Compare Enbrel vs. Remicade

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Enbrel (etanercept)

Prescription only

Remicade (infliximab)

Prescription only
Calms down your immune system to prevent joint damage.

Enbrel (etanercept) effectively calms down your immune system, but it puts you at risk of serious infections.

3.7/ 5 average rating with 90 reviewsforEnbrel
Calms down your immune system.

Remicade (infliximab) is an effective treatment for many autoimmune diseases, but you can have serious side effects.

4.0/ 5 average rating with 55 reviewsforRemicade
Upsides
  • People taking Enbrel (etanercept) for rheumatoid arthritis showed significant improvement and were able to reduce the dose or stop their other RA medicines.
  • Enbrel (etanercept) can work for you even if other medications didn't help your rheumatoid arthritis.
  • Enbrel (etanercept) is the first biologic approved for moderate to severe rheumatoid arthritis. Since it has been around for a long time, its side effects are well known.
  • Many people have only minor or no side effects.
  • It's available as a pre-filled syringe and SureClick auto-injector pen which some people find more convenient and easier to use.
  • People taking Remicade (infliximab) for ulcerative colitis, Crohn's disease, rheumatoid arthritis and other autoimmune conditions had more clinical response, clinical remission and symptom improvement compared to people who did not take Remicade (infliximab).
  • People who were also taking steroids for treatment were able to discontinue steroid use while taking Remicade (infliximab).
  • Remicade (infliximab) has almost two decades of clinical trial data and real-life experience with many people who have used it.
  • After the initial dosing, you only need to take Remicade (infliximab) every 6-8 weeks, depending on your condition.
  • Compared to other medications used to treat autoimmune conditions, Remicade (infliximab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
Downsides
  • Enbrel (etanercept) raises your risk of serious or life-threatening infections, including tuberculosis (TB).
  • Enbrel (etanercept) can increase the risk of lymphoma, leukemia and other cancers.
  • May not be the best choice if you have a history of heart failure or nervous system problems like multiple sclerosis.
  • You'll need to have regular blood tests before and during treatment to make sure you don't have any problems taking Enbrel (etanercept).
  • You could get injection site reactions such as redness, swelling, rash, itching, or bruising.
  • You have to receive this medication at your doctor's office or clinic. You might need to be tested regularly for tuberculosis.
  • Remicade (infliximab) lowers your ability to fight infection and can cause serious illness. The risk is greater if you take other drugs that lower your immune system, or have a history of diabetes or tuberculosis.
  • Remicade (infliximab) can in some cases worsen symptoms of heart failure or neurologic conditions. People 65 years and older may have more side effects from this medication.
  • In rare cases, Remicade (infliximab) has been associated with cancers in children and adolescents.
  • No generic available, so it can be costly.
Used for
Dosage forms
  • Injection
  • Injection
Price
Lowest price
$4537.83
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Lowest price
$20695.40
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Reviews
90 reviews so far
62%
saidit'sworth it
53%
saiditworked well
17%
saidit'sa big hassle

Have you used Enbrel (etanercept)?

Leave a review
55 reviews so far
76%
saidit'sworth it
62%
saiditworked well
15%
saidit'sa big hassle

Have you used Remicade (infliximab)?

Leave a review
Side effects
5possible side effects
  • Any infection
    27%
  • Upper respiratory infections
    17%
  • Injection site reactions
    15%
  • Non-upper respiratory infections
    12%
  • Diarrhea
    3%
See more detailed side effects
The Remicade (infliximab) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Serious allergic reactions
    • Latex allergy
  • Heart problems
    • History of heart failure
  • Serious infections
    • Taking other immunosuppressant drugs
    • Age 65 or older
  • Cancer
    • Taking other immunosuppressant drugs
    • History of cancer
  • Nervous system effects
    • History of nervous system conditions
  • Lower blood cell counts
See more detailed risks and warnings
  • Serious infections
    • Taking other immunosuppressant drugs
    • Age 65 or older
    • Comorbidities
  • Cancer
    • Taking other immunosuppressant drugs
    • History of malignancy
  • Heart failure
    • History of heart failure
    • Receiving higher doses
  • Nervous system effects
    • History of nerve problems
  • Lower blood cell counts
    • Ongoing or history of blood problems
  • Liver injury
See more detailed risks and warnings
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Disclaimer: We don't provide medical advice. If you think you might have a medical emergency, call your doctor or 911 immediately.