Compare Enalapril vs. Avapro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Vasotec
(enalapril)

Avapro
(irbesartan)

Lowers blood pressure. Enalapril is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Avapro (irbesartan) is a good blood pressure-lowering medicine that protects your kidneys and has few side effects.
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Coupons for Enalapril
Best available price for 30 (20mg) tablets of enalapril
Coupons for Avapro
Best available price for 30 (300mg) tablets of irbesartan
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.26Enalapril
Reviews for Enalapril
44%
of people (All ages) say Enalapril is worth it
40%
say it works well
21%
say it's a big hassle
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Have you used Avapro (irbesartan)?
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Side effects
EnalaprilAvapro
  • Low blood pressure 7%
  • Positional low blood pressure 2%
  • Muscle weakness 2%
  • Orthostatic effects 2%
  • Fainting 2%
More Enalapril side effects »
  • Fatigue 1%
  • Diarrhea 1%
  • Heartburn 1%
More Avapro side effects »
How it works
EnalaprilAvapro
Enalapril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Avapro (irbesartan) is an angiotensin receptor blocker (ARB). It lowers blood pressure by blocking a chemical that tightens the blood vessels. This allows more blood and oxygen to get to your heart and other organs.
Type of medication
EnalaprilAvapro
Prescription onlyPrescription only
Available as
EnalaprilAvapro
  • Pill
  • Liquid
  • Pill
Used for
EnalaprilAvapro
Risk factors for serious side effects
EnalaprilAvapro
  • Women of childbearing age
  • African descent
  • Current kidney problems
  • Medicine that increase potassium
  • Use of salt substitute
Detailed Vasotec (enalapril) risks & warnings »
  • Women of childbearing age
  • History of kidney problems
  • African descent
  • Current kidney problems
  • Using medicines that increase potassium
Detailed Avapro (irbesartan) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Kidneys and liver
EnalaprilAvapro
  • Requires routine blood tests to check kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Avapro (irbesartan) can hurt your kidneys. If you already have kidney damage, Avapro (irbesartan) could make it worse. Your doctor will do regular blood tests to check your kidneys, usually before you start Avapro (irbesartan), and at least once a year while you're still on it.
  • You'll need to have blood tests done regularly since Avapro (irbesartan) can affect your kidneys and potassium levels.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
Upsides and benefits
EnalaprilAvapro
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • The only ACE inhibitor that doctors can give through an IV if that's needed.
  • Avapro (irbesartan) lowers your risk of heart attack and stroke.
  • It works similar to ACE inhibitors (like lisinopril), but it doesn't have the same side effects like coughing and facial swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • It's recommended for people with heart failure since it lowers the risk of death and further damage to your heart.
  • Available in generic, and available with hydrochlorothiazide as a combination tablet.
Downsides and risks
EnalaprilAvapro
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Compared to other ACE inhibitors, less flexible on when you take it. Enalapril needs to be taken multiple times a day on an empty stomach.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • You'll need to get yearly blood tests while taking Avapro (irbesartan) to see how it is affecting your body.
  • It's not safe to use Avapro (irbesartan) if you're pregnant.
  • Avapro (irbesartan) can cause the level of potassium in your blood to go up.
  • You'll need to get medical help if you notice any unusual swelling around your head and neck.
  • Can't be used in children under 18.
Tips from our pharmacists for people taking the medication
EnalaprilAvapro
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
  • Requires routine blood tests to check kidney function.
  • Don't take it if you're pregnant.
  • Avapro (irbesartan) can make you feel a little dizzy for the first few days.
  • You'll need to have blood tests done regularly since Avapro (irbesartan) can affect your kidneys and potassium levels.
  • Don't eat a lot of foods that are high in potassium or use salt substitutes that contain potassium.
  • Tell your doctor about any dizziness or muscle weakness that doesn't go away after the first few days.
  • Don't take Avapro (irbesartan) if you're pregnant.
Learn more
More about EnalaprilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Vasotec (enalapril)?
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More about AvaproSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Avapro (irbesartan)?
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