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(Adapalene / Benzoyl Peroxide)

Topical treatment for acne. Akne-Mycin (Erythromycin) is a very common acne treatment you apply to the skin that may work better when combined with other topical medicines.Coming soon.
How it works
Akne-Mycin (Erythromycin) is a topical antibiotic. It fights bacteria that cause acne in oil (sebaceous) glands, and contains alcohol which dries out acne-affected areas.Coming soon.
Type of medication
Acne agent
Prescription only
Coming soon.
Available as
  • Cream, gel, or ointment
  • Topical solution
  • Cream, gel, or ointment
Used for (click to learn more)
  • Acne vulgaris
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
of people
say Erygel is worth it
say it works well
say it’s a big hassle
of people
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say it works well
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Side effects

The Erygel FDA package insert doesn’t have numbers about how common side effects are.

More about Erygel side effects »

We haven’t found good data for Epiduo side effects.

FDA side effect reports for Epiduo »
Risk factors for serious side effects
  • Coming soon.
Pregnancy category

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

See the FDA package insert
BFDA pregnancy category (Probably safe)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)
No specific alcohol-related info.No specific alcohol-related info.
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
No specific sex-related info.No specific sex-related info.
No specific sleep-related info.No specific sleep-related info.
No specific weight-related info.No specific weight-related info.
Upsides and benefits
  • Applying erythromycin to the skin reduces the amount of acne bacteria and "calms" the skin down (lowers the inflammatory response) in acne.
  • Available in a gel formulation which may be better if your skin is very oily.
  • Better choice if you're pregnant. erythromycin is categorized as pregnancy Category B (likely safe) as compared to similar topical medicines that are Category C (weigh risks vs benefits).
Coming soon.
Downsides and risks
  • There's a risk of irritation with anything you apply to your skin and this is no different. erythromycin, like other topical antibiotics, can cause skin irritation and may appear as redness, peeling, abnormal dryness or stinging, tightening, or burning sensations.
  • It's rare, that a serious allergic reaction would occur, but it's a good idea to test a small area of skin before using on any larger or sensitive areas
  • Studies show it works better when combined with other topical medicines to fight acne and reduce the risk of it losing its effectiveness over time.
  • Can cause severe inflammation of the large intestine (pseudomembranous colitis)
  • Stop using if you don't notice any improvement in your acne after 6-8 weeks. The most time you can use it is three months.
Coming soon.
Tips from our pharmacists for people taking the medication
  • Very commonly used topical antibiotic to treat acne.
  • The only topical erythromycin in a gel formula.
  • Apply a thin film to clean and dry affected skin once or twice a day.
  • It may take 6-8 weeks before you see improvement in your acne.
  • Avoid getting into your eyes, nose or mouth.
  • Let your doctor know if you notice abdominal discomfort, pain or diarrhea after starting this medicine.
  • Using a moisturizer that doesn't block your pores (non-comedogenic) may help lessen common side effects of skin dryness and peeling.
  • Taking good care of your skin is an important part of treating acne. Lightly wash with warm water and non-soap-based or gentle cleanser.
Coming soon.
Learn more
More about ErygelSide effectsReviews & ratingsAlternativesFDA package insert
More about EpiduoSide effectsReviews & ratingsFDA package insert
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