Compare Doxycycline vs. Epiduo

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Vibramycin
(Doxycycline)

Epiduo
(Adapalene / Benzoyl Peroxide)

Treats bacterial infections. Vibramycin (Doxycycline) is good for treating many bacterial infections. It is also available as generic. However, it can make birth control pills less effective. You also have to protect yourself against sunburn.Coming soon.
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Reviews & ratings
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Button Group. All currently active
4.223300970873787Doxycycline
Reviews for Vibramycin (Doxycycline)
50%
of people say Vibramycin (Doxycycline) is worth it
34%
say it works well
23%
say it's a big hassle

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Side effects
DoxycyclineEpiduo

The Doxycycline FDA package insert doesn’t have numbers about how common side effects are.

More about Doxycycline side effects »

We haven’t found good data for Epiduo side effects.

FDA side effect reports for Epiduo »
How it works
DoxycyclineEpiduo
Vibramycin (Doxycycline) is a tetracycline antibiotic. It stops bacteria by preventing them from reproducing and repairing themselves.Coming soon.
Type of medication
DoxycyclineEpiduo
Antibiotic
Tetracycline
Prescription only
Coming soon.
Available as
DoxycyclineEpiduo
  • Pill
  • Delayed release capsule
  • Liquid
  • Cream, gel, or ointment
Used for (click to learn more)
DoxycyclineEpiduo
  • Acne vulgaris
Risk factors for serious side effects
DoxycyclineEpiduo
  • Age 8 years or younger
  • Using oral birth control pills
  • Long antibiotic treatment period
      • Women of childbearing age
      • Women of childbearing age
      • Overweight or obese
      • Taking isotretinoin (Accutane)
      Detailed Vibramycin (Doxycycline) risks & warnings »
      Coming soon.
      Pregnancy category
      DoxycyclineEpiduo
      DFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.No specific alcohol-related info.
      Food
      • Has to be taken with plenty of water and food and you have to stay upright for 30 minutes afterwards to avoid stomach irritation.
      • Take with plenty of food and liquids.
      No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.No specific sex-related info.
      Sleep
      No specific sleep-related info.No specific sleep-related info.
      Weight
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      DoxycyclineEpiduo
      • Available in generic.
      • Available in different forms: tablet, capsule, and suspension.
      • Used to treat many types of bacterial infections.
      • Less resistance seen in bacteria to this antibiotic. Your doctor may run tests to see which antibiotics will kill the bacteria causing your infection.
      Coming soon.
      Downsides and risks
      DoxycyclineEpiduo
      • Can't be used in pregnant women and children under 8 years old.
      • Makes your skin more sensitive to the sun.
      • Has to be taken with plenty of water and food and you have to stay upright for 30 minutes afterwards to avoid stomach irritation.
      • Can make birth control less effective.
      • Can cause diarrhea.
      Coming soon.
      Tips from our pharmacists for people taking the medication
      DoxycyclineEpiduo
      • Take the medication exactly how your doctor tells you to.
      • If you're using birth control pills, this medication can make them less effective.
      • Wear sunblock if you have to go out into the sun since your skin can become more sensitive to sunburn.
      • Can cause diarrhea, nausea or vomiting.
      • Space out any vitamins by at least two hours.
      • Take with plenty of food and liquids.
      • Don't take any medications with bismuth (Pepto-Bismol, Kaopectate) while taking this medication.
      • Don't lie down for at least 30 minutes after taking this medication.
      Coming soon.
      Learn more
      More about DoxycyclineSide effectsReviews & ratingsAlternativesFDA package insert
      More about EpiduoSide effectsReviews & ratingsFDA package insert