Compare Diltiazem vs. felodipine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cardizem (Diltiazem)

Prescription only

Plendil (felodipine)

Prescription only
Lowers blood pressure and controls heart rate.

Diltiazem works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.

4.7/ 7 average rating with 105 reviewsforDiltiazem
Lowers blood pressure.

Plendil (felodipine) works well to lower blood pressure, but it may cause swelling in your arms and legs at higher doses.

Upsides
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
  • Plendil (felodipine) is a good option for people with high blood pressure.
  • Calcium channel blockers sometimes work better for people of African descent than other blood pressure lowering drugs.
Downsides
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Diltiazem than men.
  • You can't miss doses. Stopping Diltiazem suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Some brands of Diltiazem have to be taken with food, so listen carefully for instructions from your doctor or pharmacist.
  • Not a good medication for you if you drink alcohol.
  • Plendil (felodipine) may not work as well as other calcium channel blockers.
  • It can lead to more swelling in your arms and legs when taken at higher doses.
  • You can't miss doses. Stopping Plendil (felodipine) could cause a sudden spike in blood pressure.
  • Plendil (felodipine) can't be crushed or cut into two.
Used for
Dosage forms
  • Pill
  • Extended release
  • Extended release capsule
  • Extended release
No pricing information available
No pricing information available
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Reviews
105 
52%
think this treatment is worth it
49%
think this treatment works well
16%
think this treatment is a hassle

Have you used Cardizem (Diltiazem)?

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Side effects
6possible side effects
  • Edema
    5%
  • Headache
    5%
  • Dizziness
    4%
  • Asthenia
    3%
  • First degree AV block
    2%
  • Bradycardia
    2%
See more detailed side effects
8possible side effects
  • Headache
    10%
  • Swelling
    9%
  • Flushing
    5%
  • Racing heart beat
    4%
  • Weakness
    3%
  • Dizziness
    3%
  • Nausea
    2%
  • Colds or flu
    2%
See more detailed side effects
Risks and warnings
  • Abnormally slow heart rate

    Taking digoxin or beta-blockers at the same time

  • Sudden liver disease

    History of liver disease

See more detailed risks and warnings
  • Low blood pressure

    Over age 65

  • Heart failure

    Taking in combination with a beta-blocker

  • Special dosing requirements

    Liver disease

    ...and 1 more risk factors

  • Swelling in arms and legs

    History of heart failure

    ...and 1 more risk factors

See more detailed risks and warnings