Compare Effexor vs. Zomig

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Coming soon.

Effexor
(Venlafaxine)

Zomig
(Zolmitriptan)

Improves mood and helps you relax. Effexor (Venlafaxine) is good for treating depression and anxiety. May work when other antidepressants haven't, it's but more likely to cause side effects and withdrawal symptoms than other antidepressants.Coming soon.
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Reviews & ratings
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5.07Effexor
Reviews for Effexor (Venlafaxine)
62%
of people (All ages) say Effexor (Venlafaxine) is worth it
51%
say it works well
23%
say it's a big hassle
577 reviews
Have you used Effexor (Venlafaxine)?
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Have you used Zomig (Zolmitriptan)?
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Side effects
EffexorZomig
  • Nausea 42%
  • Drowsiness 22%
  • Dizziness 20%
  • Nervousness 17%
  • Loss of appetite 15%
  • Sweating 14%
  • Muscle weakness 14%
  • Sleep difficulty 13%
  • Anxiety 7%
  • Vomiting 7%
More Effexor side effects »

We haven’t found good data for Zomig side effects.

FDA side effect reports for Zomig »
How it works
EffexorZomig
Effexor (Venlafaxine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. It increases serotonin and norepinephrine activity in the brain, which regulate mood.Coming soon.
Type of medication
EffexorZomig
Antidepressant
Serotonin-norepinephrine reuptake inhibitor (SNRI)
Prescription only
Coming soon.
Available as
EffexorZomig
  • Pill
  • Extended release
  • Pill
  • Dissolving tablet
  • Nasal spray
Used for (click to learn more)
EffexorZomig
  • Migraine (Acute)
Risk factors for serious side effects
EffexorZomig
  • Age 24 years or younger
  • Using other medications that affect serotonin
  • Stopping Effexor (Venlafaxine) suddenly
  • History of high blood pressure
  • Taking other blood-thinning drugs
Detailed risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Sex
EffexorZomig
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
No sex related info.
Upsides and benefits
EffexorZomig
  • Effective at relieving depression and anxiety symptoms.
  • Lowers relapse rates of depression.
  • Causes more sleepiness than other antidepressants, so it's good for people who have trouble sleeping.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
  • Might work when other antidepressants haven't worked since it affects two chemicals in the brain that impact your mood. Many other antidepressants affect only serotonin, but not norepinephrine too.
Coming soon
Downsides and risks
EffexorZomig
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
  • Not the best option for people with high blood pressure.
  • Overdosing on this medication could be fatal.
  • It's more likely to cause nausea and vomiting or make you feel sick if you miss a dose than other antidepressants. Also causes more sleepiness than others.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
Coming soon
Tips from our pharmacists for people taking the medication
EffexorZomig
  • Takes about 8 to 12 weeks to see the medication's full effects on your mood.
  • You can take the extended-release form once a day with food either in the morning or in the evening at about the same time each day.
  • Extended-release capsules should be swallowed whole. If you can’t swallow pills, open the capsule, sprinkle it on a spoonful of applesauce and then swallow it without chewing.
  • Stop taking it slowly to avoid getting withdrawal symptoms.
  • Tell your doctor if you notice sudden mood changes or unusual thoughts.
Coming soon
Learn more
More about EffexorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Effexor (Venlafaxine)?
Worth itNot sureNot worth it
More about ZomigSide effectsReviews & ratingsFDA package insert
Have you used Zomig (Zolmitriptan)?
Worth itNot sureNot worth it