Compare Eldepryl vs. carbidopa / levodopa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Eldepryl (selegiline)

Prescription only
Treats Parkinson's disease.

Used with other medicines for Parkinson's disease to boost its effect.

Treats Parkinson's disease.

Sinemet (carbidopa / levodopa) is the first choice treatment for Parkinson's disease.

Upsides
  • There are two different versions of Eldepryl (selegiline), a quick dissolving tablet and a regular tablet.
  • Eldepryl (selegiline) is one of the recommended medicines you can take along with carbidopa/levodopa if your Parkinson's disease is getting worse.
  • Sinemet (carbidopa / levodopa) is widely available as a regular pill, a quick dissolving pill or a liquid taken through a feeding tube.
  • Sinemet (carbidopa / levodopa) is available in generic.
Downsides
  • You may have to limit the amount of cheese, smoked meat, and soy sauce you eat while taking Eldepryl (selegiline) since it can raise your blood pressure.
  • Can keep you up at night if you take it later in the day
  • Doesn't work by itself to treat Parkinson's disease.
  • Can make you very sleepy.
  • Can stain your saliva, sweat and urine a dark color.
  • Will lose its effect over time as your disease progresses.
  • May need to be taken several times during day to control symptoms of Parkinson's disease
  • May cause unusual cravings in some people.
Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Pill
  • Dissolving tablet
Price
Lowest price near you
$25.69
Find instant savings
Lowest price near you
$18.44
Find instant savings
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
Reviews
Not enough review data.Leave a review
Not enough review data.Leave a review
Side effects
10possible side effects
  • Skin irritation at the patch
    24%
  • Headache
    18%
  • Insomnia
    12%
  • Diarrhea
    9%
  • Dry mouth
    8%
  • Weight loss of at least 5%
    5%
  • Indigestion
    4%
  • Rash
    4%
  • Sore throat
    3%
  • Sinus infection
    3%
See more detailed side effects
The Sinemet (carbidopa / levodopa) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Increased blood pressure

    Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats

    ...and 1 more risk factors

  • Serotonin syndrome

    Tricyclic antidepressants

    ...and 5 more risk factors

  • Falling asleep during the day

    Taking other medicines for Parkinson's

See more detailed risks and warnings
  • Falling asleep during the day

    Taking other medicines for Parkinson's

  • High fever and confusion

    Stopping Sinemet (carbidopa / levodopa) suddenly

  • Lack of impulse control

    Taking other medicines for Parkinson's disease

See more detailed risks and warnings