Compare Erygel vs. Minocycline

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Akne-Mycin
(erythromycin)

Solodyn
(minocycline)

Topical treatment for acne. Akne-Mycin (Erythromycin) is a very common acne treatment you apply to the skin that may work better when combined with other topical medicines.Treats bacterial infections. Solodyn (Minocycline) is an effective way to treat certain skin infections, acne, and rosacea, but you'll need to use barrier methods of birth control since it can make birth control pills less effective and cause birth defects.
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Coupons for Erygel
Best available price for 1 (30g of 2%) tube of gel of erythromycin
Coupons for Minocycline
Best available price for 60 (100mg) tablets of minocycline
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.55Erygel
Reviews for Akne-Mycin (erythromycin)
46%
of people (All ages) say Akne-Mycin (erythromycin) is worth it
34%
say it works well
19%
say it's a big hassle
Have you used Akne-Mycin (erythromycin)?
Worth itNot sureNot worth it
Reviews for Solodyn (minocycline)
53%
+7% better vs. Akne-Mycin (erythromycin)
59%
+25% better vs. Akne-Mycin (erythromycin)
18%
+1% better vs. Akne-Mycin (erythromycin)
Have you used Solodyn (minocycline)?
Worth itNot sureNot worth it
Side effects
ErygelMinocycline
  • Burning 25%
More Erygel side effects »

We haven’t found good data for Minocycline side effects.

FDA side effect reports for Minocycline »
How it works
ErygelMinocycline
Akne-Mycin (Erythromycin) is a topical antibiotic. It fights bacteria that cause acne in oil (sebaceous) glands, and contains alcohol which dries out acne-affected areas.Solodyn (Minocycline) is a tetracycline antibiotic. It stops bacteria by preventing them from reproducing and repairing themselves.
Type of medication
ErygelMinocycline
Prescription only
Prescription only
Available as
ErygelMinocycline
  • Cream, gel, or ointment
  • Topical solution
  • Pill
  • Extended release
  • Extended release capsule
Used for
ErygelMinocycline
Risk factors for serious side effects
ErygelMinocycline
  • Using other medicines or products that irritate the skin
  • Eczema
  • Extreme temperatures (hot or cold)
Detailed Akne-Mycin (erythromycin) risks & warnings »
  • Age 8 years or younger
  • Using oral birth control pills
  • Long antibiotic treatment period
  • Women of childbearing age
Detailed Solodyn (minocycline) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Price
ErygelMinocycline
No price related info.
  • Available as a generic, so it should be reasonably priced.
Pain
ErygelMinocycline
  • Let your doctor know if you notice abdominal discomfort, pain or diarrhea after starting this medicine.
No pain related info.
Weight
ErygelMinocycline
  • Better choice if you're pregnant. erythromycin is categorized as pregnancy Category B (likely safe) as compared to similar topical medicines that are Category C (weigh risks vs benefits).
No weight related info.
Upsides and benefits
ErygelMinocycline
  • Applying erythromycin to the skin reduces the amount of acne bacteria and "calms" the skin down (lowers the inflammatory response) in acne.
  • Available in a gel formulation which may be better if your skin is very oily.
  • Better choice if you're pregnant. erythromycin is categorized as pregnancy Category B (likely safe) as compared to similar topical medicines that are Category C (weigh risks vs benefits).
  • Clinical studies show it's effective against MRSA, a common skin infection, and it's commonly used to treat acne and rosacea.
  • Available as a generic, so it should be reasonably priced.
  • Solodyn (Minocycline) is less likely to cause sunburn than other tetracycline antibiotics.
  • Bacteria are less likely to become resistant to Solodyn (Minocycline) than other tetracycline antibiotics.
Downsides and risks
ErygelMinocycline
  • There's a risk of irritation with anything you apply to your skin and this is no different. erythromycin, like other topical antibiotics, can cause skin irritation and may appear as redness, peeling, abnormal dryness or stinging, tightening, or burning sensations.
  • It's rare, that a serious allergic reaction would occur, but it's a good idea to test a small area of skin before using on any larger or sensitive areas
  • Studies show it works better when combined with other topical medicines to fight acne and reduce the risk of it losing its effectiveness over time.
  • Can cause severe inflammation of the large intestine (pseudomembranous colitis)
  • Stop using if you don't notice any improvement in your acne after 6-8 weeks. The most time you can use it is three months.
  • It can make birth control pills less effective, so people should use barrier methods of birth control like condoms or diaphragms while on Solodyn (Minocycline).
  • Can stain your teeth, mouth, and gums if you're using the tablets, or your skin if you're using the topical version, but this is temporary.
Tips from our pharmacists for people taking the medication
ErygelMinocycline
  • Very commonly used topical antibiotic to treat acne.
  • The only topical erythromycin in a gel formula.
  • Apply a thin film to clean and dry affected skin once or twice a day.
  • It may take 6-8 weeks before you see improvement in your acne.
  • Avoid getting into your eyes, nose or mouth.
  • Let your doctor know if you notice abdominal discomfort, pain or diarrhea after starting this medicine.
  • Using a moisturizer that doesn't block your pores (non-comedogenic) may help lessen common side effects of skin dryness and peeling.
  • Taking good care of your skin is an important part of treating acne. Lightly wash with warm water and non-soap-based or gentle cleanser.
  • Both men and women should use barrier methods of birth control while on Solodyn (Minocycline) since it can cause birth defects and make birth control pills less effective.
  • Can make you dizzy, so be careful if you're getting up from lying down or sitting. Don't drive until you know how it affects you.
  • Can stain your teeth, tongue and gums, but this is temporary.
  • Take this exactly how your doctor or pharmacist tells you until it's all gone.
  • Don't eat any dairy products or take any vitamins within 2 hours of taking Solodyn (Minocycline) because they can make the medication less effective.
Learn more
More about ErygelSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Akne-Mycin (erythromycin)?
Worth itNot sureNot worth it
More about MinocyclineSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Solodyn (minocycline)?
Worth itNot sureNot worth it