Compare Effexor vs. Valium

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Effexor (venlafaxine)

Prescription only

Valium (diazepam)

Prescription only
Improves mood and helps you relax.

Effexor (venlafaxine) is good for treating depression and anxiety, but it can cause more withdrawal symptoms if you stop suddenly compared to other antidepressants.

5.1/ 7 average rating with 577 reviewsforEffexor
Helps you relax.

Valium (diazepam) is effective for occasional or short-term use for anxiety and muscle spasm. Compared to similar drugs, Valium (diazepam) acts very quickly but can have interactions with other medicines.

5.2/ 7 average rating with 976 reviewsforValium
Upsides
  • Effexor (venlafaxine) effectively treats depression, anxiety, and panic disorder.
  • Effexor (venlafaxine) causes more sleepiness than other antidepressants, so it's beneficial for people who have trouble sleeping.
  • Effexor (venlafaxine) might work when other antidepressants haven't worked since it affects two chemicals in the brain that impact your mood.
  • Effexor (venlafaxine) has several uses, which may be good for people with multiple conditions.
  • Effexor (venlafaxine) is available in generic, which is cheaper.
  • Valium (diazepam) effectively relieves anxiety and muscle spasms.
  • Valium (diazepam) has less severe withdrawal symptoms compared to other similar drugs.
  • Works very quickly.
  • Available in generic.
Downsides
  • Effexor (venlafaxine) can cause side effects such as decreased libido and increased blood pressure.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people aged 24 years or younger.
  • Compared to other antidepressants, it's more likely to cause unpleasant withdrawal symptoms if you suddenly stop taking it and can causes more sleepiness.
  • Use of Valium (diazepam) can cause memory problems, drowsiness, dizziness, and confusion.
  • Valium (diazepam) can be habit-forming, so it's not typically used for long-term treatment.
  • Most people find that their body will get used to Valium (diazepam) levels and they may need higher doses over time to achieve the same effect.
  • People with severe liver problems should not take Valium (diazepam). Several drugs can also interfere with how Valium (diazepam) works.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Liquid
Price
Lowest price near you
$16.2
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Lowest price near you
$6.58
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Reviews
577 
62%
think this treatment is worth it
51%
think this treatment works well
23%
think this treatment is a hassle

Have you used Effexor (venlafaxine)?

Leave a review
976 
70%
think this treatment is worth it
53%
think this treatment works well
15%
think this treatment is a hassle

Have you used Valium (diazepam)?

Leave a review
Side effects
10possible side effects
  • Nausea
    37%
  • Headache
    25%
  • Drowsiness
    23%
  • Dry mouth
    22%
  • Dizziness
    19%
  • Difficulty sleeping
    18%
  • Constipation
    15%
  • Nervousness
    13%
  • Weakness
    12%
  • Sweating
    12%
See more detailed side effects
The Valium (diazepam) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Serotonin syndrome

    Taking tricyclic antidepressants, lithium, tramadol, fentanyl, amphetamines, certain headache medications (triptans), St. John's Wort

  • Withdrawal

    Stopping Effexor (venlafaxine) suddenly

  • Increased bleeding

    Taking other blood-thinning drugs (including aspirin, NSAIDs such as Advil, warfarin)

  • Increased blood pressure

  • Bipolar disorder

    History of bipolar disorder

    ...and 1 more risk factors

See more detailed risks and warnings
  • Decreased breathing from use with opioids

    Taking Valium (diazepam) with opioids, drugs or alcohol

    ...and 1 more risk factors

  • Dependence and withdrawal

    History of substance abuse

    ...and 4 more risk factors

  • Driving impairment

    Alcohol use with Valium (diazepam)

    ...and 1 more risk factors

  • Drug interactions

    Current liver problems

    ...and 1 more risk factors

See more detailed risks and warnings