Compare Diovan vs. Lisinopril

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Diovan
(valsartan)

Zestril
(lisinopril)

Lowers blood pressure. Diovan (Valsartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.Lowers blood pressure. Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.
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Prices and coupon for 30 (160mg) tablets of valsartan
Coupons for
Prices and coupon for 30 (20mg) tablets of lisinopril
Reviews & ratings
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Filter group. All currently selected
5.19Diovan
Reviews for Diovan (valsartan)
65%
of people (All ages) say Diovan (valsartan) is worth it
54%
say it works well
15%
say it's a big hassle
431 reviews
Have you used Diovan (valsartan)?
Worth itNot sureNot worth it
Reviews for Zestril (lisinopril)
61%
-4% worse vs. Diovan (valsartan)
51%
-3% worse vs. Diovan (valsartan)
14%
+1% better vs. Diovan (valsartan)
687 reviews
Have you used Zestril (lisinopril)?
Worth itNot sureNot worth it
Side effects
DiovanLisinopril
  • Dizziness 2%
  • Cough 1%
  • Viral infection 1%
  • Fatigue 1%
  • Abdominal pain 1%
  • Low blood pressure 5%
  • Diarrhea 1%
  • Joint pain 1%
  • Back pain 1%
  • Dizziness, postural 1%
More Diovan side effects »
  • Headache 4%
  • Dizziness 4%
  • Cough 3%
  • Low blood pressure 4%
  • Chest pain 2%
  • Kidney damage 10%
  • Fainting 7%
  • High potassium 6%
More Lisinopril side effects »
How it works
DiovanLisinopril
Diovan (Valsartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Zestril (lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
DiovanLisinopril
Prescription only
Prescription only
Available as
DiovanLisinopril
  • Pill
  • Pill
  • Liquid
Used for
DiovanLisinopril
Risk factors for serious side effects
DiovanLisinopril
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Diovan (valsartan) risks & warnings »
  • Women of childbearing age
    • African descent
    • Current kidney problems
    • Medicines that increase potassium
    • Use of salt substitutes
    • History of kidney problems
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
    Detailed Zestril (lisinopril) risks & warnings »
    Pregnancy

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Kidneys and liver
    DiovanLisinopril
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • You'll need to have blood tests done to check your kidney function.
    Upsides and benefits
    DiovanLisinopril
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • Very cheap drug, and comes available as a liquid for children over 6 years of age.
    Downsides and risks
    DiovanLisinopril
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Zestril (lisinopril) isn't safe to use if you're pregnant.
    • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
    Tips from our pharmacists for people taking the medication
    DiovanLisinopril
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Don't take it if you're pregnant.
    • Can cause dizziness the first few days you're taking it.
    • Check your blood pressure about 1 week after starting Zestril (lisinopril), and tell your doctor if it hasn't improved.
    • Let your doctor know about any dizziness, tiredness, cough, or throat irritation that doesn't go away.
    • You'll need to have blood tests done to check your kidney function.
    • Don't take Zestril (lisinopril) if you're pregnant.
    Learn more
    More about DiovanSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Diovan (valsartan)?
    Worth itNot sureNot worth it
    More about LisinoprilSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Zestril (lisinopril)?
    Worth itNot sureNot worth it