Compare Elavil vs. Surmontil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Elavil
(amitriptyline)

Surmontil
(trimipramine)

Improves mood and relieves certain kinds of pain. Elavil (Amitriptyline) is an older antidepressant that's sometimes used to treat pain and sleep problems, but it can have more side effects than similar medications.Improves your mood. Surmontil (trimipramine) is good at treating depression, but it can cause more side effects, like sleepiness and weight gain, compared to other medicines.
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Coupons for Elavil
Best available price for 30 (25mg) tablets of amitriptyline
Coupons for Surmontil
Best available price for 30 (100mg) capsules of trimipramine
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.48Elavil
Reviews for Elavil (amitriptyline)
53%
of people (All ages) say Elavil (amitriptyline) is worth it
36%
say it works well
25%
say it's a big hassle
134 reviews
Have you used Elavil (amitriptyline)?
Worth itNot sureNot worth it
Reviews for Surmontil (trimipramine)
Not enough review data. Review it!
-20% worse vs. Elavil (amitriptyline)
Not enough review data. Review it!
-3% worse vs. Elavil (amitriptyline)
Not enough review data. Review it!
+25% better vs. Elavil (amitriptyline)
Have you used Surmontil (trimipramine)?
Worth itNot sureNot worth it
Side effects
ElavilSurmontil

The Elavil FDA package insert doesn’t have numbers about how common side effects are.

More about Elavil side effects »

The Surmontil FDA package insert doesn’t have numbers about how common side effects are.

More about Surmontil side effects »
How it works
ElavilSurmontil
Elavil (Amitriptyline) is a tricyclic antidepressant (TCA). Researchers don't know exactly how it works. It may change serotonin and norepinephrine activity in the brain, which regulates mood and pain perception. It also has sedative effects.Surmontil (trimipramine) is a tricyclic antidepressant. It raises the amount of serotonin and norepinephrine in the brain, 2 chemicals that are known to regulate mood.
Type of medication
ElavilSurmontil
Prescription only
Prescription only
Available as
ElavilSurmontil
  • Pill
  • Pill
Used for
ElavilSurmontil
Risk factors for serious side effects
ElavilSurmontil
  • Age 24 years or younger
  • History of bipolar disorder
  • At risk for bipolar disorder
  • History of cardiovascular disease
  • Age 65 years or older
Detailed Elavil (amitriptyline) risks & warnings »
  • People under age 24
  • Tricyclic antidepressants
  • Fentanyl
  • Tramadol
  • Buspirone
Detailed Surmontil (trimipramine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
ElavilSurmontil
No food related info.
  • Can be taken with or without food.
Pain
ElavilSurmontil
  • Low doses work well to treat certain kinds of chronic pain. It can take 2 weeks to feel the full effects of the medication.
No pain related info.
Sleep
ElavilSurmontil
  • Can cause dizziness, drowsiness, constipation, and weight gain.
No sleep related info.
Weight
ElavilSurmontil
  • It's more likely to cause sleepiness, nausea, constipation, diarrhea, and weight gain (1 to 5 pounds) than other antidepressants.
No weight related info.
Upsides and benefits
ElavilSurmontil
  • Low doses work well to treat certain kinds of chronic pain. It can take 2 weeks to feel the full effects of the medication.
  • Low doses of Elavil (Amitriptyline) start working in 45 minutes to help you sleep better.
  • Six out of every ten people who use an antidepressant for the first time find that it works for them.
  • Surmontil (trimipramine) is part of the first choice medicines to treat depression.
  • Available in generic and in three different strengths.
  • Can be taken once a day, usually before you go to bed.
  • Can be taken with or without food.
Downsides and risks
ElavilSurmontil
  • When used for depression, Elavil (Amitriptyline) causes more side effects and has a higher risk of overdose than other antidepressants. It's usually used when other medications haven't worked.
  • It's more likely to cause sleepiness, nausea, constipation, diarrhea, and weight gain (1 to 5 pounds) than other antidepressants.
  • People age 65 and older have a higher risk for this medication's side effects.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
  • You might not notice changes in your mood until you've taken Surmontil (trimipramine) for several weeks.
  • Stopping Surmontil (trimipramine) suddenly without telling your doctor can be dangerous.
  • Surmontil (trimipramine) can cause more side effects than other medicines used to treat depression.
Tips from our pharmacists for people taking the medication
ElavilSurmontil
  • Take at bedtime to avoid some of its side effects.
  • Can cause dizziness, drowsiness, constipation, and weight gain.
  • Stop taking it slowly to avoid getting withdrawal symptoms.
  • Tell your doctor if you notice sudden mood changes or unusual thoughts.
  • Take Surmontil (trimipramine) at night since it can make you sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
  • If you forget a dose, take it as soon as you remember, unless it's time for your next dose. Don't take extra medicine to make up for the missed dose.
  • Don't stop taking Surmontil (trimipramine) without talking to your doctor first.
  • Be very careful getting up if you've been sitting or lying down for a while since you can feel dizzy.
Learn more
More about ElavilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Elavil (amitriptyline)?
Worth itNot sureNot worth it
More about SurmontilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Surmontil (trimipramine)?
Worth itNot sureNot worth it