Compare Elavil vs. amoxapine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Elavil (amitriptyline)

Prescription only

Asendin (amoxapine)

Prescription only
Improves mood.

Elavil (amitriptyline) regulates mood and treats nerve pain, but has more side effects than alternatives.

3.3/ 5 average rating with 134 reviewsforElavil
Stabilizes your mood.

While Asendin (amoxapine) can treat depression, you have to take it several times a day and it can make you feel sleepy.

Upsides
  • Elavil (amitriptyline) works well to treat nerve pain and is non-habit forming.
  • Asendin (amoxapine) can be used to treat more severe forms of depression.
  • Compared to similar medicines, Asendin (amoxapine) improves the mood in depression more quickly.
  • Asendin (amoxapine) is available as generic.
Downsides
  • Elavil (amitriptyline) has more bothersome side effects than other antidepressants.
  • Asendin (amoxapine) is not a first choice medicine for depression because of side effects.
  • In some people, Asendin (amoxapine) can stop working as early as 2-3 months after you start taking it.
  • Not recommended in older people, children under 16, or people who've had a history of seizures.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
134 reviews so far
53%
saidit'sworth it
36%
saiditworked well
25%
saidit'sa big hassle

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Side effects
The Elavil (amitriptyline) FDA package insert doesn’t have numbers about how common side effects are.
4possible side effects
  • Drowsiness or fatigue
    14%
  • Dry mouth
    14%
  • Constipation
    12%
  • Vision changes
    7%
See more detailed side effects
Risks and risk factors
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Mania
    • History of bipolar disorder
    • At risk for bipolar disorder
  • Heart problems
    • History of cardiovascular disease
  • Dizziness and falls
    • Age 65 years or older
    • Taking medicines to control blood pressure
  • Dehydration
    • Age 65 years or older
See more detailed risks and warnings
  • Increased risk of suicide
    • People under age 24
  • Vision changes
    • Glaucoma
  • Difficulty controlling movements
  • Neuroleptic malignant syndrome
    • Taking antidepressants
  • Slowed breathing
    • Taking opioids for pain relief or medicines for anxiety
  • Anticholinergic effects/Dehydration
    • Over age 65
See more detailed risks and warnings