Compare Effexor vs. Celexa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Effexor (venlafaxine)

Prescription only

Celexa (citalopram)

Prescription only
Improves mood and helps you relax.

Effexor (venlafaxine) is good for treating depression and anxiety, but it can cause more withdrawal symptoms if you stop suddenly compared to other antidepressants.

5.1/ 7 average rating with 577 reviewsforEffexor
Improves mood.

Celexa (citalopram) is good for treating depression and anxiety. Side effects are less likely to happen compared to other antidepressants; however, it is not the best choice for people with heart or liver problems.

5.0/ 7 average rating with 520 reviewsforCelexa
Upsides
  • Effexor (venlafaxine) effectively treats depression, anxiety, and panic disorder.
  • Effexor (venlafaxine) causes more sleepiness than other antidepressants, so it's beneficial for people who have trouble sleeping.
  • Effexor (venlafaxine) might work when other antidepressants haven't worked since it affects two chemicals in the brain that impact your mood.
  • Effexor (venlafaxine) has several uses, which may be good for people with multiple conditions.
  • Effexor (venlafaxine) is available in generic, which is cheaper.
  • Effectively relieves depression symptoms.
  • This medicine is not as drowsy as other antidepressants.
  • Available as a generic, which is cheaper.
Downsides
  • Effexor (venlafaxine) can cause side effects such as decreased libido and increased blood pressure.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people aged 24 years or younger.
  • Compared to other antidepressants, it's more likely to cause unpleasant withdrawal symptoms if you suddenly stop taking it and can causes more sleepiness.
  • Can cause sexual side effects like decreased sex drive, difficulties with orgasm or ejaculation, and minor weight gain (1 to 5 pounds).
  • Celexa (citalopram) may not be a good option if you have heart or liver problems.
  • Like most antidepressants, Celexa (citalopram) can increase risk of suicidal thoughts and behavior in people younger than 24 years.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Liquid
Price
Lowest price near you
$16.2
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$4
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Reviews
577 
62%
think this treatment is worth it
51%
think this treatment works well
23%
think this treatment is a hassle

Have you used Effexor (venlafaxine)?

Leave a review
520 
61%
think this treatment is worth it
51%
think this treatment works well
16%
think this treatment is a hassle

Have you used Celexa (citalopram)?

Leave a review
Side effects
10possible side effects
  • Nausea
    37%
  • Headache
    25%
  • Drowsiness
    23%
  • Dry mouth
    22%
  • Dizziness
    19%
  • Difficulty sleeping
    18%
  • Constipation
    15%
  • Nervousness
    13%
  • Weakness
    12%
  • Sweating
    12%
See more detailed side effects
The Celexa (citalopram) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Serotonin syndrome

    Taking tricyclic antidepressants, lithium, tramadol, fentanyl, amphetamines, certain headache medications (triptans), St. John's Wort

  • Withdrawal

    Stopping Effexor (venlafaxine) suddenly

  • Increased bleeding

    Taking other blood-thinning drugs (including aspirin, NSAIDs such as Advil, warfarin)

  • Increased blood pressure

  • Bipolar disorder

    History of bipolar disorder

    ...and 1 more risk factors

See more detailed risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Serotonin syndrome

    Taking tricyclic antidepressants, lithium, tramadol, fentanyl, amphetamines, certain headache medications (triptans), St. John's Wort

  • Bipolar disorder

    History of bipolar disorder

    ...and 1 more risk factors

  • Withdrawal

    Stopping Celexa (citalopram) abruptly

  • Lower maximum dose in some people

    Higher dose

    ...and 3 more risk factors

  • Increased bleeding

    Taking other blood-thinning drugs (including aspirin, NSAIDs such as Advil, warfarin)

See more detailed risks and warnings