Compare Diovan vs. Toprol XL

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Diovan
(Valsartan)

Toprol Xl
(Metoprolol Succinate)

Lowers blood pressure. Diovan (Valsartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.Lowers blood pressure and controls heart rate. Toprol Xl (Metoprolol Succinate) is good for controlling chest pain and treating heart failure and heart attack. You can't miss doses.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.1850117096018735Diovan
Reviews for Diovan (Valsartan)
65%
of people say Diovan (Valsartan) is worth it
54%
say it works well
15%
say it's a big hassle
Reviews for Toprol Xl (Metoprolol Succinate)
60%
5% vs. Diovan (Valsartan)
55%
+1% vs. Diovan (Valsartan)
13%
+2% vs. Diovan (Valsartan)
Side effects
DiovanToprol XL
  • Dizziness 8%
  • Low blood pressure 5%
  • Diarrhea 1%
  • High blood potassium 1%
  • Dizziness, postural 1%
  • Abdominal pain 1%
  • Positional low blood pressuren, postural 1%
  • Cough 1%
  • Back pain 1%
  • Joint pain 1%
More Diovan side effects »
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • Heart block 3%
More Toprol XL side effects »
How it works
DiovanToprol XL
Diovan (Valsartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Toprol Xl (Metoprolol Succinate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
DiovanToprol XL
Antihypertensive
Angiotensin receptor blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Available as
DiovanToprol XL
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
DiovanToprol XL
Risk factors for serious side effects
DiovanToprol XL
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Diovan (Valsartan) risks & warnings »
  • Diabetes
    • Coronary artery disease
    • Heart failure
    • Major surgery requiring anesthesia
    • History of asthma
    Detailed Toprol Xl (Metoprolol Succinate) risks & warnings »
    Pregnancy category
    DiovanToprol XL
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Requires routine blood tests to check kidney function.
    No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    DiovanToprol XL
    • A first-choice blood pressure treatment for many people.
    • Lowers the risk of heart attack and stroke.
    • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
    • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
    • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
    • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
    • A first-choice treatment for heart failure. May prevent long-term heart damage.
    • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
    • Toprol XL is the extended release version of Lopressor.
    Downsides and risks
    DiovanToprol XL
    • Requires a yearly blood test to see how the medicine is affecting your body.
    • Not safe to use if you're pregnant.
    • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
    • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
    • Can hide symptoms of low blood sugar if you're diabetic.
    • You can't miss doses. Stopping Toprol XL suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
    Tips from our pharmacists for people taking the medication
    DiovanToprol XL
    • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Don't take it if you're pregnant.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Can cause fatigue and headache.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Don't stop taking this medicine suddenly.
    • Extended release version. Also comes in immediate release called Lopressor (metoprolol tartrate).
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    Learn more
    More about DiovanSide effectsReviews & ratingsAlternativesFDA package insert
    More about Toprol XLSide effectsReviews & ratingsAlternativesFDA package insert