Compare Doxepin vs. desipramine
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Zonalon (Doxepin) works well treating itchy skin, but could make you sleepy.
Norpramin (desipramine) is not a first choice for treating depression because of its effects on the heart, but it can be good if other medicines haven't worked.
- In clinical trials, Zonalon (Doxepin) was found to be the most effective cream for treating itchy skin.
- You can use Zonalon (Doxepin) for up to 8 days at a time.
- Norpramin (desipramine) is available in generic and in many different strengths, so the dose can be more customized.
- Norpramin (desipramine) has fewer side effects than similar tricyclic antidepressants.
- You need a prescription for Zonalon (Doxepin).
- It isn't available as a generic, so it could be kind of pricey.
- Zonalon (Doxepin) can make you sleepy.
- Zonalon (Doxepin) can interact with other medications, vitamins, or alternative treatments.
- Norpramin (desipramine) isn't recommended if you or your family has heart disease, seizures, or glaucoma.
- Norpramin (desipramine) isn't a first choice for depression because it has more side effects than other antidepressants.
- In some people, Norpramin (desipramine) can make you sleepy. In other people, Norpramin (desipramine) can keep you awake.
- If you have diabetes, Norpramin (desipramine) can make your blood sugar go up.
- Not recommended in children under 12 years of age.
- Skin intching (moderate)
- Cream, gel, or ointment
- Higher risk of suicide
People under age 24
- Serotonin syndrome
...and 5 more risk factors
- Changes to the heartbeat
History of heart disease
- Higher risk for seizures
History of seizures
...and 1 more risk factors