Compare Eliquis vs. Pradaxa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Eliquis
(apixaban)

Pradaxa
(dabigatran)

Prevents blood clots. Eliquis (apixaban) is an effective way to prevent blood clots from forming in your veins, but you have to take it twice a day, and your doctor might have to change the dose a lot.Prevents blood clots. Pradaxa (Dabigatran) is a good medication for preventing blood clots. It doesn't require regular blood tests or changing doses often. It can be expensive and there's no way to reverse the medication's effects.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.26Eliquis
Reviews for Eliquis
47%
of people (All ages) say Eliquis is worth it
58%
say it works well
21%
say it's a big hassle
Have you used Eliquis (apixaban)?
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Have you used Pradaxa (dabigatran)?
Worth itNot sureNot worth it
Side effects
EliquisPradaxa
  • Major bleed 2%
  • Bleeding 12%
  • Nausea 3%
  • Low red blood cells 3%
  • All bleeding 15%
  • Nose bleeding 3%
  • Severe bruising 2%
  • Blood in the urine 2%
  • Nosebleeds 3%
  • Blood clots 1%
More Eliquis side effects »
  • Gi side effect 35%
  • Any side effect 21%
  • Any bleed 20%
  • Indigestion 8%
  • Major gastrointestinal bleed 6%
  • Gi bleed 3%
  • Major bleed 3%
  • Gastritis-like symptoms 3%
  • Gastrointestinal bleed 2%
  • Life-threatening bleed 2%
More Pradaxa side effects »
How it works
EliquisPradaxa
Eliquis (apixaban) is a factor Xa inhibitor anticoagulant that stops the formation of blood clots in your body so you're less likely to have a stroke or heart attack.Pradaxa (Dabigatran) is an anticoagulant that stops the formation of blood clots.
Type of medication
EliquisPradaxa
Prescription onlyPrescription only
Available as
EliquisPradaxa
  • Pill
  • Pill
Used for
EliquisPradaxa
Risk factors for serious side effects
EliquisPradaxa
  • Stopping Eliquis (apixaban) prematurely
  • Spinal puncture (spinal tap)
  • Getting anesthesia in the spine (epidural anesthesia)
  • History of spinal surgery
  • Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs), or other blood-thinners
Detailed Eliquis (apixaban) risks & warnings »
  • Stopping Pradaxa (Dabigatran) too soon
  • Spinal tap
  • Anesthesia along the spine (epidural anesthesia)
  • Taking NSAIDs, aspirin, or other blood-thinning medicines
  • Drug interactions
Detailed Pradaxa (dabigatran) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
EliquisPradaxa
  • Eliquis (apixaban) can interact with different medicines. Make sure your doctor and pharmacist know all the medicines you're taking.
No interactions related info.
Food
EliquisPradaxa
  • Take twice a day, with or without food, at the same time each day.
No food related info.
Kidneys and liver
EliquisPradaxa
  • Eliquis (apixaban) is broken down by the kidney and liver. If you already have problems with your kidney or liver, talk to your doctor to make sure Eliquis (apixaban) is right for you.
No kidneys and liver related info.
Upsides and benefits
EliquisPradaxa
  • Eliquis (apixaban) is very effective in reducing the risk of stroke in people with atrial fibrilation or other clotting disorders.
  • You don't need to have regular blood tests on Eliquis (apixaban), and you don't have to regulate your diet like other blood thinners.
  • If you've had clots in your legs or lungs before, Eliquis (apixaban) can lower the risk of these forming again.
  • Clinical studies have shown that the risk of stroke and blood clots is lower than with warfarin, another popular "blood thinner" (anticoagulant).
  • Doesn't require regular blood tests or frequent dose changes.
  • In studies comparing Pradaxa (Dabigatran) to other "blood thinners", it worked just as well in preventing strokes and was better in lowering the risk of bleeding.
Downsides and risks
EliquisPradaxa
  • You can bruise easier and if you cut yourself, it'll take longer to stop the bleeding. Always look for signs of internal bleeding, such as dark urine or bloody stools.
  • Can't be used if you have artificial heart valves.
  • Never stop taking Eliquis (apixaban) without talking to your doctor first.
  • Eliquis (apixaban) isn't available as a generic, so it can be expensive.
  • If you've taken too much Eliquis (apixaban) and you're bleeding, it can be harder to treat compared to other blood thinners.
  • Not available as generic.
  • There are no antidotes to stop bleeding caused by taking too much Pradaxa (Dabigatran).
  • Can't take during pregnancy.
Tips from our pharmacists for people taking the medication
EliquisPradaxa
  • Take twice a day, with or without food, at the same time each day.
  • If you're going to have a dental procedure or surgery, make sure your dentist or surgeon talks to your doctor first.
  • You can bruise easier while taking Eliquis (apixaban) and if you have a cut, it can take longer for bleeding to stop.
  • Eliquis (apixaban) can interact with different medicines. Make sure your doctor and pharmacist know all the medicines you're taking.
  • Call a doctor immediately if you have dizziness, weakness, or a really bad headache.
  • Pradaxa (Dabigatran) is an anticoagulant, so it's important not to miss a dose. Don't stop taking this medication without talking to your doctor first.
  • When taking Pradaxa (Dabigatran), you can bleed more easily, so use a soft toothbrush and an electric razor to avoid cutting yourself.
  • Take this exactly as your doctor or pharmacist tells you to.
  • Take with a full glass of water. Swallow the capsule whole. Don't chew, break, or open the capsule.
Learn more
More about EliquisSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Eliquis (apixaban)?
Worth itNot sureNot worth it
More about PradaxaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Pradaxa (dabigatran)?
Worth itNot sureNot worth it