changes
    7%
  • Palpitation
    7%
  • Dyspnea, cough, wheezing
    6%
See more detailed side effects
Risks and warnings
  • Abnormally slow heart rate

    Taking digoxin or beta-blockers at the same time

  • Sudden liver disease

    History of liver disease

See more detailed risks and warnings
  • Intestinal blockage

    Taking anti-inflammatories, acid reducers in the stomach, anticholinergics, laxatives, levothyroxine

    ...and 1 more risk factors

  • Chest pain

    Taking beta-blockers

    ...and 1 more risk factors

  • Liver damage/jaundice

    History of cirrhosis

  • Congestive heart failure

    History of tight aortic stenosis

    ...and 1 more risk factors

  • Heart attack or increased chest pain

    Obstructive coronary artery disease

See more detailed risks and warnings