Compare Eliquis vs. Heparin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Eliquis
(apixaban)

heparin

Prevents blood clots. Eliquis (apixaban) is an effective way to prevent blood clots from forming in your veins, but you have to take it twice a day, and your doctor might have to change the dose a lot.Prevents blood clots. Heparin is a good anticoagulant that prevents blood clots. However, you'll need to get frequent blood tests to make sure it's working well.
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Best available price for 60 (5mg) tablets of eliquis
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.26Eliquis
Reviews for Eliquis
47%
of people (All ages) say Eliquis is worth it
58%
say it works well
21%
say it's a big hassle
Have you used Eliquis (apixaban)?
Worth itNot sureNot worth it

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Have you used Heparin?
Worth itNot sureNot worth it
Side effects
EliquisHeparin
  • Major bleed 2%
  • Bleeding 12%
  • Nausea 3%
  • Low red blood cells 3%
  • All bleeding 15%
  • Nose bleeding 3%
  • Severe bruising 2%
  • Blood in the urine 2%
  • Nosebleeds 3%
  • Blood clots 1%
More Eliquis side effects »

We haven’t found good data for Heparin side effects.

FDA side effect reports for Heparin »
How it works
EliquisHeparin
Eliquis (apixaban) is a factor Xa inhibitor anticoagulant that stops the formation of blood clots in your body so you're less likely to have a stroke or heart attack.Heparin is an anticoagulant that binds with proteins and platelets to stop blood clots from being made and traveling to the brain, heart, and lungs.
Type of medication
EliquisHeparin
Prescription onlyPrescription only
Available as
EliquisHeparin
  • Pill
  • Injection
Used for
EliquisHeparin
Risk factors for serious side effects
EliquisHeparin
  • Stopping Eliquis (apixaban) prematurely
  • Spinal puncture (spinal tap)
  • Getting anesthesia in the spine (epidural anesthesia)
  • History of spinal surgery
  • Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs), or other blood-thinners
Detailed Eliquis (apixaban) risks & warnings »
  • History of bleeding problems
  • Severe high blood pressure
  • Older age
  • Heparin-induced thrombocytopenia
Detailed Heparin risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
EliquisHeparin
  • Eliquis (apixaban) can interact with different medicines. Make sure your doctor and pharmacist know all the medicines you're taking.
No interactions related info.
Food
EliquisHeparin
  • Take twice a day, with or without food, at the same time each day.
No food related info.
Kidneys and liver
EliquisHeparin
  • Eliquis (apixaban) is broken down by the kidney and liver. If you already have problems with your kidney or liver, talk to your doctor to make sure Eliquis (apixaban) is right for you.
No kidneys and liver related info.
Upsides and benefits
EliquisHeparin
  • Eliquis (apixaban) is very effective in reducing the risk of stroke in people with atrial fibrilation or other clotting disorders.
  • You don't need to have regular blood tests on Eliquis (apixaban), and you don't have to regulate your diet like other blood thinners.
  • If you've had clots in your legs or lungs before, Eliquis (apixaban) can lower the risk of these forming again.
  • Safe to use in pregnancy and if you're breast feeding.
  • There are other medications that can help stop unexpected bleeding while taking Heparin.
  • Available as a generic medication.
  • Usually used in the hospital, but can be given at home too.
Downsides and risks
EliquisHeparin
  • You can bruise easier and if you cut yourself, it'll take longer to stop the bleeding. Always look for signs of internal bleeding, such as dark urine or bloody stools.
  • Can't be used if you have artificial heart valves.
  • Never stop taking Eliquis (apixaban) without talking to your doctor first.
  • Eliquis (apixaban) isn't available as a generic, so it can be expensive.
  • If you've taken too much Eliquis (apixaban) and you're bleeding, it can be harder to treat compared to other blood thinners.
  • You'll need to get labs/blood draws done on a regular basis to make sure the drug is working and to make sure you don't get unexpected side effects.
  • You can be at higher risk for bleeding or clotting while taking Heparin compared to other anticoagulants.
Tips from our pharmacists for people taking the medication
EliquisHeparin
  • Take twice a day, with or without food, at the same time each day.
  • If you're going to have a dental procedure or surgery, make sure your dentist or surgeon talks to your doctor first.
  • You can bruise easier while taking Eliquis (apixaban) and if you have a cut, it can take longer for bleeding to stop.
  • Eliquis (apixaban) can interact with different medicines. Make sure your doctor and pharmacist know all the medicines you're taking.
  • Call a doctor immediately if you have dizziness, weakness, or a really bad headache.
  • Make sure to change where you inject Heparin every time.
  • Don't take aspirin or other anti-inflammatory medications without talking to your doctor first.
  • You will have to do regular blood draws or labs to make sure that Heparin is working for you.
Learn more
More about EliquisSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Eliquis (apixaban)?
Worth itNot sureNot worth it
More about HeparinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Heparin?
Worth itNot sureNot worth it