Compare Eldepryl vs. carbidopa / levodopa extended release

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Eldepryl (selegiline)

Prescription only
Treats Parkinson's disease.

Used with other medicines for Parkinson's disease to boost its effect.

Treats Parkinson's disease.

Sinemet CR (carbidopa / levodopa extended release) is the first choice treatment for Parkinson's disease.

Upsides
  • There are two different versions of Eldepryl (selegiline), a quick dissolving tablet and a regular tablet.
  • Eldepryl (selegiline) is one of the recommended medicines you can take along with carbidopa/levodopa if your Parkinson's disease is getting worse.
  • Sinemet CR (carbidopa / levodopa extended release) is released over a long period of time in your body and can allow you to take fewer pills less frequently.
Downsides
  • You may have to limit the amount of cheese, smoked meat, and soy sauce you eat while taking Eldepryl (selegiline) since it can raise your blood pressure.
  • Can keep you up at night if you take it later in the day
  • Doesn't work by itself to treat Parkinson's disease.
  • Sinemet CR (carbidopa / levodopa extended release) can make you very sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
  • Your saliva, sweat and urine may have dark color and stain your clothing while taking Sinemet CR (carbidopa / levodopa extended release).
  • Sinemet CR (carbidopa / levodopa extended release) will lose its effect over time. If you notice it wearing off sooner than you'd like, talk to your doctor.
  • Sinemet CR (carbidopa / levodopa extended release) may cause unusual cravings in some people.
Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Extended release
Price
Lowest price near you
$25.69
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Lowest price near you
$90.2
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Side effects
10possible side effects
  • Skin irritation at the patch
    24%
  • Headache
    18%
  • Insomnia
    12%
  • Diarrhea
    9%
  • Dry mouth
    8%
  • Weight loss of at least 5%
    5%
  • Indigestion
    4%
  • Rash
    4%
  • Sore throat
    3%
  • Sinus infection
    3%
See more detailed side effects
10possible side effects
  • Difficulty controlling movements
    17%
  • Nausea
    6%
  • Hallucinations
    4%
  • Confusion
    4%
  • Dizziness
    3%
  • Depression
    2%
  • Urinary tract infection
    2%
  • Headache
    2%
  • Unusual dreams
    2%
  • Muscle spasms
    2%
See more detailed side effects
Risks and warnings
  • Increased blood pressure

    Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats

    ...and 1 more risk factors

  • Serotonin syndrome

    Tricyclic antidepressants

    ...and 5 more risk factors

  • Falling asleep during the day

    Taking other medicines for Parkinson's

See more detailed risks and warnings
  • Falling asleep during the day

    Taking other medicines for Parkinson's

  • High fever and confusion

    Stopping Sinemet CR (carbidopa / levodopa extended release) suddenly

  • Lack of impulse control

    Taking other medicines for Parkinson's disease

See more detailed risks and warnings