Compare Duetact vs. Actos
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Duetact (pioglitazone / glimepiride) combines 2 different anti-diabetic medicines into one to help improve blood sugar control, but it is associated with serious complications such as heart failure.
Actos (pioglitazone) can improve blood sugar control but is not a top choice since it has a lot of side effects.
- Taken only once a day.
- Effectively lowers A1c levels and greatly improves blood sugar control as a combination medicine compared to taking the 2 individual medicines alone.
- Duetact (pioglitazone / glimepiride) is a good add-on treatment option for people who are unable to fully control their blood sugar levels through diet and exercise alone.
- Duetact (pioglitazone / glimepiride) is an oral medicine so it might be a good alternative for those who don't like injections.
- Improves sugar control and lowers A1c levels by around 1%.
- Easily taken by mouth as a once a day pill.
- Prevents the harmful effects of high sugar levels on your organs.
- Rarely causes low blood sugar.
- Lower the risk of heart attack or stroke.
- Duetact (pioglitazone / glimepiride) might cause weight gain.
- Might not be a good treatment option for people with heart failure or liver problems.
- Might cause bone fractures, especially for women.
- Relatively expensive as a combination medicine compared to the 2 individual medicines alone.
- Not recommended for people age 65 or older and those with kidney problems because they are more likely to experience side effects such as low blood sugar.
- May take several weeks to lower blood sugar.
- Can cause weight gain.
- People with heart failure or history of bladder cancer shouldn't use this medicine.
- Some people might get fluid accumulation (edema), from minor ankle swelling to fluid in lungs that makes it hard to breathe.
- Raises the risk of bone fractures, especially for people who already have a risk for fractures.
- Low blood sugar27%
- Colds and flu13%
- Heart failure8%
- Sinus infection6%
- Back pain6%
- Pain in arms and legs6%
- Muscle pain5%
- Sore throat5%
- Fluid retention and heart failure
Those with a history of heart failure
- Low blood sugar
Skipping meals or having inconsistent meal times
...and 4 more risk factors
- Bone fractures
- Effect on liver function
Those with a history of liver problems
- Bladder cancer
Those with active bladder cancer or a history of it
- Heart failure
- Liver damage
Current liver problems
- Bladder cancer
History of bladder cancer
- Bone fracture