Compare doxycycline vs. Augmentin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Vibramycin (doxycycline)

Prescription only
Treats bacterial infections.

Vibramycin (doxycycline) is good for treating many bacterial infections, but can increase your skin's sensitivity to sunlight and make you more likely to get a sunburn or rash.

4.3/ 7 average rating with 112 reviewsfordoxycycline
Treats bacterial infections.

Augmentin (amoxicillin / clavulanate) is first-choice antibiotic for most common types of infections. However, it may not work against more serious or uncommon types of infections.

5.3/ 7 average rating with 1034 reviewsforAugmentin
Upsides
  • Vibramycin (doxycycline) is a good alternative for some types of bacterial infections for people who are allergic to penicillin.
  • Available in generic.
  • Available as a liquid for those who have trouble swallowing.
  • Vibramycin (doxycycline) is safe for people age 65 or older and those who have kidney problems.
  • Available as generic product.
  • Available in tablet, capsule, and liquid forms.
  • Used to treat most common types of bacterial infections.
  • Side effects are generally not too bad compared to other antibiotics.
Downsides
  • Vibramycin (doxycycline) makes your skin more sensitive to the sun.
  • Vibramycin (doxycycline) can make some birth control less effective, so you may have to use barrier methods (like condoms) while on it.
  • Vitamins, iron supplements, or antacids can't be taken at the same time as Vibramycin (doxycycline).
  • Vibramycin (doxycycline) can cause severe diarrhea that is usually watery and bloody, as late as up to 2 months after finishing the medicine.
  • Many bacteria have developed resistance to this antibiotic.
  • Can cause diarrhea, nausea, and vomiting.
  • Birth control pills may not work as well to prevent pregnancy when taking this medication.
Used for
Dosage forms
  • Pill
  • Delayed release pill
  • Liquid
  • Pill
  • Chewable tablet
  • Extended release
  • Liquid
Price
Lowest price near you
$36.81
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Lowest price near you
$300.98
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Reviews
112 
49%
think this treatment is worth it
36%
think this treatment works well
24%
think this treatment is a hassle

Have you used Vibramycin (doxycycline)?

Leave a review
1034 
68%
think this treatment is worth it
52%
think this treatment works well
13%
think this treatment is a hassle

Have you used Augmentin (amoxicillin / clavulanate)?

Leave a review
Side effects
The Vibramycin (doxycycline) FDA package insert doesn’t have numbers about how common side effects are.
3possible side effects
  • Diarrhea
    15%
  • Vaginal yeast infection
    3%
  • Nausea
    2%
See more detailed side effects
Risks and warnings
  • Color changes in teeth of young children and unborn babies

    Age 8 or younger

    ...and 2 more risk factors

  • Severe diarrhea

    Using Vibramycin (doxycycline) for a long period of time

  • Sunburn or rash

    Being in the sun for a long period of time

    ...and 1 more risk factors

  • Harm to fetus (unborn baby)

    Women who can potentially or want to become pregnant

    ...and 1 more risk factors

See more detailed risks and warnings
  • Serious allergic reaction

    History of penicillin allergy

    ...and 1 more risk factors

  • Liver damage

    Existing liver problems

    ...and 1 more risk factors

  • Superinfection

    Taking Augmentin (amoxicillin / clavulanate) for a long time

    ...and 2 more risk factors

  • Rash

    Mononucleosis

See more detailed risks and warnings