Compare Dostinex vs. Duopa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dostinex
(Cabergoline)

Duopa
(carbidopa / levodopa)

Coming soon.Treats advanced stages of Parkinson's disease. Duopa (carbidopa / levodopa) pumps carbidopa/levodopa into your body throughout the day. It is reserved for advanced Parkinson's disease when your symptoms become more frequent than the dosing of your tablets.
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Reviews & ratings
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Have you used Dostinex (Cabergoline)?
Worth itNot sureNot worth it

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Have you used Duopa (carbidopa / levodopa)?
Worth itNot sureNot worth it
Side effects
DostinexDuopa

We haven’t found good data for Dostinex side effects.

FDA side effect reports for Dostinex »
  • Problems with j-tube 56%
  • Nausea 30%
  • Constipation 22%
  • Redness and swelling at the j-tube site 19%
  • Difficulty controlling movements 14%
  • Low mood disorder 11%
  • Discharge at the j-tube site 11%
  • Swelling in the arms and legs 8%
  • High blood pressure 8%
  • Flu and cold 8%
More Duopa side effects »
How it works
DostinexDuopa
Coming soon.Duopa (carbidopa / levodopa) is a combination of carbidopa and levodopa. Carbidopa allows levodopa to enter the brain and relieve symptoms of Parkinson's disease.
Type of medication
DostinexDuopa
Prescription only
Available as
DostinexDuopa
  • Pill
  • Liquid
Used for
DostinexDuopa
  • Hyperprolactinemia
Risk factors for serious side effects
DostinexDuopa
Coming soon.
  • Surgery to place the J-tube
  • Taking other medicines for Parkinson's
  • Stopping Duopa (carbidopa / levodopa) suddenly
    • Taking other medicines for Parkinson's disease
    Detailed Duopa (carbidopa / levodopa) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Pain
    DostinexDuopa
    No pain related info.
    • Call your doctor right away if you start having stomach pains around where the pump is connected.
    Sleep
    DostinexDuopa
    No sleep related info.
    • Duopa (carbidopa / levodopa) can make you very sleepy. Don't drive or do anything requiring concentration until you know how it affects you.
    • Duopa (carbidopa / levodopa) can make you very sleepy. Don't drive or do anything that requires your full concentration until you know how Duopa (carbidopa / levodopa) affects you. You're more at risk if you're taking other medicines for Parkinson's. Talk to your doctor if this bothers you.
    Upsides and benefits
    DostinexDuopa
    Coming soon
    • Duopa (carbidopa / levodopa) allows you to have better control of your symptoms than oral tablets, especially in later stages of Parkinson's disease.
    Downsides and risks
    DostinexDuopa
    Coming soon
    • Given via pump so you'll need to have a procedure to attach the pump to your body.
    • You'll need to take good care of the pump so that it doesn't get disconnected or infected.
    • Duopa (carbidopa / levodopa) only lasts for 16 hours. You may need to take an extra dose of carbidopa/levodopa as tablet for nighttime control.
    • You need to keep Duopa (carbidopa / levodopa) in a fridge, but it should sit at room temperature 20 minutes before infusion.
    Tips from our pharmacists for people taking the medication
    DostinexDuopa
    Coming soon
    • Duopa (carbidopa / levodopa) is given via pump. You need to have a minor procedure to connect the pump to your body.
    • You may still need to take carbidopa/levodopa in tablet form at night or if the pump disconnects.
    • Call your doctor right away if you start having stomach pains around where the pump is connected.
    • Duopa (carbidopa / levodopa) is only good for 16 hours. Throw out the cassette when the infusion is done even if there's still medicine left inside.
    • Duopa (carbidopa / levodopa) can make you very sleepy. Don't drive or do anything requiring concentration until you know how it affects you.
    • Don't stop taking Duopa (carbidopa / levodopa) suddenly. It can be very dangerous. Talk to your doctor if you want to stop taking Duopa (carbidopa / levodopa).
    Learn more
    More about DostinexSide effectsReviews & ratingsFDA package insert
    Have you used Dostinex (Cabergoline)?
    Worth itNot sureNot worth it
    More about DuopaSide effectsAlternativesFDA package insert
    Have you used Duopa (carbidopa / levodopa)?
    Worth itNot sureNot worth it