Compare Emtriva vs. Sustiva

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Works with other medicines to treat HIV infection.

Emtriva (emtricitabine) is a first-line and commonly used drug that is taken in combination with other HIV medications to treat or prevent HIV.

Works with other medicines to treat HIV infection.

Sustiva (efavirenz) is one of the most widely used and effective components of an HIV medication regimen. However, it is not a first-line choice because it can have a lot of side effects.

Upsides
  • Emtriva (emtricitabine) is a first-line drug option used in combination with other HIV medications to treat HIV.
  • Taken with or without food once a day.
  • Emtriva (emtricitabine) is available in many combination tablets if you are looking to lower the number of pills you need to take daily for HIV treatment.
  • Emtriva (emtricitabine) is available as a capsule as well as liquid form.
  • If first-line choices for HIV medications are not an option, Sustiva (efavirenz) would be a good alternative to consider.
  • Only taken once daily.
  • Sustiva (efavirenz) is available in combination tablets.
  • Can be used in patients with mild to moderate kidney damage.
  • Can be used in children who are at least 3 months old.
Downsides
  • Patients with kidney damage will need to be closely monitored by their doctors in order to provide an appropriate dose.
  • Cannot be used by itself to treat or prevent HIV infection.
  • Not suggested for women who plan on becoming pregnant.
  • Many people exerience intolerable side effects (eg. insomnia, dizziness, abnormal dreams, confusion), which make it hard to take the medication regularly.
  • Cannot be taken alone for treatment of HIV.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
Lowest price
$1007.22
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Reviews
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Side effects
18possible side effects
  • Diarrhea
    23%
  • Nausea
    18%
  • Nasal stuffiness/runniness (Rhinitis)
    18%
  • Rash
    17%
  • Physical weakness and/or lack of energy
    16%
  • Increased cough
    14%
  • Headache
    13%
  • Vomiting
    9%
  • Abdominal pain
    8%
  • Insomnia
    7%
  • Depressive disorders
    6%
  • "Pins and needles" feeling (paresthesia)
    5%
  • Dyspepsia
    4%
  • Muscle pain
    4%
  • Dizziness
    4%
  • Nerve weakness/numbness/pain
    4%
  • Joint pain
    3%
  • Abnormal dreams
    2%
See more detailed side effects
19possible side effects
  • Skin rash
    16%
  • Diarrhea
    14%
  • Pain
    13%
  • Nausea
    10%
  • Dizziness
    9%
  • Itching
    9%
  • Fatigue
    8%
  • Headache
    8%
  • Insomnia
    7%
  • Vomiting
    6%
  • Trouble concentrating
    5%
  • Depression
    5%
  • Indigestion
    4%
  • Anxiety
    4%
  • Abnormal dreams
    3%
  • Abdominal pain
    3%
  • Sleepiness
    2%
  • Nervousness
    2%
  • Loss of appetite
    2%
See more detailed side effects
Risks and risk factors
  • Lactic acidosis | Enlarged, fatty liver
    • Liver disease
    • Women
    • Obesity
  • Worsening hepatitis B infection
    • Hepatitis B Virus infection
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Similar medications
    • HIV treatment
  • Kidney Damage
    • History of kidney damage
See more detailed risks and warnings
  • Central nervous system (CNS) effects
    • Starting Sustiva (efavirenz) for the first few weeks.
    • Taking alcohol or other drugs that also affect your nervous system
  • Fat redistribution
    • HIV treatment
  • Liver damage
    • History of liver damage
    • Alcohol intake
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Psychiatric effects
    • History of mental illness
    • History of substance abuse
  • Rash
    • History of severe skin reactions
    • Children
See more detailed risks and warnings