Compare dorzolamide timolol vs. Simbrinza

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Cosopt
(Dorzolamide / Timolol)

Simbrinza
(Brinzolamide / Brimonidine)

lowers eye pressure An effective two medicine combination that is used when one medication is not effective, and you are looking for ease of using both medications in one drop. Lowering eye pressure can prevent the onset of glaucoma.lowers eye pressure Simbrinza ia an effective two medicine combination that is used when one medication alone is not effective, and you are looking for ease of using both medications in one drop.
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Reviews & ratings
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Side effects
dorzolamide timololSimbrinza

We haven’t found good data for dorzolamide timolol side effects.

FDA side effect reports for dorzolamide timolol »

We haven’t found good data for Simbrinza side effects.

FDA side effect reports for Simbrinza »
How it works
dorzolamide timololSimbrinza
[name_common decreases the production of fluids within the eye, and increases the flow of fluids out of the eye.Simbrinza decreases the production of fluids within the eye, and increases the flow of fluids out of the eye.
Type of medication
dorzolamide timololSimbrinza
Coming soon.
Coming soon.
Available as
dorzolamide timololSimbrinza
  • Eye drops
  • Eye drops
Used for (click to learn more)
dorzolamide timololSimbrinza
  • Ocular hypertension
  • Ocular hypertension Open-angle glaucoma
Risk factors for serious side effects
dorzolamide timololSimbrinza
Coming soon.Coming soon.
Pregnancy category
dorzolamide timololSimbrinza
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
No specific alcohol-related info.No specific alcohol-related info.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
dorzolamide timololSimbrinza
  • Easier to use with two medications in one drop.
  • May add another medication when needed..
  • May be more effective than using only one medication.
  • Simbrinza may be more effective because it contains two medications
  • It is easier to take two medications in one drop.
Downsides and risks
dorzolamide timololSimbrinza
  • May cause carbonated beverages to taste metallic.
  • You must wait 5 minutes before using another eye drop.
  • Not used in children under 2 years of age.
  • dorzolamide/timolol is not used if you have lung disease or heart conditions relating to a low heart rate or low blood pressure.
  • May cause blurred vision.
  • Simbrinza may cause carbonated beverages to taste metallic..
  • You must wait 5 minutes before using another eye drop
  • Remove contact lenses and leave out for 15 minutes after using the the eyedrop
  • Not used in children under 2 years of age
Tips from our pharmacists for people taking the medication
dorzolamide timololSimbrinza
  • Wash hands before putting drops in eyes.
  • Do not touch the dropper tip to your eye or hands.
  • If you wear contacts remove them and wait 15 minutes, after putting the drop in eye, to replace them.
  • After instilling drops in the eye, press one finger to the inner corner of eye, by the nose, and press lightly for 1 minute.
  • Wash hands before putting drops in eyes.
  • Do not touch the dropper tip to your eye or hands.
  • If you wear contacts remove them and wait 15 minutes, after putting the drop in eye, to replace them.
  • After instilling drops in the eye, press one finger to the inner corner of eye, by the nose, and press lightly for 1 minute.
Learn more
More about dorzolamide timololSide effectsAlternativesFDA package insert
More about SimbrinzaSide effectsReviews & ratingsAlternativesFDA package insert