Compare Dipentum vs. Sulfasalazine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dipentum (olsalazine)

Prescription only
Treats ulcerative colitis, a chronic inflammatory condition involving your digestive system.

Dipentum (olsalazine) controls ulcerative colitis with other medicines, but you can't use it if you have a flare-up.

Reduces inflammation.

Azulfidine (Sulfasalazine) is used to treat moderate to severe inflammatory bowel conditions. It's also used with other medicines to treat rheumatoid arthritis.

Upsides
  • Dipentum (olsalazine) is one of the few medicines you can take for ulcerative colitis by mouth.
  • Can stop your symptoms from coming back so often.
  • Take Dipentum (olsalazine) by itself or with rectal formulation. If you have tried taking other rectal formulations without success, taking Dipentum (olsalazine) with rectal formulation may provide relief.
  • Can slow down the progression of your rheumatoid arthritis.
  • Helps control your stomach problems if you're taking it for ulcerative colitis.
Downsides
  • Can be only used if you don't like enemas or similar dosage forms, but Dipentum (olsalazine) doesn't work as fast and you would have to take more pills.
  • Dipentum (olsalazine) can cause more side effects than other pills for ulcerative colitis. Talk to your doctor about oral alternatives with less side effects.
  • Requires constant lab monitoring, at least every other week when you first start using it.
  • Not a good option if you have kidney or liver disease.
  • If you're allergic to sulfa drugs or aspirin, you can't take Azulfidine (Sulfasalazine).
  • Can interfere with lab test results, so let your doctor know if you're taking this drug.
  • Interacts with a lot of different drugs and can also cause many side effects.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
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Reviews
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Side effects
11possible side effects
  • Diarrhea
    11%
  • Abdominal pain and cramps
    10%
  • Nausea
    5%
  • Headache
    5%
  • Indigestion
    4%
  • Joint pain
    4%
  • Bloating
    2%
  • Fatigue and drowsiness
    2%
  • Depression
    2%
  • Rash
    2%
  • Upper respiratory infection
    2%
See more detailed side effects
8possible side effects
  • Nausea
    19%
  • Stomach problems
    13%
  • Rash
    13%
  • Headache
    9%
  • Stomach pain
    8%
  • Vomiting
    8%
  • Fever
    5%
  • Dizziness
    4%
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Risks and risk factors
  • Allergic reaction
    • Allergy to salicylates
  • Worsened asthma or allergies
    • History of severe allergies
    • History of asthma
  • Kidney problems
    • History of kidney disease
  • Liver problems
    • History of liver disease
  • Drug interactions
    • Taking Lovenox, Fragmin, Heparinoids, Coumadin, Purinethol, and/or Tabloid
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  • Kidney, liver, or blood problems
  • Serious skin reactions
  • Serious allergic reactions
  • Serious infections
  • Drug interactions
See more detailed risks and warnings