Compare Estazolam vs. Hetlioz

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prosom
(estazolam)

Hetlioz
(tasimelteon)

Helps you stay asleep longer. Prosom (estazolam) can help you sleep, but you might feel hungover the next day.Keeps the sleep cycle normal for completely blind people who aren't able to see light. Hetlioz (tasimelteon) is the only approved medicine to help completely blind people who are unable to see light maintain regular sleep cycles. It is only available as a brand name, so it can be expensive.
Reviews & ratings
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Have you used Prosom (estazolam)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Hetlioz (tasimelteon)?
Worth itNot sureNot worth it
Side effects
EstazolamHetlioz
  • Sleepiness 15%
  • Weakness 3%
  • Difficulty controlling muscles 4%
  • Dizziness 4%
  • Abnormal coordination 3%
  • Leg and foot pain 1%
More Estazolam side effects »
  • Headache 10%
  • Abnormal liver tests 5%
  • Nightmares or abnormal dreams 10%
  • Common cold or flu 7%
  • Urinary tract infection 5%
More Hetlioz side effects »
How it works
EstazolamHetlioz
Prosom (estazolam) is a benzodiazepine. It helps you stay asleep by improving the quality of your sleep so you don't wake up as much at night.Hetlioz (tasimelteon) is a melatonin receptor agonist. It helps you to sleep at night and stay awake during the day.
Type of medication
EstazolamHetlioz
Prescription onlyPrescription only
Available as
EstazolamHetlioz
  • Pill
  • Pill
Used for
EstazolamHetlioz
  • Non 24 Hour Sleep Wake Cycle
Risk factors for serious side effects
EstazolamHetlioz
  • Using Prosom (estazolam) for more than 10 days
  • Drinking alcohol
  • Taking sedative medicines
  • People age 65 or older
Detailed Prosom (estazolam) risks & warnings »
    Detailed Hetlioz (tasimelteon) risks & warnings »
    Pregnancy

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Alcohol
    EstazolamHetlioz
    • Don't drink alcohol or take other narcotics with Prosom (estazolam) because it can slow your breathing.
    No alcohol related info.
    Sleep
    EstazolamHetlioz
    No sleep related info.
    • If you go to sleep at a different time, don't take Hetlioz (tasimelteon).
    Upsides and benefits
    EstazolamHetlioz
    • Prosom (estazolam) is available in generic.
    • Hetlioz (tasimelteon) is not addictive.
    • Hetlioz (tasimelteon) is the only drug that's approved to help people unable to see light to have regular sleep cycles.
    • If you have to stop taking Hetlioz (tasimelteon) suddenly, you're not likely to have withdrawal.
    Downsides and risks
    EstazolamHetlioz
    • Prosom (estazolam) isn't recommended if you're age 65 or older because the side effects can be more intense.
    • You can become dependent on Prosom (estazolam) if you take it for more than a few weeks.
    • If you stop Prosom (estazolam) suddenly after taking it for a while, your insomnia might come back even worse than when you started.
    • Hetlioz (tasimelteon) can take weeks to months for you to notice any effect.
    • Hetlioz (tasimelteon) is only available as a brand name so it can be expensive.
    Tips from our pharmacists for people taking the medication
    EstazolamHetlioz
    • Don't take Prosom (estazolam) unless you know you'll be going to sleep right away.
    • Make sure you can sleep for at least 8 hours before you take it.
    • Prosom (estazolam) works best if you develop good sleeping habits.
    • Take Prosom (estazolam) for the shortest amount of time needed to treat your insomnia since it can be addicting.
    • Don't drink alcohol or take other narcotics with Prosom (estazolam) because it can slow your breathing.
    • Take Hetlioz (tasimelteon) at the same time every night.
    • Take Hetlioz (tasimelteon) on an empty stomach. Swallow capsule whole. Don't crush or chew the capsule.
    • If you go to sleep at a different time, don't take Hetlioz (tasimelteon).
    • Hetlioz (tasimelteon) might take weeks or months before you notice any effects.
    • If you smoke tobacco, Hetlioz (tasimelteon) might not work as well.
    Learn more
    More about EstazolamSide effectsAlternativesFDA package insert
    Have you used Prosom (estazolam)?
    Worth itNot sureNot worth it
    More about HetliozSide effectsFDA package insert
    Have you used Hetlioz (tasimelteon)?
    Worth itNot sureNot worth it