Compare Eldepryl vs. Duopa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Eldepryl
(selegiline)

Duopa
(carbidopa / levodopa)

Treats Parkinson's disease. Used with other medicines for Parkinson's disease to boost its effect.Treats advanced stages of Parkinson's disease. Duopa (carbidopa / levodopa) pumps carbidopa/levodopa into your body throughout the day. It is reserved for advanced Parkinson's disease when your symptoms become more frequent than the dosing of your tablets.
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Coupons for Eldepryl
Best available price for 60 (5mg) tablets of eldepryl
Coupons for Duopa
Best available price for 500 (100ml of 4.63mg/20mg/ml) cartridges of duopa
Reviews & ratings
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Have you used Eldepryl (selegiline)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Duopa (carbidopa / levodopa)?
Worth itNot sureNot worth it
Side effects
EldeprylDuopa
  • Skin irritation at the patch 12%
  • Headache 1%
  • Sleep difficulty 5%
  • Diarrhea 2%
  • Dry mouth 2%
  • Weight loss of at least 5% 2%
  • Indigestion 1%
  • Rash 2%
  • Sinus infection 2%
  • Sore throat 1%
More Eldepryl side effects »
  • Problems with j-tube 56%
  • Nausea 30%
  • Constipation 22%
  • Redness and swelling at the j-tube site 19%
  • Difficulty controlling movements 14%
  • Low mood disorder 11%
  • Discharge at the j-tube site 11%
  • Swelling in the arms and legs 8%
  • High blood pressure 8%
  • Flu and cold 8%
More Duopa side effects »
How it works
EldeprylDuopa
Eldepryl (selegiline) is a selective monoamine oxidase inhibitor. It regulates the amount of dopamine in your body.Duopa (carbidopa / levodopa) is a combination of carbidopa and levodopa. Carbidopa allows levodopa to enter the brain and relieve symptoms of Parkinson's disease.
Type of medication
EldeprylDuopa
Prescription onlyPrescription only
Available as
EldeprylDuopa
  • Pill
  • Dissolving tablet
  • Liquid
Used for
EldeprylDuopa
Risk factors for serious side effects
EldeprylDuopa
  • Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
  • Taking cough and cold medicines like dextromethorphan (Robitussin DM), pseudoephedrine (Sudafed)
  • Tricyclic antidepressants
  • Fentanyl
  • Tramadol
Detailed Eldepryl (selegiline) risks & warnings »
  • Surgery to place the J-tube
  • Taking other medicines for Parkinson's
  • Stopping Duopa (carbidopa / levodopa) suddenly
  • Taking other medicines for Parkinson's disease
Detailed Duopa (carbidopa / levodopa) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
EldeprylDuopa
  • Avoid eating foods high in tyramine while taking Eldepryl (selegiline), since it can increase your blood pressure.
No food related info.
Pain
EldeprylDuopa
No pain related info.
  • Call your doctor right away if you start having stomach pains around where the pump is connected.
Sleep
EldeprylDuopa
No sleep related info.
  • Duopa (carbidopa / levodopa) can make you very sleepy. Don't drive or do anything that requires your full concentration until you know how Duopa (carbidopa / levodopa) affects you. You're more at risk if you're taking other medicines for Parkinson's. Talk to your doctor if this bothers you.
  • Duopa (carbidopa / levodopa) can make you very sleepy. Don't drive or do anything requiring concentration until you know how it affects you.
Upsides and benefits
EldeprylDuopa
  • There are two different versions of Eldepryl (selegiline), a quick dissolving tablet and a regular tablet.
  • Eldepryl (selegiline) is one of the recommended medicines you can take along with carbidopa/levodopa if your Parkinson's disease is getting worse.
  • Duopa (carbidopa / levodopa) allows you to have better control of your symptoms than oral tablets, especially in later stages of Parkinson's disease.
Downsides and risks
EldeprylDuopa
  • You may have to limit the amount of cheese, smoked meat, and soy sauce you eat while taking Eldepryl (selegiline) since it can raise your blood pressure.
  • Can keep you up at night if you take it later in the day
  • Doesn't work by itself to treat Parkinson's disease.
  • Given via pump so you'll need to have a procedure to attach the pump to your body.
  • You'll need to take good care of the pump so that it doesn't get disconnected or infected.
  • Duopa (carbidopa / levodopa) only lasts for 16 hours. You may need to take an extra dose of carbidopa/levodopa as tablet for nighttime control.
  • You need to keep Duopa (carbidopa / levodopa) in a fridge, but it should sit at room temperature 20 minutes before infusion.
Tips from our pharmacists for people taking the medication
EldeprylDuopa
  • Watch how much smoked meat, cheese, pickles and soy sauce you eat while taking Eldepryl (selegiline) since it can raise your blood pressure.
  • Avoid taking your doses later in the day because it can keep you up.
  • Don't stop Eldepryl (selegiline) suddenly without talking to your doctor, since it can be dangerous.
  • Duopa (carbidopa / levodopa) is given via pump. You need to have a minor procedure to connect the pump to your body.
  • You may still need to take carbidopa/levodopa in tablet form at night or if the pump disconnects.
  • Call your doctor right away if you start having stomach pains around where the pump is connected.
  • Duopa (carbidopa / levodopa) is only good for 16 hours. Throw out the cassette when the infusion is done even if there's still medicine left inside.
  • Duopa (carbidopa / levodopa) can make you very sleepy. Don't drive or do anything requiring concentration until you know how it affects you.
  • Don't stop taking Duopa (carbidopa / levodopa) suddenly. It can be very dangerous. Talk to your doctor if you want to stop taking Duopa (carbidopa / levodopa).
Learn more
More about EldeprylSide effectsAlternativesFDA package insert
Have you used Eldepryl (selegiline)?
Worth itNot sureNot worth it
More about DuopaSide effectsAlternativesFDA package insert
Have you used Duopa (carbidopa / levodopa)?
Worth itNot sureNot worth it