Compare Emtriva vs. Zerit

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Emtriva
(emtricitabine)

Zerit
(stavudine)

Works with other medicines to treat HIV infection. Emtriva (emtricitabine) is a first-line and commonly used drug that is taken in combination with other HIV medications to treat or prevent HIV.Works with other medicines to treat HIV infection. Within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class, stavudine can be a difficult drug to take. stavudine has numerous serious side effects and probably won't be your first choice.
Reviews & ratings
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Have you used Emtriva (emtricitabine)?
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Have you used Zerit (stavudine)?
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Side effects
EmtrivaZerit
  • Diarrhea 23%
  • Nasal stuffiness/runniness (rhinitis) 18%
  • Nausea 18%
  • Rash 17%
  • Physical weakness and/or lack of energy 16%
  • Increased cough 14%
  • Headache 13%
  • Vomiting 9%
  • Abdominal pain 8%
  • Sleep difficulty 7%
More Emtriva side effects »

We haven’t found good data for Zerit side effects.

FDA side effect reports for Zerit »
How it works
EmtrivaZerit
Emtriva (emtricitabine) is a Nucleoside reverse transcriptase inhibitor (NRTI). It treats HIV by stopping the virus from replicating within cells in your immune system.stavudine stops the replication of the human immunodeficiency virus (HIV) within important cells of the body by preventing the virus from taking over normal functions of the cell for its own purposes.
Type of medication
EmtrivaZerit
Prescription only
Available as
EmtrivaZerit
  • Pill
  • Liquid
  • Pill
  • Liquid
Used for
EmtrivaZerit
  • HIV Infection
Risk factors for serious side effects
EmtrivaZerit
  • Liver disease
  • Women
  • Obesity
  • Hepatitis B Virus infection
  • HIV
Detailed Emtriva (emtricitabine) risks & warnings »
  • Use of hydroxyurea, didanosine, and stavudine together
  • HIV
  • Exposure to other infections
  • Start of a new HIV medication
  • Change in HIV therapy
Detailed Zerit (stavudine) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
EmtrivaZerit
No interactions related info.
  • Interacts with many different medications.
Food
EmtrivaZerit
  • Emtriva (emtricitabine) should be taken at the same time everyday, with or without food.
  • Taken with or without food once a day.
  • Take with or without food.
Kidneys and liver
EmtrivaZerit
  • The dose of Emtriva (emtricitabine) should be adjusted if you have poor kidney health. Your doctor will provide lab tests to ensure you are taking the appropriate dose. Be sure to attend your scheduled doctor and lab appointments in order to make sure that Emtriva (emtricitabine) is working well and safely for you.
  • Patients with kidney damage will need to be closely monitored by their doctors in order to provide an appropriate dose.
  • stavudine can cause this rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use stavudine. It may not be a good choice for people with liver problems.
  • May cause serious side effects in your liver, kidneys, and pancreas.
Upsides and benefits
EmtrivaZerit
  • Emtriva (emtricitabine) is a first-line drug option used in combination with other HIV medications to treat HIV.
  • Taken with or without food once a day.
  • Emtriva (emtricitabine) is available in many combination tablets if you are looking to lower the number of pills you need to take daily for HIV treatment.
  • Emtriva (emtricitabine) is available as a capsule as well as liquid form.
  • stavudine is provided as both capsules and an oral solution.
  • Take with or without food.
  • Can be used by patients on dialysis.
  • While stavudine doesn’t cure HIV, it does reduce the number of viral copies being made in your blood, giving your healthy immune cells (CD4 cells) a better chance to do their job.
Downsides and risks
EmtrivaZerit
  • Patients with kidney damage will need to be closely monitored by their doctors in order to provide an appropriate dose.
  • Cannot be used by itself to treat or prevent HIV infection.
  • Must take twice a day, every 12 hours.
  • The amount of stavudine you will take is based on your body weight, kidney, and liver function.
  • Interacts with many different medications.
  • May cause serious side effects in your liver, kidneys, and pancreas.
  • Can cause significant tingling in your hands or feet.
Tips from our pharmacists for people taking the medication
EmtrivaZerit
  • Emtriva (emtricitabine) should be taken at the same time everyday, with or without food.
  • For missed doses, take one if you remember within 12 hours of your regularly scheduled time. Don't take extra medicine or double up if you've missed a previous dose.
  • Keep your regularly scheduled doctor's and lab appointments. These help ensure your medication is working well and safely.
  • Immediately report any signs of liver problems (jaundice, dark urine, yellowing of eyes, etc.) or sensitivity reactions (rash, fever, fatigue, difficulty breathing, etc.) to your prescriber.
  • Set a timer on your phone to make sure you don't forget to take stavudine at the right time.
  • Talk with your doctor about all other medications you are taking since stavudine interacts with many other drugs.
  • Work with your doctor to get regular blood tests. The goal is to make sure the drug is working well and safely.
  • Keep an eye out for any new symptoms or side effects you may start to feel while taking stavudine and report them to your doctor.
Learn more
More about EmtrivaSide effectsAlternativesFDA package insert
Have you used Emtriva (emtricitabine)?
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More about ZeritSide effectsAlternativesFDA package insert
Have you used Zerit (stavudine)?
Worth itNot sureNot worth it