Compare Eliquis vs. Heparin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Eliquis
(Apixaban)

Heparin

Prevents blood clots. Eliquis (Apixaban) is an easy to use and effective way to prevent blood clots from forming in your veins.Prevents blood clots. Heparin is a good anticoagulant that prevents blood clots. However, you'll need to get frequent blood tests to make sure it's working well.
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Reviews & ratings
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Have you used Eliquis (Apixaban)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Heparin?
Worth itNot sureNot worth it
Side effects
EliquisHeparin
  • All bleeding 6%
  • Nosebleed 3%
  • Nonmajor bleeding 2%
  • Collection of blood 1%
More Eliquis side effects »

We haven’t found good data for Heparin side effects.

FDA side effect reports for Heparin »
How it works
EliquisHeparin
Eliquis (Apixaban) is a factor Xa inhibitor anticoagulant and prevents the formation of blood clots in your veins.Heparin is an anticoagulant that binds with proteins and platelets to stop blood clots from being made and traveling to the brain, heart, and lungs.
Type of medication
EliquisHeparin
Anticoagulant
Factor Xa inhibitor
Prescription only
Anticoagulant
Heparin
Prescription only
Available as
EliquisHeparin
  • Pill
  • Injection
Used for (click to learn more)
EliquisHeparin
Risk factors for serious side effects
EliquisHeparin
  • Stopping Eliquis (Apixaban) early
  • Spinal puncture (spinal tap)
  • Getting anesthesia in the spine (epidural anesthesia)
  • History of bleeding problems
  • Severe high blood pressure
  • Older age
  • Artificial heart valve
  • Current kidney problems
  • Current liver problems
Detailed Eliquis (Apixaban) risks & warnings »
  • History of bleeding problems
  • Severe high blood pressure
  • Older age
  • Heparin-induced thrombocytopenia
Detailed Heparin risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
EliquisHeparin
  • Take twice a day, with or without food, at the same time each day.
No food related info.
Kidneys and liver
EliquisHeparin
  • Eliquis (Apixaban) is processed by the kidney and liver. If you have kidney or liver problems, talk to your doctor about possibly switching to a different medicine to prevent increased risk for side effects.
No kidneys and liver related info.
Upsides and benefits
EliquisHeparin
  • Eliquis (Apixaban) is very effective in reducing the threat of stroke in people with Afib or other clotting disorders.
  • Eliquis (Apixaban) doesn't require regular blood testing and doesn't have dietary restrictions.
  • If you've had clots in your legs or lungs before, Eliquis (Apixaban) can lower the risk of these forming again.
  • Safe to use in pregnancy and if you're breast feeding.
  • There are other medications that can help stop unexpected bleeding while taking Heparin.
  • Available as a generic medication.
  • Usually used in the hospital, but can be given at home too.
Downsides and risks
EliquisHeparin
  • You can bruise easier and if you cut yourself, it'll take longer to stop the bleeding. Always look for signs of internal bleeding, such as dark urine or blood in your stool.
  • Can't be used if you have artificial heart valves.
  • Never stop taking Eliquis (Apixaban) without talking to your doctor first.
  • Eliquis (Apixaban) isn't available as a generic, so it can be pricey.
  • You'll need to get labs/blood draws done on a regular basis to make sure the drug is working and to make sure you don't get unexpected side effects.
  • You can be at higher risk for bleeding or clotting while taking Heparin compared to other anticoagulants.
Tips from our pharmacists for people taking the medication
EliquisHeparin
  • Take twice a day, with or without food, at the same time each day.
  • Needs to be stopped prior to dental procedures or surgery.
  • You can bruise easier and if you have a cut, it can take longer for bleeding to stop.
  • Do not take with other drugs that affect your blood, like aspirin, ibuprofen, warfarin, or SSRIs.
  • Call a doctor immediately if you have dizziness, weakness, or a really bad headache.
  • Make sure to change where you inject Heparin every time.
  • Don't take aspirin or other anti-inflammatory medications without talking to your doctor first.
  • You will have to do regular blood draws or labs to make sure that Heparin is working for you.
Learn more
More about EliquisSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Eliquis (Apixaban)?
Worth itNot sureNot worth it
More about HeparinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Heparin?
Worth itNot sureNot worth it