Compare Diltiazem vs. Plendil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cardizem
(Diltiazem)

Plendil
(Felodipine)

Lowers blood pressure and controls heart rate. Diltiazem works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling.Coming soon.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.757575757575758Diltiazem
Reviews for Cardizem (Diltiazem)
53%
of people say Cardizem (Diltiazem) is worth it
48%
say it works well
16%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
DiltiazemPlendil
  • Abnormally slow heartbeat 2%
More Diltiazem side effects »

We haven’t found good data for Plendil side effects.

FDA side effect reports for Plendil »
How it works
DiltiazemPlendil
Diltiazem is a calcium channel blocker. It lowers blood pressure by slowing your heart rate and relaxing your blood vessels. Your heart gets more oxygen and doesn't have to work as hard to pump, which can relieve chest pain.Coming soon.
Type of medication
DiltiazemPlendil
Antihypertensive
Calcium channel blocker
Prescription only
Coming soon.
Available as
DiltiazemPlendil
  • Pill
  • Extended release
  • Extended release capsule
  • Extended release
Used for (click to learn more)
DiltiazemPlendil
  • Hypertension
Risk factors for serious side effects
DiltiazemPlendil
    • Taking digoxin or beta-blockers at the same time
    • History of liver disease
    Detailed Cardizem (Diltiazem) risks & warnings »
    Coming soon.
    Pregnancy category
    DiltiazemPlendil
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    • Not a good medication for you if you drink alcohol.
    No specific alcohol-related info.
    Food
    • Some brands of Diltiazem have to be taken with food, so listen carefully for instructions from your doctor or pharmacist.
    No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    DiltiazemPlendil
    • A first-choice blood pressure treatment for many people.
    • Calcium channel blockers work especially well for African Americans to lower blood pressure.
    • You can take it alone or with other medicines to help lower blood pressure.
    • Lowers the risk of heart attack and stroke.
    • Prevents heart-related chest pain (angina) if you take it regularly.
    • Treats certain abnormal heart rhythms.
    Coming soon.
    Downsides and risks
    DiltiazemPlendil
    • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
    • Women are more likely to have side effects (especially swelling) from Diltiazem than men.
    • You can't miss doses. Stopping Diltiazem suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    • Some brands of Diltiazem have to be taken with food, so listen carefully for instructions from your doctor or pharmacist.
    • Not a good medication for you if you drink alcohol.
    Coming soon.
    Tips from our pharmacists for people taking the medication
    DiltiazemPlendil
    • Can cause dizziness or fatigue in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Interacts with the cholesterol medicine Simvastatin.
    • Can cause ankle or foot swelling.
    • Can cause gum overgrowth. Ask your dentist to check for this side effect.
    Coming soon.
    Learn more
    More about DiltiazemSide effectsReviews & ratingsAlternativesFDA package insert
    More about PlendilSide effectsReviews & ratingsFDA package insert