Compare Effexor vs. Buspar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Effexor (venlafaxine)

Prescription only

Buspar (Buspirone)

Prescription only
Improves mood and helps you relax.

Effexor (venlafaxine) is good for treating depression and anxiety, but it can cause more withdrawal symptoms if you stop suddenly compared to other antidepressants.

3.7/ 5 average rating with 577 reviewsforEffexor
Helps you relax.

Buspar (Buspirone) is effective for treating Generalized Anxiety Disorder (GAD), and less effective for short-term use.

3.4/ 5 average rating with 67 reviewsforBuspar
Upsides
  • Effexor (venlafaxine) effectively treats depression, anxiety, and panic disorder.
  • Effexor (venlafaxine) causes more sleepiness than other antidepressants, so it's beneficial for people who have trouble sleeping.
  • Effexor (venlafaxine) might work when other antidepressants haven't worked since it affects two chemicals in the brain that impact your mood.
  • Effexor (venlafaxine) has several uses, which may be good for people with multiple conditions.
  • Effexor (venlafaxine) is available in generic, which is cheaper.
  • Buspar (Buspirone) works very well to control the symptoms of generalized anxiety syndrome (GAD).
  • Buspar (Buspirone) doesn't cause physical dependence or withdrawal symptoms.
  • Buspar (Buspirone) is only available as a generic, so the price can be pretty cheap.
Downsides
  • Effexor (venlafaxine) can cause side effects such as decreased libido and increased blood pressure.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people aged 24 years or younger.
  • Compared to other antidepressants, it's more likely to cause unpleasant withdrawal symptoms if you suddenly stop taking it and can causes more sleepiness.
  • Buspar (Buspirone) can take as long as four weeks to become fully effective.
  • Not as effective for short-term anxiety conditions or panic disorders.
  • Most people find that it loses effectiveness over long periods of time.
  • Can cause drowsiness or dizziness when you start taking Buspar (Buspirone). Be extremely careful of activities that require mental alertness, such as driving.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
Price
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Reviews
577 reviews so far
62%
saidit'sworth it
51%
saiditworked well
23%
saidit'sa big hassle

Have you used Effexor (venlafaxine)?

Leave a review
67 reviews so far
46%
saidit'sworth it
45%
saiditworked well
22%
saidit'sa big hassle

Have you used Buspar (Buspirone)?

Leave a review
Side effects
39possible side effects
  • Nausea
    37%
  • Headache
    25%
  • Drowsiness
    23%
  • Dry mouth
    22%
  • Dizziness
    19%
  • Difficulty sleeping
    18%
  • Constipation
    15%
  • Nervousness
    13%
  • Weakness
    12%
  • Sweating
    12%
  • Abnormal ejaculation/orgasm
    12%
  • Loss of appetite
    11%
  • Diarrhea
    8%
  • Infection
    6%
  • Vomiting
    6%
  • Anxiety
    6%
  • Blurred vision
    6%
  • Impotence
    6%
  • Indigestion
    5%
  • Tremor
    5%
  • Abnormal dreams
    4%
  • Chills
    3%
  • Rash
    3%
  • Gas
    3%
  • Stiff muscles
    3%
  • Prickling/burning sensation
    3%
  • Yawn
    3%
  • Increased urination
    3%
  • Chest pain
    2%
  • Trauma
    2%
  • Increased blood pressure
    2%
  • Increased heart rate
    2%
  • Decreased libido
    2%
  • Agitation
    2%
  • Confusion
    2%
  • Thinking abnormal
    2%
  • Changes in taste
    2%
  • Ringing in the ears
    2%
  • Dilation of pupils
    2%
See more detailed side effects
21possible side effects
  • Dizziness
    12%
  • Any side effect
    10%
  • Drowsiness
    10%
  • Nausea
    8%
  • Headache
    6%
  • Nervousness
    5%
  • Fatigue
    4%
  • Central nervous system disturbances
    3%
  • Insomnia
    3%
  • Lightheadedness
    3%
  • Dry Mouth
    3%
  • Decreased Concentration
    2%
  • Excitement
    2%
  • Anger/Hostility
    2%
  • Confusion
    2%
  • Depression
    2%
  • Blurred Vision
    2%
  • Abdominal/Gastric Distress
    2%
  • Diarrhea
    2%
  • Numbness
    2%
  • Weakness
    2%
See more detailed side effects
Risks and risk factors
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Serotonin syndrome
    • Taking tricyclic antidepressants, lithium, tramadol, fentanyl, amphetamines, certain headache medications (triptans), St. John's Wort
  • Withdrawal
    • Stopping Effexor (venlafaxine) suddenly
  • Increased bleeding
    • Taking other blood-thinning drugs (including aspirin, NSAIDs such as Advil, warfarin)
  • Increased blood pressure
    • Bipolar disorder
      • History of bipolar disorder
      • At risk for bipolar disorder
    See more detailed risks and warnings
    • Elevated blood pressure
      • Taking with MAOIs
      • Taking with Zyvox or methylene blue
    • Withdrawal reactions
      • Taking with or converting from benzodiazepine medicines
    • Abnormal and involuntary muscle movements
      • Duration of treatment
    See more detailed risks and warnings