Compare Epivir vs. Zerit

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Epivir
(Lamivudine)

Zerit
(Stavudine)

Works with other medicines to treat HIV infection. lamivudine is currently one of the most popular drugs within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class.Works with other medicines to treat HIV infection. Within the Nucleoside Reverse Transcriptase Inhibitor (NRTI) drug class, stavudine can be a difficult drug to take. stavudine has numerous serious side effects and probably won't be your first choice.
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Reviews & ratings
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Side effects
EpivirZerit

We haven’t found good data for Epivir side effects.

FDA side effect reports for Epivir »

We haven’t found good data for Zerit side effects.

FDA side effect reports for Zerit »
How it works
EpivirZerit
lamivudine stops the replication of the human immunodeficiency virus (HIV) within important cells of the body by preventing the virus from taking over normal functions of the cell for its own purposes.stavudine stops the replication of the human immunodeficiency virus (HIV) within important cells of the body by preventing the virus from taking over normal functions of the cell for its own purposes.
Type of medication
EpivirZerit
Coming soon.
Coming soon.
Available as
EpivirZerit
  • Pill
  • Liquid
  • Pill
  • Liquid
Used for (click to learn more)
EpivirZerit
  • HIV infection
  • HIV infection
Risk factors for serious side effects
EpivirZerit
  • Women
  • Obesity
  • Liver disease
        • HIV
        • Exposure to other infections
        • Start of a new HIV medication
        • Change in HIV therapy
        • HIV treatment
        Detailed Epivir (Lamivudine) risks & warnings »
            • Use of hydroxyurea, didanosine, and stavudine together
              • HIV
              • Exposure to other infections
              • Start of a new HIV medication
              • Change in HIV therapy
              • HIV treatment
              Detailed Zerit (Stavudine) risks & warnings »
              Pregnancy category
              EpivirZerit
              CFDA pregnancy category (Weigh risks vs. benefits)

              Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              See the FDA package insert
              CFDA pregnancy category (Weigh risks vs. benefits)

              Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

              See the FDA package insert
              Alcohol
              No specific alcohol-related info.No specific alcohol-related info.
              Food
              No specific food-related info.
              • Take with or without food.
              Kidneys and liver
              • The dose of lamivudine needs to be lowered if you have kidney problems.
              • lamivudine can cause this rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use lamivudine. It may not be a good choice for people with liver problems.
              • The amount of stavudine you will take is based on your body weight, kidney, and liver function.
              • May cause serious side effects in your liver, kidneys, and pancreas.
              • stavudine can cause this rare but life-threatening condition. Symptoms include deep and rapid breathing, nausea, vomiting, and stomach pain. This is a medical emergency and you should get help right away. Baseline blood work for kidney and liver function are helpful to see if you can use stavudine. It may not be a good choice for people with liver problems.
              Sex
              No specific sex-related info.No specific sex-related info.
              Sleep
              No specific sleep-related info.No specific sleep-related info.
              Weight
              No specific weight-related info.
              • The amount of stavudine you will take is based on your body weight, kidney, and liver function.
              Upsides and benefits
              EpivirZerit
              • lamivudine is available as a tablet and oral solution.
              • Can be taken once or twice a day.
              • One of the more popular drugs in its class.
              • lamivudine is contained in the following combination products: Combivir, Epzicom, and Trizivir.
              • stavudine is provided as both capsules and an oral solution.
              • Take with or without food.
              • Can be used by patients on dialysis.
              • While stavudine doesn’t cure HIV, it does reduce the number of viral copies being made in your blood, giving your healthy immune cells (CD4 cells) a better chance to do their job.
              Downsides and risks
              EpivirZerit
              • lamivudine should not be used with any other drugs containing Emtriva (emtricitabine) since both are so similar to each other.
              • Use with caution in kids with a history of pancreatitis (pancreas infection).
              • Most common side effects are headache, nausea, tiredness, congestion, diarrhea, and cough.
              • The dose of lamivudine needs to be lowered if you have kidney problems.
              • Must take twice a day, every 12 hours.
              • The amount of stavudine you will take is based on your body weight, kidney, and liver function.
              • Interacts with many different medications.
              • May cause serious side effects in your liver, kidneys, and pancreas.
              • Can cause significant tingling in your hands or feet.
              Tips from our pharmacists for people taking the medication
              EpivirZerit
              • The doses for lamivudine are different for HIV and Hepatitis B.
              • If being used for kids, the dose of lamivudine will continue to change as they grow, so keep in touch with their doctor.
              • Keep an eye out for any new symptoms or side effects you may start to feel while taking lamivudine and report them to your doctor.
              • Set a timer on your phone to make sure you don't forget to take stavudine at the right time.
              • Talk with your doctor about all other medications you are taking since stavudine interacts with many other drugs.
              • Work with your doctor to get regular blood tests. The goal is to make sure the drug is working well and safely.
              • Keep an eye out for any new symptoms or side effects you may start to feel while taking stavudine and report them to your doctor.
              Learn more
              More about EpivirSide effectsAlternativesFDA package insert
              More about ZeritSide effectsAlternativesFDA package insert