Compare Duetact vs. Actos

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Duetact
(pioglitazone / glimepiride)

Actos
(pioglitazone)

Coming soon.Lowers blood sugar. Actos (Pioglitazone) is a last-choice blood sugar-lowering medicine since it's only moderately effective but has a lot of undesirable side effects.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Duetact
Best available price for 30 (30mg/2mg) tablets of pioglitazone-glimepiride
Coupons for Actos
Best available price for 30 (30mg) tablets of actos
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Duetact (pioglitazone / glimepiride)?
Worth itNot sureNot worth it
Reviews for Actos
42%
-42% worse vs. Duetact
30%
-30% worse vs. Duetact
21%
+21% better vs. Duetact
175 reviews
Have you used Actos (pioglitazone)?
Worth itNot sureNot worth it
Side effects
DuetactActos

We haven’t found good data for Duetact side effects.

FDA side effect reports for Duetact »
  • Swelling due to excess fluid 11%
  • Low blood sugar 8%
  • Ear, nose, or throat infection 4%
  • Headache 2%
  • Cardiac failure 2%
  • Back pain 1%
  • Sinus inflammation 1%
  • Muscle pain 2%
More Actos side effects »
How it works
DuetactActos
Coming soon.Actos (Pioglitazone) is an anti-diabetic drug. It improves your body's ability to use insulin to lower your blood sugar.
Type of medication
DuetactActos
Prescription only
Available as
DuetactActos
  • Pill
  • Pill
Used for
DuetactActos
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
DuetactActos
    Coming soon.
    • Heart failure diagnosis
    • Current liver problems
    • Female
    Detailed Actos (pioglitazone) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Weight
    DuetactActos
    No weight related info.
    • Can cause weight gain, headache, and fluid retention.
    • More likely to cause weight gain (2 to 6 pounds or more) compared to other blood sugar-lowering medicines.
    Upsides and benefits
    DuetactActos
    Coming soon
    • Oral blood sugar-lowering medicine.
    • Lowers A1c levels by around 1%. (Hemoglobin A1c measures your average blood sugar over time.)
    • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
    • Rarely causes low blood sugar.
    Downsides and risks
    DuetactActos
    Coming soon
    • May take several weeks to lower blood sugar.
    • You have to check your blood sugar regularly with this medicine.
    • Has more side effects than similar medicines, so it's usually not the first choice for new Type 2 diabetes patients.
    • More likely to cause weight gain (2 to 6 pounds or more) compared to other blood sugar-lowering medicines.
    • Up to 1 in 10 people might get fluid retention (edema), ranging from mild ankle swelling to severe swelling in the lungs that makes it hard to breathe. People with severe congestive heart failure shouldn't use Actos.
    • Raises the risk of bone fractures, especially for people who already have a risk for fractures.
    • Slightly raises the risk of bladder cancer.
    Tips from our pharmacists for people taking the medication
    DuetactActos
    Coming soon
    • Takes several weeks to see full effect on blood sugar control.
    • Can cause weight gain, headache, and fluid retention.
    • Tell your doctor about any mental confusion, persistent abdominal pain, dark urine, yellowing of eyes/skin, or easy bruising.
    • Not recommended for patients with certain heart problems.
    • Check your blood sugar regularly.
    Learn more
    More about DuetactSide effectsFDA package insert
    Have you used Duetact (pioglitazone / glimepiride)?
    Worth itNot sureNot worth it
    More about ActosSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Actos (pioglitazone)?
    Worth itNot sureNot worth it