Compare Dostinex vs. tolcapone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dostinex
(cabergoline)

Tasmar
(tolcapone)

Coming soon.Treats Parkinson's disease. Taking Tasmar (tolcapone) is the next step to control Parkinson's disease when carbidopa/levodopa don't work as well, however you might be more likely to have liver damage.
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Coupons for Dostinex
Best available price for 8 (0.5mg) tablets of dostinex
Coupons for tolcapone
Best available price for 60 (100mg) tablets of tolcapone
Reviews & ratings
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Have you used Dostinex (cabergoline)?
Worth itNot sureNot worth it

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Have you used Tasmar (tolcapone)?
Worth itNot sureNot worth it
Side effects
Dostinextolcapone

We haven’t found good data for Dostinex side effects.

FDA side effect reports for Dostinex »
  • Difficulty controlling movement 22%
  • Nausea 12%
  • Sleeping problems 6%
  • Excessive dreaming 4%
  • Muscle cramps 2%
  • Loss of appetite 6%
  • Sleepiness 5%
  • Lightheadedness from standing 3%
  • Diarrhea 8%
More tolcapone side effects »
How it works
Dostinextolcapone
Coming soon.Tasmar (tolcapone) is an enzyme inhibitor that stops levodopa from being broken down. It causes higher levodopa in the brain, which relieves the symptoms of Parkinson's disease.
Type of medication
Dostinextolcapone
Prescription only
Available as
Dostinextolcapone
  • Pill
  • Pill
Used for
Dostinextolcapone
  • Hyperprolactinemia
Risk factors for serious side effects
Dostinextolcapone
    Coming soon.
    • Liver damage
    • Taking other medicines for Parkinson's disease
    • Taking antipsychotic medicines
    Detailed Tasmar (tolcapone) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Food
    Dostinextolcapone
    No food related info.
    • Tasmar (tolcapone) can be taken with or without food.
    Upsides and benefits
    Dostinextolcapone
    Coming soon
    • Tasmar (tolcapone) is part of the medicines used as the most common next step to control Parkinson's disease when carbidopa/levodopa doesn't work as well.
    • Tasmar (tolcapone) is available as a generic.
    • Tasmar (tolcapone) can be taken with or without food.
    Downsides and risks
    Dostinextolcapone
    Coming soon
    • When you first start taking Tasmar (tolcapone), your doctor might have to change the dose a lot because of all the side effects.
    • Tasmar (tolcapone) will only slow the disease down; it is not a cure for Parkinson's disease.
    • Unlike Comtan, Tasmar (tolcapone) is more likely to damage your liver, so you might need regular blood tests for the first few months.
    • Tasmar (tolcapone) is not available as a combination pill with carbidopa/levodopa, unlike Comtan.
    • Tasmar (tolcapone) can cause dry mouth and changes in blood pressure. Changes in blood pressure can make you feel faint and more likely to fall.
    Tips from our pharmacists for people taking the medication
    Dostinextolcapone
    Coming soon
    • Tasmar (tolcapone) can make you dizzy if you've been sitting or lying down for a while. Be very careful when getting up.
    • Don't drive or do anything requiring concentration until you know how Tasmar (tolcapone) affects you.
    • Your urine might be colored dark orange or brown while taking Tasmar (tolcapone). This is normal.
    • You have to keep taking carbidopa/levodopa with Tasmar (tolcapone). Tasmar (tolcapone) won't work by itself to control your Parkinson's disease.
    • Talk to your doctor if you want to stop taking Tasmar (tolcapone). Stopping it suddenly can be very dangerous.
    Learn more
    More about DostinexSide effectsReviews & ratingsFDA package insert
    Have you used Dostinex (cabergoline)?
    Worth itNot sureNot worth it
    More about tolcaponeSide effectsAlternativesFDA package insert
    Have you used Tasmar (tolcapone)?
    Worth itNot sureNot worth it