Compare Enalapril vs. Benicar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Vasotec
(Enalapril)

Benicar
(Olmesartan)

Lowers blood pressure. Enalapril is a good blood pressure-lowering medicine that protects kidney function.Lowers blood pressure. Benicar (Olmesartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.26Enalapril
Reviews for Vasotec (Enalapril)
44%
of people (All ages) say Vasotec (Enalapril) is worth it
40%
say it works well
21%
say it's a big hassle
Have you used Vasotec (Enalapril)?
Worth itNot sureNot worth it
Reviews for Benicar (Olmesartan)
65%
+21% better vs. Vasotec (Enalapril)
63%
+23% better vs. Vasotec (Enalapril)
12%
+9% better vs. Vasotec (Enalapril)
118 reviews
Have you used Benicar (Olmesartan)?
Worth itNot sureNot worth it
Side effects
EnalaprilBenicar
  • Low blood pressure 7%
  • Positional low blood pressure 2%
  • Muscle weakness 2%
  • Orthostatic effects 2%
  • Fainting 2%
More Enalapril side effects »
  • Dizziness 2%
More Benicar side effects »
How it works
EnalaprilBenicar
Enalapril is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.Benicar (Olmesartan) is an angiotensin receptor blocker (ARB). It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.
Type of medication
EnalaprilBenicar
Prescription only
Prescription only
Available as
EnalaprilBenicar
  • Pill
  • Liquid
  • Pill
Used for
EnalaprilBenicar
Risk factors for serious side effects
EnalaprilBenicar
  • Women of childbearing age
    • African descent
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
    Detailed Vasotec (Enalapril) risks & warnings »
      • African descent
      • Current kidney problems
      • Medicine that increase potassium
      • Use of salt substitute
        Detailed Benicar (Olmesartan) risks & warnings »
        Pregnancy

        Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Kidneys and liver
        EnalaprilBenicar
        • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
        • Requires routine blood tests to check kidney function.
        • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
        • Requires routine blood tests to check kidney function.
        Weight
        EnalaprilBenicar
        No weight related info.
        • Benicar (Olmesartan) has been reported to cause severe diarrhea and weight loss unexplained by other causes. Stay hydrated and notify your doctor if you continue to have more than 3-4 loose stools a day.
        Upsides and benefits
        EnalaprilBenicar
        • A first-choice blood pressure treatment for many people.
        • Lowers the risk of heart attack and stroke.
        • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
        • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
        • The only ACE inhibitor that doctors can give through an IV if that's needed.
        • A first-choice blood pressure treatment for many people.
        • Lowers the risk of heart attack and stroke.
        • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
        • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
        • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
        Downsides and risks
        EnalaprilBenicar
        • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
        • Compared to other ACE inhibitors, less flexible on when you take it. Enalapril needs to be taken multiple times a day on an empty stomach.
        • Requires a yearly blood test to see how the medicine is affecting your body.
        • Not safe to use if you're pregnant.
        • Requires a yearly blood test to see how the medicine is affecting your body.
        • Not safe to use if you're pregnant.
        • Not available in less expensive generic form.
        Tips from our pharmacists for people taking the medication
        EnalaprilBenicar
        • Can cause dizziness in the first few days.
        • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
        • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
        • Requires routine blood tests to check kidney function.
        • Don't take it if you're pregnant.
        • Can cause dizziness in the first few days.
        • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
        • Tell your doctor about any dizziness, fatigue, cough, or throat irritation that doesn't go away.
        • Requires routine blood tests to check kidney function.
        • Don't take it if you're pregnant.
        Learn more
        More about EnalaprilSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Vasotec (Enalapril)?
        Worth itNot sureNot worth it
        More about BenicarSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Benicar (Olmesartan)?
        Worth itNot sureNot worth it