Compare Epzicom vs. Truvada

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Epzicom
(abacavir / lamivudine)

Truvada
(emtricitabine / tenofovir)

Works with other medicines to treat HIV infection. Epzicom (abacavir / lamivudine) contains two medicines in one tablet, used with other medicines, to treat HIV infection. Your doctor does need to test you before you start it to make sure you don't get an allergic reaction.Works with other medicines to treat HIV infection. Truvada (Emtricitabine / Tenofovir) is a popular combination medicine that has two drugs with the same mechanism of action to treat and prevent HIV infection.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Epzicom (abacavir / lamivudine)?
Worth itNot sureNot worth it
Reviews for Truvada
100%
-100% worse vs. Epzicom
94%
-94% worse vs. Epzicom
0%
Same vs. Epzicom
Have you used Truvada (emtricitabine / tenofovir)?
Worth itNot sureNot worth it
Side effects
EpzicomTruvada
  • Severe allergic reaction 9%
  • Depression/depressed mood 7%
  • Headache/migraine 7%
  • Sleep difficulty 7%
  • Fatigue/feeling unwelle/malaise 6%
  • Dizziness/vertigo 6%
  • Nausea 5%
  • Diarrhea 5%
  • Rash 5%
  • Fever 5%
More Epzicom side effects »
  • > 5% bone mineral density loss 7%
  • Headache 1%
  • Syphilis 1%
  • Secondary syphilis 2%
  • Abdominal pain 2%
More Truvada side effects »
How it works
EpzicomTruvada
Epzicom (abacavir / lamivudine) contains two different nucleoside reverse transcriptase inhibitors. It treats HIV infections by preventing the virus from multiplying in your immune cells.Truvada (Emtricitabine / Tenofovir) is a combination medication that stops the replication of the human immunodeficiency virus (HIV) within important cells of the body. Emtricitabine and tenofovir both prevent the virus from taking over normal functions of the cell for its own purposes.
Type of medication
EpzicomTruvada
Prescription only
Available as
EpzicomTruvada
  • Pill
  • Pill
Used for
EpzicomTruvada
Risk factors for serious side effects
EpzicomTruvada
  • Previous allergic reaction to Triumeq or abacavir
  • Presence of HLA-B*5701 gene
  • Liver disease
  • Women
  • Obesity
Detailed Epzicom (abacavir / lamivudine) risks & warnings »
  • Infection with chronic hepatitis B and stopping Truvada (Emtricitabine / Tenofovir)
  • Taking high dose anti-inflammatory drugs (NSAIDs)
  • Undiscovered HIV infection
Detailed Truvada (emtricitabine / tenofovir) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Alcohol
EpzicomTruvada
  • Avoid drinking alcohol when taking Epzicom (abacavir / lamivudine).
No alcohol related info.
Food
EpzicomTruvada
  • Can be taken with or without food.
No food related info.
Kidneys and liver
EpzicomTruvada
  • Severe worsening of Hepatitis B has been seen in patients who have stopped taking Epzicom (abacavir / lamivudine). Your doctor will do regular blood tests to check your liver. Immediately report any signs of liver problems (jaundice, dark urine, yellowing of eyes, etc.) to your doctor.
  • Epzicom (abacavir / lamivudine) isn't recommended if you'll need to adjust the dose of medications due to problems like kidney and/or liver damage.
  • Before starting Truvada (Emtricitabine / Tenofovir), your doctor will test you for hepatitis B to make sure you're not infected. People who've stopped Truvada (Emtricitabine / Tenofovir) and had chronic hepatitis B have suffered from liver damage and failure.
  • People on Truvada (Emtricitabine / Tenofovir) have reported kidney damage, which can be made worse if you take high doses of anti-inflammatory drugs called NSAIDs (Motrin/Advil, Aleve, Mobic, Voltaren, etc.). Call your doctor if you develop bone pain, pain in your arms or legs, or pain or weakness in your muscles.
  • Can cause unusual dreams, or kidney or liver damage.
  • Truvada (Emtricitabine / Tenofovir) is removed from the body by the kidneys, so the dose of Truvada (Emtricitabine / Tenofovir) needs to be lowered if you have any kidney problems.
Weight
EpzicomTruvada
  • Epzicom (abacavir / lamivudine) can be taken by children weighng at least 55lbs (25kg) or more.
No weight related info.
Upsides and benefits
EpzicomTruvada
  • Epzicom (abacavir / lamivudine) contains two first choice medicines used in combination with other medicines to treat HIV infections.
  • Compared to other HIV medicines, Epzicom (abacavir / lamivudine) does not have as many drug interactions with other medicines.
  • Can be taken with or without food.
  • Epzicom (abacavir / lamivudine) can be taken by children weighng at least 55lbs (25kg) or more.
  • First-line treatment for preventing HIV infection in combination with other HIV medications.
  • Only has to be taken once a day.
  • Truvada (Emtricitabine / Tenofovir) prevents and treats HIV infection.
  • Used for preventing HIV infection in case you've been accidentally exposed or if you're in danger of being exposed.
Downsides and risks
EpzicomTruvada
  • Epzicom (abacavir / lamivudine) isn't recommended if you'll need to adjust the dose of medications due to problems like kidney and/or liver damage.
  • Epzicom (abacavir / lamivudine) can increase your risk of heart attack, especially if you have other heart-related issues such as high blood pressure, high cholesterol, diabetes, or if you smoke.
  • Severe allergic reactions have happened in some patients taking Epzicom (abacavir / lamivudine). Your doctor will test you for any possible risk of reaction before starting Epzicom (abacavir / lamivudine).
  • Has to be taken at the same time every day or your body can become resistant to the medication.
  • Can't be taken on its own to treat HIV.
  • Can cause unusual dreams, or kidney or liver damage.
  • Can't be taken with any drugs containing lamivudine since both are so similar to each other.
  • Truvada (Emtricitabine / Tenofovir) is removed from the body by the kidneys, so the dose of Truvada (Emtricitabine / Tenofovir) needs to be lowered if you have any kidney problems.
Tips from our pharmacists for people taking the medication
EpzicomTruvada
  • Avoid drinking alcohol when taking Epzicom (abacavir / lamivudine).
  • Immediately report any signs of liver problems (jaundice, dark urine, yellowing of eyes, etc.) or sensitivity reactions (rash, fever, fatigue, difficulty breathing, etc.) to your doctor.
  • Epzicom (abacavir / lamivudine) will not stop HIV from being transmitted so continue to practice safe behaviors that can stop this from happening, like safer sex and drug use habits.
  • Don't stop taking Epzicom (abacavir / lamivudine) without talking to your doctor first, especially if you have hepatitis B.
  • Since Truvada (Emtricitabine / Tenofovir) is only taken once a day, try taking it at the same time as your other HIV medications.
  • If being used for kids, the dose of Truvada (Emtricitabine / Tenofovir) will continue to change as they grow, so keep in touch with their doctor.
  • Keep an eye out for any new symptoms or side effects you may start to feel while taking Truvada (Emtricitabine / Tenofovir) and report them to your doctor.
  • Practice safe sex while taking Truvada (Emtricitabine / Tenofovir) since the medication will not stop you from passing HIV to other people.
Learn more
More about EpzicomSide effectsAlternativesFDA package insert
Have you used Epzicom (abacavir / lamivudine)?
Worth itNot sureNot worth it
More about TruvadaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Truvada (emtricitabine / tenofovir)?
Worth itNot sureNot worth it